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Exonuclease mut-7 CELE_ZK1098.8
Protein found in Caenorhabditis elegans
Exonuclease mut-7
mut-7
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P34607
part of
Ribonuclease H superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P34607
Ribonuclease H-like superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P34607
Exonuclease Mut-7, DEDDy 3'-5' exonuclease domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
3'-5' exonuclease domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Mut7-C RNAse domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Caenorhabditis elegans
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P34607
encoded by
mut-7
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P34607
molecular function
nucleic acid binding
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
UniProt-GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IEA
nuclease activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
UniProt-GOA
curator
UniProt
UniProt protein ID
P34607
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IEA
exonuclease activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
UniProt-GOA
curator
UniProt
UniProt protein ID
P34607
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IEA
protein binding
determination method
IPI
2 references
retrieved
1 January 2018
stated in
Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network.
UniProt-GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IPI
retrieved
1 January 2018
stated in
RDE-2 interacts with MUT-7 to mediate RNA interference in Caenorhabditis elegans
UniProt-GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IPI
3'-5' exonuclease activity
determination method
IBA
IEA
2 references
retrieved
1 January 2018
stated in
UniProt-GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IEA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
UniProt-GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IBA
hydrolase activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
UniProt-GOA
curator
UniProt
UniProt protein ID
P34607
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IEA
3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing
determination method
ISS
1 reference
retrieved
1 January 2018
stated in
Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
ISS
metal ion binding
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
UniProt-GOA
curator
UniProt
UniProt protein ID
P34607
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IEA
cell component
nucleus
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
RDE-2 interacts with MUT-7 to mediate RNA interference in Caenorhabditis elegans
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IDA
cytoplasm
determination method
IDA
2 references
retrieved
1 January 2018
stated in
MUT-14 and SMUT-1 DEAD box RNA helicases have overlapping roles in germline RNAi and endogenous siRNA formation.
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IDA
retrieved
1 January 2018
stated in
MUT-16 promotes formation of perinuclear mutator foci required for RNA silencing in the C. elegans germline
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IDA
cytosol
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
RDE-2 interacts with MUT-7 to mediate RNA interference in Caenorhabditis elegans
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IDA
perinuclear region of cytoplasm
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
MUT-16 promotes formation of perinuclear mutator foci required for RNA silencing in the C. elegans germline
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IDA
biological process
negative regulation of transposition, DNA-mediated
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
The rde-1 gene, RNA interference, and transposon silencing in C. elegans
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IMP
nucleobase-containing compound metabolic process
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
UniProt-GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IEA
associative learning
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
C. elegans positive olfactory associative memory is a molecularly conserved behavioral paradigm.
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IMP
olfactory learning
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Endogenous nuclear RNAi mediates behavioral adaptation to odor.
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IMP
RNA interference
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
The rde-1 gene, RNA interference, and transposon silencing in C. elegans
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IMP
posttranscriptional gene silencing
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
The rde-1 gene, RNA interference, and transposon silencing in C. elegans
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IMP
gene silencing by RNA
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
UniProt-GOA
curator
UniProt
UniProt protein ID
P34607
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IEA
mature miRNA 3'-end processing
determination method
ISS
1 reference
retrieved
1 January 2018
stated in
Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.
UniProt-GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
ISS
nucleic acid phosphodiester bond hydrolysis
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
UniProt-GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34607
determination method
IEA
has part
Mut7-C RNAse domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P34607
3'-5' exonuclease domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P34607
Exonuclease Mut-7, DEDDy 3'-5' exonuclease domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P34607
Identifiers
Ensembl protein ID
ZK1098.8
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ZK1098.8
RefSeq protein ID
NP_499105
1 reference
stated in
NCBI Gene
retrieved
14 December 2018
Entrez Gene ID
176347
UniProt protein ID
P34607
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P34607
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