(Q29810481)

English

Enhancer of split malpha, Bearded family member Dmel_CG8337

Protein found in Drosophila melanogaster

E(spl)malpha-BFM
enhancer of split malpha, bearded family member
CG8337 gene product from transcript CG8337-RA
E(spl)malpha-BFM-PA
E(spl)malpha
E(spl) region transcript malpha
CG8337-PA

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Statements

1 reference

25 May 2022

Enhancer of split M4 family

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O97178

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

10 September 2018

Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97178&geneProductId=UniProtKB:O97178

determination method

IPI

ubiquitin protein ligase binding

1 reference

16 July 2018

Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97178&geneProductId=UniProtKB:O97178

determination method

IPI

ubiquitin protein ligase binding

3 references

8 April 2019

Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97178

8 April 2019

Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97178

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97178

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97178

determination method

ND

biological process

cell fate specification

1 reference

16 July 2018

Antagonism of notch signaling activity by members of a novel protein family encoded by the bearded and enhancer of split gene complexes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97178&geneProductId=UniProtKB:O97178

determination method

IMP

Notch signaling pathway

3 references

16 July 2018

Antagonism of notch signaling activity by members of a novel protein family encoded by the bearded and enhancer of split gene complexes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97178&geneProductId=UniProtKB:O97178

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97178&geneProductId=UniProtKB:O97178

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97178&geneProductId=UniProtKB:O97178

determination method

IEA

Notch signaling pathway

4 references

10 September 2018

Antagonism of notch signaling activity by members of a novel protein family encoded by the bearded and enhancer of split gene complexes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97178&geneProductId=UniProtKB:O97178

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97178&geneProductId=UniProtKB:O97178

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97178&geneProductId=UniProtKB:O97178

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97178&geneProductId=UniProtKB:O97178

determination method

IBA

sensory organ development

3 references

8 April 2019

Overexpression of the m4 and malpha genes of the E(spl)-complex antagonizes notch mediated lateral inhibition.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97178

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97178

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97178

determination method

IBA

Notch signaling pathway

determination method

IBA

IEA

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

(Q29810481)

Enhancer of split malpha, Bearded family member Dmel_CG8337

Statements

Identifiers

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