(Q37476366)

English

Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta

scientific article published on 04 July 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Enhancer of split m4, Bearded family member Dmel_CG6099

1 reference

GOA release 2020-03-11

Neuralized Dmel_CG11988

1 reference

GOA release 2020-03-11

Enhancer of split malpha, Bearded family member Dmel_CG8337

1 reference

GOA release 2020-03-11

author name string

Joseph R Fontana

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

James W Posakony

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

language of work or name

0 references

publication date

4 July 2009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Developmental Biology

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

333

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

373-385

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Origin and diversification of the basic helix-loop-helix gene family in metazoans: insights from comparative genomics

1 reference

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23 August 2017

Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis

1 reference

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23 August 2017

The Enhancer of split and Achaete-Scute complexes of Drosophilids derived from simple ur-complexes preserved in mosquito and honeybee

1 reference

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23 August 2017

Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs

1 reference

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23 August 2017

GenePalette: a universal software tool for genome sequence visualization and analysis

1 reference

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23 August 2017

The roles of cis-inactivation by Notch ligands and of neuralized during eye and bristle patterning in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

23 August 2017

Identification of Drosophila MicroRNA targets

1 reference

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23 August 2017

A protein interaction map of Drosophila melanogaster

1 reference

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23 August 2017

Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation

1 reference

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23 August 2017

Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta

1 reference

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23 August 2017

Characterizing Class I WW domains defines key specificity determinants and generates mutant domains with novel specificities

1 reference

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23 August 2017

The probability of duplicate gene preservation by subfunctionalization

1 reference

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23 August 2017

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1 reference

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23 August 2017

Genetic Transformation of Drosophila with Transposable Element Vectors

1 reference

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23 August 2017

Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators

1 reference

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6 September 2017

The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

6 September 2017

Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

28 September 2017

The enhancer of split complex of Drosophila includes four Notch-regulated members of the bearded gene family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

26 June 2018

The K box, a conserved 3' UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

26 June 2018

The Drosophila gene Bearded encodes a novel small protein and shares 3' UTR sequence motifs with multiple Enhancer of split complex genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

26 June 2018

Gain-of-function alleles of Bearded interfere with alternative cell fate decisions in Drosophila adult sensory organ development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

26 June 2018

Dorsal-ventral pattern of Delta trafficking is established by a Snail-Tom-Neuralized pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

2 September 2018

Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

2 September 2018

Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of Hairless

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

2 September 2018

Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

2 September 2018

Affinity purification of GST fusion proteins for immunohistochemical studies of gene expression.

1 reference

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2 September 2018

neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

2 September 2018

neuralized functions cell-autonomously to regulate a subset of notch-dependent processes during adult Drosophila development.

1 reference

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2 September 2018

Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division.

1 reference

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2 September 2018

GFP and beta-galactosidase transformation vectors for promoter/enhancer analysis in Drosophila

1 reference

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2 September 2018

Barbu: an E(spl) m4/m(alpha)-related gene that antagonizes Notch signaling and is required for the establishment of ommatidial polarity

1 reference

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2 September 2018

Antagonism of notch signaling activity by members of a novel protein family encoded by the bearded and enhancer of split gene complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

2 September 2018

Overexpression of the m4 and malpha genes of the E(spl)-complex antagonizes notch mediated lateral inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

2 September 2018

The Bearded box, a novel 3' UTR sequence motif, mediates negative post-transcriptional regulation of Bearded and Enhancer of split Complex gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

2 September 2018

Persistent expression of genes of the enhancer of split complex suppresses neural development in Drosophila.

1 reference

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2 September 2018

Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signaling

1 reference

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2 September 2018

Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

2 September 2018

The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793682

2 September 2018

Suppressor of hairless, the Drosophila homologue of RBP-J kappa, transactivates the neurogenic gene E(spl)m8.

1 reference

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2 September 2018

Identifiers

10.1016/J.YDBIO.2009.06.039

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

0 references

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