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(Q29521908)
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SMCR8-C9orf72 complex subunit
mammalian protein found in Rattus norvegicus
guanine nucleotide exchange protein SMCR8
Smcr8
Smith-Magenis syndrome chromosomal region candidate gene 8 protein
Smith-Magenis syndrome chromosome region, candidate 8 homolog
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D3ZJR6
part of
Folliculin/SMCR8, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Folliculin/SMCR8, tripartite DENN domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D3ZJR6
encoded by
Smcr8
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D3ZJR6
molecular function
protein kinase inhibitor activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
protein kinase binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
cell component
chromatin
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
nucleoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
cytoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
guanyl-nucleotide exchange factor complex
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
Atg1/ULK1 kinase complex
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
biological process
negative regulation of protein kinase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
regulation of autophagy
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
negative regulation of gene expression
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
negative regulation of macroautophagy
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
positive regulation of TOR signaling
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
positive regulation of autophagosome maturation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
negative regulation of autophagosome assembly
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
regulation of TORC1 signaling
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D3ZJR6
determination method
IEA
has part(s)
Folliculin/SMCR8, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZJR6
Folliculin/SMCR8, tripartite DENN domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/D3ZJR6
Identifiers
RefSeq protein ID
NP_001178848
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
497918
UniProt protein ID
D3ZJR6
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
D3ZJR6
Ensembl protein ID
ENSRNOP00000006984
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000006984
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Multilingual sites
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