(Q29526499)

Kringle-like fold

1 reference

Fibronectin type II domain superfamily

1 reference

Fibronectin type II domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cation-independent mannose-6-phosphate receptor repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

17 November 2021

1 reference

17 November 2021

G-protein alpha-subunit binding

insulin-like growth factor-activated receptor activity

1 reference

9 May 2019

Insulin-like growth factor-II/mannose-6-phosphate receptor: widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

High-affinity prorenin binding to cardiac man-6-P/IGF-II receptors precedes proteolytic activation to renin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

insulin-like growth factor II binding

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

kringle domain binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

signaling receptor activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

identical protein binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

phosphoprotein binding

G-protein alpha-subunit binding

1 reference

9 May 2019

Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

Mannose 6-phosphate/insulin-like growth factor II receptor mediates the growth-inhibitory effects of retinoids

retinoic acid binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

insulin-like growth factor II binding

1 reference

9 May 2019

Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

Mannose 6-phosphate/insulin-like growth factor II receptor mediates the growth-inhibitory effects of retinoids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

9 May 2019

In vitro reconstitution of fusion between immature autophagosomes and endosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

9 May 2019

3-Methyladenine specifically inhibits retrograde transport of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor from the early endosome to the TGN

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

A highly phosphorylated subpopulation of insulin-like growth factor II/mannose 6-phosphate receptors is concentrated in a clathrin-enriched plasma membrane fraction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

clathrin-coated vesicle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

perinuclear region of cytoplasm

nuclear envelope lumen

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

9 May 2019

3-Methyladenine specifically inhibits retrograde transport of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor from the early endosome to the TGN

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

trans-Golgi network transport vesicle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

perinuclear region of cytoplasm

1 reference

9 May 2019

3-Methyladenine specifically inhibits retrograde transport of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor from the early endosome to the TGN

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

Expression and binding properties of the two mannose-6-phosphate receptors differ during perinatal development in rat liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

post-Golgi vesicle-mediated transport

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

G protein-coupled receptor signaling pathway

1 reference

9 May 2019

Activation of insulin-like growth factor II receptor induces mitochondrial-dependent apoptosis through G(alpha)q and downstream calcineurin signaling in myocardial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

Changes in distribution of phosphomannosyl receptors during maturation of rat spermatozoa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

post-embryonic development

IEP

1 reference

9 May 2019

Organ-specific changes in the expression of mannose-6-phosphate receptors during postnatal development in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

1 reference

9 May 2019

Insulin-like growth factor-II/mannose-6-phosphate receptor: widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

animal organ regeneration

TAS

1 reference

9 May 2019

The hepatocyte is a direct target for transforming-growth factor beta activation via the insulin-like growth factor II/mannose 6-phosphate receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

regulation of apoptotic process

IEP

1 reference

9 May 2019

Roles of insulin-like growth factor II in cardiomyoblast apoptosis and in hypertensive rat heart with abdominal aorta ligation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

positive regulation of apoptotic process

IMP

insulin-like growth factor receptor signaling pathway

IMP

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

response to retinoic acid

1 reference

9 May 2019

Retinoic acid alters the intracellular trafficking of the mannose-6-phosphate/insulin-like growth factor II receptor and lysosomal enzymes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

positive regulation of apoptotic process

1 reference

9 May 2019

Activation of insulin-like growth factor II receptor induces mitochondrial-dependent apoptosis through G(alpha)q and downstream calcineurin signaling in myocardial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

positive regulation by host of viral process

IMP

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G3V824

fibronectin type II domain

has part(s)

1 reference

Cation-independent mannose-6-phosphate receptor

1 reference