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(Q29808904)
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Atonal Dmel_CG7508
Protein found in Drosophila melanogaster
ato-PA
atona
CG7508-PA
CG7508 gene product from transcript CG7508-RA
atonal
ato
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P48987
part of
Helix-loop-helix DNA-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P48987
Myc-type, basic helix-loop-helix (bHLH) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P48987
encoded by
ato
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P48987
molecular function
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
The proneural proteins Atonal and Scute regulate neural target genes through different E-box binding sites
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IPI
DNA binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P48987
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IEA
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IPI
protein heterodimerization activity
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
The proneural proteins Atonal and Scute regulate neural target genes through different E-box binding sites
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IPI
protein dimerization activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IEA
cell component
nucleus
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P48987
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IEA
retrieved
8 April 2019
stated in
The proneural proteins Atonal and Scute regulate neural target genes through different E-box binding sites
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IDA
biological process
Bolwig's organ morphogenesis
determination method
IEP
1 reference
retrieved
8 April 2019
stated in
Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IEP
insect visual primordium development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The control of cell fate in the embryonic visual system by atonal, tailless and EGFR signaling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P48987
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IEA
nervous system development
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P48987
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IEA
brain development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
sensory organ development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Role of proneural genes in the formation of the larval olfactory organ of Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
oenocyte development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
abdominal A specifies one cell type in Drosophila by regulating one principal target gene.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
eye-antennal disc morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Epithelial cell adhesion in the developing Drosophila retina is regulated by Atonal and the EGF receptor pathway
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
R8 cell fate commitment
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Atonal is the proneural gene for Drosophila photoreceptors.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
retrieved
8 April 2019
stated in
Drosophila atonal controls photoreceptor R8-specific properties and modulates both receptor tyrosine kinase and Hedgehog signalling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
hearing
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Genetically similar transduction mechanisms for touch and hearing in Drosophila.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
retrieved
8 April 2019
stated in
atonal is required for exoskeletal joint formation in the Drosophila auditory system
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
neuron recognition
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Genetic specification of axonal arbors: atonal regulates robo3 to position terminal branches in the Drosophila nervous system
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
sensory organ precursor cell fate determination
determination method
IDA
IMP
2 references
retrieved
8 April 2019
stated in
Functional distinctness of closely related transcription factors: a comparison of the Atonal and Amos proneural factors
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
retrieved
8 April 2019
stated in
The proneural gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous system
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IDA
cell differentiation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P48987
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IEA
cell fate commitment
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The control of cell fate in the embryonic visual system by atonal, tailless and EGFR signaling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
male courtship behavior, veined wing generated song production
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Song production in auditory mutants of Drosophila : the role of sensory feedback
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
positive regulation of transcription by RNA polymerase II
determination method
IEP
1 reference
retrieved
8 April 2019
stated in
The proneural proteins Atonal and Scute regulate neural target genes through different E-box binding sites
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IEP
antennal morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Distal-less and homothorax regulate multiple targets to pattern the Drosophila antenna.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
antennal joint morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
atonal is required for exoskeletal joint formation in the Drosophila auditory system
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48987
determination method
IMP
has part(s)
Myc-type, basic helix-loop-helix (bHLH) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P48987
Identifiers
RefSeq protein ID
NP_731223
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
40975
UniProt protein ID
P48987
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P48987
Ensembl protein ID
FBpp0081318
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0081318
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