(Q296209)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9HC16

Cytidine and deoxycytidylate deaminase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

APOBEC/CMP deaminase, zinc-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein homodimerization activity

1 reference

8 April 2019

An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

cytidine deaminase activity

NAS

1 reference

27 March 2018

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HC16&geneProductId=UniProtKB:Q9HC16

6 references

8 April 2019

HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV-1 Vif.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HC16&geneProductId=UniProtKB:Q9HC16

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

deoxycytidine deaminase activity

1 reference

8 April 2019

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

1 reference

27 March 2018

An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HC16&geneProductId=UniProtKB:Q9HC16

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HC16&geneProductId=UniProtKB:Q9HC16

dCTP deaminase activity

1 reference

10 September 2018

cytidine deaminase activity

TAS

cytidine deaminase activity

IBA

TAS

3 references

8 April 2019

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HC16&geneProductId=UniProtKB:Q9HC16

apolipoprotein B mRNA editing enzyme complex

1 reference

8 April 2019

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HC16&geneProductId=UniProtKB:Q9HC16

27 March 2018

APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HC16&geneProductId=UniProtKB:Q9HC16

27 March 2018

Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HC16&geneProductId=UniProtKB:Q9HC16

27 March 2018

Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HC16&geneProductId=UniProtKB:Q9HC16

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

ribonucleoprotein complex

1 reference

8 April 2019

Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

1 reference

8 April 2019

Restriction of foamy viruses by APOBEC cytidine deaminases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

3 references

8 April 2019

Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

negative regulation of transposition

1 reference

8 April 2019

APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

base conversion or substitution editing

1 reference

10 September 2018

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HC16&geneProductId=UniProtKB:Q9HC16

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

TAS

immune system process

1 reference

8 April 2019

APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons

DNA cytosine deamination

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

positive regulation of defense response to virus by host

1 reference

8 April 2019

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

negative regulation of viral process

1 reference

8 April 2019

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

defense response to virus

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

innate immune response

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

8 April 2019

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

cytidine to uridine editing

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HC16

http://purl.uniprot.org/uniprot/Q9HC16

IBA

exact match

1 reference

Cytidine and deoxycytidylate deaminase domain

Identifiers.org

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9HC16

APOBEC/CMP deaminase, zinc-binding

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9HC16

Identifiers

MeSH descriptor ID

D000071480

subject named as

APOBEC-3G Deaminase

0 references

MeSH tree code

D08.811.277.151.486.250.500.750

0 references

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference