(Q29547258)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

23 April 2017

1 reference

Wells JA

1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

23 April 2017

McClendon CL

series ordinal

2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

23 April 2017

language of work or name

1 reference

23 April 2017

publication date

13 December 2007

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

23 April 2017

volume

450

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

23 April 2017

issue

7172

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

23 April 2017

page(s)

1001-9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

23 April 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

A protein interaction network of the malaria parasite Plasmodium falciparum

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7 January 2021

Revealing static and dynamic modular architecture of the eukaryotic protein interaction network

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7 January 2021

The protein network as a tool for finding novel drug targets.

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7 January 2021

Identifying functional modules in the physical interactome of Saccharomyces cerevisiae

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7 January 2021

Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map

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7 January 2021

Principles of protein-protein interactions

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7 January 2021

The atomic structure of protein-protein recognition sites

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7 January 2021

Structure-based maximal affinity model predicts small-molecule druggability.

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7 January 2021

Exploring protein-ligand recognition with Binding MOAD

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7 January 2021

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7 January 2021

Benzodiazepine peptidomimetic inhibitors of farnesyltransferase

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7 January 2021

Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs

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7 January 2021

Antagonists of protein-protein interactions.

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7 January 2021

A hot spot of binding energy in a hormone-receptor interface

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7 January 2021

Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity

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7 January 2021

Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site

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7 January 2021

Hot-spot mimicry of a cytokine receptor by a small molecule

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7 January 2021

Hot spots--a review of the protein-protein interface determinant amino-acid residues

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7 January 2021

Convergent solutions to binding at a protein-protein interface

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7 January 2021

Phage display for selection of novel binding peptides

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7 January 2021

Small peptides as potent mimetics of the protein hormone erythropoietin

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7 January 2021

Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

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7 January 2021

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

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7 January 2021

Strategies for targeting protein-protein interactions with synthetic agents.

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7 January 2021

Protein-protein interactions as targets for small molecule drug discovery

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7 January 2021

Protein-protein interactions and cancer: small molecules going in for the kill

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7 January 2021

Binding of small molecules to an adaptive protein-protein interface

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7 January 2021

Discovery of a potent small molecule IL-2 inhibitor through fragment assembly

1 reference

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7 January 2021

Integrating fragment assembly and biophysical methods in the chemical advancement of small-molecule antagonists of IL-2: an approach for inhibiting protein-protein interactions

1 reference

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7 January 2021

The structure of interleukin-2 complexed with its alpha receptor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Potent small-molecule binding to a dynamic hot spot on IL-2

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

NMR characterization of interleukin-2 in complexes with the IL-2Ralpha receptor component, and with low molecular weight compounds that inhibit the IL-2/IL-Ralpha interaction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

The maximal affinity of ligands

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Optimization of binding electrostatics: charge complementarity in the barnase-barstar protein complex.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody

1 reference

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7 January 2021

The Bcl-2 protein family: arbiters of cell survival

1 reference

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7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

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7 January 2021

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

1 reference

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7 January 2021

Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-xL.

1 reference

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7 January 2021

Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL.

1 reference

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7 January 2021

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

1 reference

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7 January 2021

(alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions

1 reference

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7 January 2021

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL

1 reference

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7 January 2021

SAR by NMR: putting the pieces together

1 reference

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7 January 2021

Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesis

1 reference

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7 January 2021

The P53 pathway: what questions remain to be explored?

1 reference

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7 January 2021

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

1 reference

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7 January 2021

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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7 January 2021

Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.

1 reference

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7 January 2021

1,4-Benzodiazepine-2,5-diones as small molecule antagonists of the HDM2-p53 interaction: discovery and SAR.

1 reference

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7 January 2021

Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo

1 reference

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7 January 2021

NMR structure of a complex between MDM2 and a small molecule inhibitor

1 reference

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7 January 2021

Discovery of the first series of inhibitors of human papillomavirus type 11: inhibition of the assembly of the E1-E2-Origin DNA complex

1 reference

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7 January 2021

Inhibition of human papillomavirus DNA replication by small molecule antagonists of the E1-E2 protein interaction

1 reference

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7 January 2021

Crystal structure of the E2 transactivation domain of human papillomavirus type 11 bound to a protein interaction inhibitor

1 reference

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7 January 2021

Optimization and determination of the absolute configuration of a series of potent inhibitors of human papillomavirus type-11 E1-E2 protein-protein interaction: a combined medicinal chemistry, NMR and computational chemistry approach

1 reference

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7 January 2021

The X-ray structure of the papillomavirus helicase in complex with its molecular matchmaker E2.

1 reference

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7 January 2021

The bacterial cell-division protein ZipA and its interaction with an FtsZ fragment revealed by X-ray crystallography

1 reference

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7 January 2021

Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Druggability indices for protein targets derived from NMR-based screening data

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA-FtsZ interaction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Structure-based design and characterization of exocyclic peptidomimetics that inhibit TNF alpha binding to its receptor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-α

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Small-molecule inhibition of TNF-alpha

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Discovery of a novel small molecule binding site of human survivin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Effects of conformational dynamics on predicted protein druggability.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Transient Pockets on Protein Surfaces Involved in Protein−Protein Interaction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Relating protein pharmacology by ligand chemistry

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

A high-throughput screen for aggregation-based inhibition in a large compound library.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Fragment-based lead discovery: leads by design

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Solution structure and dynamics of the complex between cytochrome c and cytochrome c peroxidase determined by paramagnetic NMR

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Visualization of transient encounter complexes in protein-protein association.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Drug-like properties and the causes of poor solubility and poor permeability

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Fragment-based lead discovery: a chemical update

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Refined structure of alpha beta-tubulin at 3.5 A resolution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Crystal structures of cyclophilin and its partners

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

The structure of a yeast hexokinase monomer and its complexes with substrates at 2.7-A resolution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Space-Filling Models of Kinase Clefts and Conformation Changes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Inhibition of protein-protein interactions: The discovery of druglike β-catenin inhibitors by combining virtual and biophysical screening

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Potent inhibition of the CD4-dependent T cell response by J2, a novel nonpeptide organic ligand of CD4 D1.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Discovery of selective small-molecule CD80 inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

Unraveling hot spots in binding interfaces: progress and challenges

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06526

7 January 2021

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

Identifiers

2 references

23 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1038231590

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18075579

PubMed publication ID

2 references

23 April 2017

Consolidated OpenCitations Corpus – April 2017