(Q29547556)

title

Osteoclast differentiation and activation (English)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12748652

osteoclast differentiation

23 April 2017

main subject

0 references

cell differentiation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748652

2 January 2024

author name string

William J. Boyle

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748652

2 January 2024

W. Scott Simonet

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748652

2 January 2024

David L. Lacey

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748652

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12748652

2 January 2024

language of work or name

1 reference

23 April 2017

publication date

15 May 2003

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12748652

full work available at URL

23 April 2017

http://www.nature.com/articles/nature01658.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/NATURE01658

http://www.nature.com/articles/nature01658

2 January 2024

1 reference

https://api.crossref.org/works/10.1038/NATURE01658

http://www.nature.com/doifinder/10.1038/nature01658

2 January 2024

1 reference

https://api.crossref.org/works/10.1038/NATURE01658

2 January 2024

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12748652

23 April 2017

volume

423

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12748652

23 April 2017

page(s)

337-42

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12748652

23 April 2017

issue

6937

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12748652

Bone resorption by osteoclasts

23 April 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

The osteopetrotic mutation toothless (tl) is a loss-of-function frameshift mutation in the rat Csf1 gene: Evidence of a crucial role for CSF-1 in osteoclastogenesis and endochondral ossification

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

RANK is essential for osteoclast and lymph node development

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

RANK-L and RANK: T cells, bone loss, and mammalian evolution

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

Distinct molecular mechanism for initiating TRAF6 signalling

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

NF-kappaB in cancer: from innocent bystander to major culprit

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinase

25 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

Regulation of the differentiation and function of osteoclasts

28 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Therapeutic approaches to bone diseases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

TNFalpha potently activates osteoclasts, through a direct action independent of and strongly synergistic with RANKL

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

https://api.crossref.org/works/10.1038%2FNATURE01658

1 reference

7 January 2021

Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Osteoclast biology: lessons from mammalian mutations

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Mouse models of abnormal skeletal development and homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Genetic control of skeletal development

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1beta, TNF-alpha, PTH, PTHrP, and 1, 25(OH)2D3.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

RANK ligand and osteoprotegerin: paracrine regulators of bone metabolism and vascular function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Requirement for NF-kappaB in osteoclast and B-cell development

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Possible involvement of IkappaB kinase 2 and MKK7 in osteoclastogenesis induced by receptor activator of nuclear factor kappaB ligand

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL)

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Interleukin-4 Reversibly Inhibits Osteoclastogenesis via Inhibition of NF-κB and Mitogen-activated Protein Kinase Signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

U0126 and PD98059, specific inhibitors of MEK, accelerate differentiation of RAW264.7 cells into osteoclast-like cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

The immunosuppressant rapamycin, alone or with transforming growth factor-beta, enhances osteoclast differentiation of RAW264.7 monocyte-macrophage cells in the presence of RANK-ligand

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Transcriptional program of mouse osteoclast differentiation governed by the macrophage colony-stimulating factor and the ligand for the receptor activator of NFkappa B.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

c-myc is required for osteoclast differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

A block at the toll gate

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Regulation of osteoclastogenesis and RANK expression by TGF-beta1.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Catabolic effects of continuous human PTH (1--38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Regulation of receptor activator of NF-kappa B ligand-induced osteoclastogenesis by endogenous interferon-beta (INF-beta ) and suppressors of cytokine signaling (SOCS). The possible counteracting role of SOCSs- in IFN-beta-inhibited osteoclast forma

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Stimulation of osteoprotegerin production is responsible for osteosclerosis in mice overexpressing TPO.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic to familial expansile osteolysis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Osteoprotegerin deficiency and juvenile Paget's disease.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Polymorphisms in the osteoprotegerin gene are associated with osteoporotic fractures

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

The effect of a single dose of osteoprotegerin in postmenopausal women

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Role of RANK ligand in mediating increased bone resorption in early postmenopausal women

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Inhibitory action of bisphosphonates on bone resorption does not involve the regulation of RANKL and OPG expression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01658

7 January 2021

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12748652

Identifiers

2 references

23 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

346259

1019910253

0 references

346259

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12748652

2 references

23 April 2017

Consolidated OpenCitations Corpus – April 2017