Wikidata

(Q29795009)

English

Forkhead box protein O CELE_R13H8.1

protein found in Caenorhabditis elegans

  • Forkhead box protein O
  • daf-16
  • hypothetical protein
  • Forkhead box protein O;hypothetical protein
  • Daf-16
In more languages

Statements

molecular function
protein binding
determination method
IPI
7 references
retrieved
1 January 2018
stated in
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IPI
retrieved
1 January 2018
stated in
NSBP-1 mediates the effects of cholesterol on insulin/IGF-1 signaling in Caenorhabditis elegans.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IPI
retrieved
1 January 2018
stated in
Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IPI
retrieved
1 January 2018
stated in
C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IPI
retrieved
1 January 2018
stated in
C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IPI
retrieved
1 January 2018
stated in
C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IPI
retrieved
1 January 2018
stated in
Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
14 references
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IEA
retrieved
21 June 2018
stated in
Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
RPN-6 determines C. elegans longevity under proteotoxic stress conditions.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
The zinc matrix metalloproteinase ZMP-2 increases survival of Caenorhabditis elegans through interference with lipoprotein absorption
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
cytoplasm
determination method
IDA
IEA
11 references
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IEA
retrieved
21 June 2018
stated in
Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
The zinc matrix metalloproteinase ZMP-2 increases survival of Caenorhabditis elegans through interference with lipoprotein absorption
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
21 June 2018
stated in
Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O16850&geneProductId=UniProtKB:O16850
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
13 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IEA
retrieved
1 January 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity.
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
RPN-6 determines C. elegans longevity under proteotoxic stress conditions.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
The zinc matrix metalloproteinase ZMP-2 increases survival of Caenorhabditis elegans through interference with lipoprotein absorption
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IBA
cytoplasm
determination method
IBA
IDA
IEA
10 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IEA
retrieved
1 January 2018
stated in
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
The zinc matrix metalloproteinase ZMP-2 increases survival of Caenorhabditis elegans through interference with lipoprotein absorption
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IBA
biological process
determination of adult lifespan
determination method
IDA
IGI
IMP
18 references
retrieved
1 January 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IMP
retrieved
1 January 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IMP
retrieved
1 January 2018
stated in
Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IMP
retrieved
1 January 2018
stated in
Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IMP
retrieved
1 January 2018
stated in
Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IMP
retrieved
1 January 2018
stated in
Mg2+ Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IMP
retrieved
1 January 2018
stated in
A fasting-responsive signaling pathway that extends life span in C. elegans
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IMP
retrieved
1 January 2018
stated in
eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IMP
retrieved
1 January 2018
stated in
Functional interaction between beta-catenin and FOXO in oxidative stress signaling
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IMP
retrieved
1 January 2018
stated in
TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IMP
retrieved
1 January 2018
stated in
Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IGI
retrieved
1 January 2018
stated in
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IGI
retrieved
1 January 2018
stated in
Manipulation of behavioral decline in Caenorhabditis elegans with the Rag GTPase raga-1
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IGI
retrieved
1 January 2018
stated in
A fasting-responsive signaling pathway that extends life span in C. elegans
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IGI
retrieved
1 January 2018
stated in
eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IGI
retrieved
1 January 2018
stated in
Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IGI
retrieved
1 January 2018
stated in
RPN-6 determines C. elegans longevity under proteotoxic stress conditions.
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA
retrieved
1 January 2018
stated in
Combined informatic and expression screen identifies the novel DAF-16 target HLH-13
GOA
curator
UniProt
UniProt protein ID
O16850
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O16850
determination method
IDA

Identifiers

 
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