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Oskar Dmel_CG10901
Protein found in Drosophila melanogaster
osk-PC
osk-PA
CG10901-PD
CG10901 gene product from transcript CG10901-RC
oskar
osk
CG10901-PA
dmoskar
CG10901-PC
osk-PD
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25158
part of
SGNH hydrolase superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P25158
OST-HTH/LOTUS domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
OSK domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25158
encoded by
osk
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25158
molecular function
mRNA binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The Crystal Structure of the Drosophila Germline Inducer Oskar Identifies Two Domains with Distinct Vasa Helicase- and RNA-Binding Activities
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IDA
cell component
cell cortex
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Translational activation of oskar mRNA: reevaluation of the role and importance of a 5' regulatory element [corrected].
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IDA
P granule
determination method
IDA
TAS
4 references
retrieved
8 April 2019
stated in
Germ cell development in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
retrieved
8 April 2019
stated in
Assembly of the Drosophila germ plasm
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
retrieved
8 April 2019
stated in
Oskar protein interaction with Vasa represents an essential step in polar granule assembly
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IDA
retrieved
8 April 2019
stated in
Phase transitioned nuclear Oskar promotes cell division of primordial germ cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IDA
pole plasm
determination method
TAS
2 references
retrieved
8 April 2019
stated in
Translational regulation and RNA localization in Drosophila oocytes and embryos.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
retrieved
8 April 2019
stated in
Transcriptional silencing and translational control: key features of early germline development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
cytoplasm
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Phase transitioned nuclear Oskar promotes cell division of primordial germ cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IDA
germ cell nucleus
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Phase transitioned nuclear Oskar promotes cell division of primordial germ cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IDA
posterior cell cortex
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Phase transitioned nuclear Oskar promotes cell division of primordial germ cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IDA
biological process
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P25158
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IEA
pole cell formation
determination method
TAS
2 references
retrieved
8 April 2019
stated in
Germ cell development in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
retrieved
8 April 2019
stated in
Translational regulation and RNA localization in Drosophila oocytes and embryos.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
germ cell development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A translation-independent role of oskar RNA in early Drosophila oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
oocyte anterior/posterior axis specification
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
p38 MAPK signalling cascades: ancient roles and new functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
NAS
pole plasm assembly
determination method
TAS
5 references
retrieved
8 April 2019
stated in
The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
retrieved
8 April 2019
stated in
Assembly of the Drosophila germ plasm
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
retrieved
8 April 2019
stated in
Structure and function of the egg cortex from oogenesis through fertilization.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
retrieved
8 April 2019
stated in
Two distinct mechanisms localise cyclin B transcripts in syncytial Drosophila embryos
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
retrieved
8 April 2019
stated in
Germ cell development in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
pole plasm protein localization
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Oskar protein interaction with Vasa represents an essential step in polar granule assembly
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
posterior abdomen determination
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A translation-independent role of oskar RNA in early Drosophila oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
long-term memory
determination method
IMP
TAS
2 references
retrieved
1 January 2018
stated in
RNA and memory: from feeding to localization
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25158&geneProductId=UniProtKB:P25158
determination method
TAS
retrieved
1 January 2018
stated in
The staufen/pumilio pathway is involved in Drosophila long-term memory.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25158&geneProductId=UniProtKB:P25158
determination method
IMP
visual behavior
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Shared visual attention and memory systems in the Drosophila brain
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
oocyte microtubule cytoskeleton polarization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
An oskar-dependent positive feedback loop maintains the polarity of the Drosophila oocyte
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
visual learning
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Shared visual attention and memory systems in the Drosophila brain
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
anterior/posterior axis specification, embryo
determination method
TAS
1 reference
retrieved
1 January 2018
stated in
The polarisation of the anteroposterior axis in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25158&geneProductId=UniProtKB:P25158
determination method
TAS
pole plasm mRNA localization
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Transcriptional silencing and translational control: key features of early germline development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
P granule organization
determination method
IMP
TAS
2 references
retrieved
8 April 2019
stated in
Structure and function of the egg cortex from oogenesis through fertilization.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
retrieved
8 April 2019
stated in
Live imaging of nuage and polar granules: evidence against a precursor-product relationship and a novel role for Oskar in stabilization of polar granule components
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
segmentation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Translational activation of oskar mRNA: reevaluation of the role and importance of a 5' regulatory element [corrected].
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
thermosensory behavior
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
cAMP signalling in mushroom bodies modulates temperature preference behaviour in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
regulation of mRNA stability
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Oskar allows nanos mRNA translation in Drosophila embryos by preventing its deadenylation by Smaug/CCR4.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
positive regulation of translation
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Translational repressors in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
NAS
regulation of oskar mRNA translation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
oogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A translation-independent role of oskar RNA in early Drosophila oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
long-term memory
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
RNA and memory: from feeding to localization
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
TAS
protein localization to nucleus
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Phase transitioned nuclear Oskar promotes cell division of primordial germ cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
P granule assembly
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Phase transitioned nuclear Oskar promotes cell division of primordial germ cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25158
determination method
IMP
has part(s)
OSK domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P25158
OST-HTH/LOTUS domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P25158
Identifiers
RefSeq protein ID
NP_731295
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
41066
NP_996186
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
41066
UniProt protein ID
P25158
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25158
Ensembl protein ID
FBpp0081435
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0081435
FBpp0089372
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0089372
Sitelinks
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Wikiquote
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