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SHC-adaptor protein Dmel_CG3715
Protein found in Drosophila melanogaster
CG3715 gene product from transcript CG3715-RA
CG3715-PA
SHC adaptor protein
Shc-PA
SHC-adaptor protein
Shc
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3C8
part of
PH-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3C8
SH2 domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3C8
SH2 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Phosphotyrosine interaction domain, Shc-like, protein family
1 reference
based on heuristic
inferred from protein domain or family
SH2 adaptor protein C, SH2 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
PTB/PI domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3C8
encoded by
Shc
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3C8
molecular function
receptor tyrosine kinase binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IBA
epidermal growth factor receptor binding
determination method
IDA
2 references
retrieved
9 May 2019
stated in
Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IDA
retrieved
9 May 2019
stated in
A Drosophila shc gene product is implicated in signaling by the DER receptor tyrosine kinase
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IDA
receptor tyrosine kinase binding
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IBA
cell component
intracellular anatomical structure
determination method
IEA
1 reference
retrieved
10 September 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3C8&geneProductId=UniProtKB:Q9V3C8
determination method
IEA
plasma membrane
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IBA
biological process
epidermal growth factor receptor signaling pathway
determination method
IGI
1 reference
retrieved
1 January 2018
stated in
The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3C8&geneProductId=UniProtKB:Q9V3C8
determination method
IGI
tracheal outgrowth, open tracheal system
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
torso signaling pathway
determination method
IGI
1 reference
retrieved
9 May 2019
stated in
The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IGI
melanotic encapsulation of foreign target
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
A directed miniscreen for genes involved in the Drosophila anti-parasitoid immune response
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
intracellular signal transduction
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IEA
TORC1 signaling
determination method
IMP
1 reference
retrieved
16 July 2018
stated in
Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3C8&geneProductId=UniProtKB:Q9V3C8
determination method
IMP
compound eye photoreceptor cell differentiation
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
epidermal growth factor receptor signaling pathway
determination method
IDA
IGI
3 references
retrieved
10 September 2018
stated in
The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3C8&geneProductId=UniProtKB:Q9V3C8
determination method
IGI
retrieved
10 September 2018
stated in
A Drosophila shc gene product is implicated in signaling by the DER receptor tyrosine kinase
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3C8&geneProductId=UniProtKB:Q9V3C8
determination method
IDA
retrieved
10 September 2018
stated in
Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V3C8&geneProductId=UniProtKB:Q9V3C8
determination method
IDA
terminal region determination
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
imaginal disc-derived wing vein specification
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
dorsal/ventral axis specification, ovarian follicular epithelium
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
regulation of dorsal/ventral axon guidance
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
epithelial cell migration, open tracheal system
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
mesodermal cell migration
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
FGF signalling and the mechanism of mesoderm spreading in Drosophila embryos
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
fibroblast growth factor receptor signaling pathway
determination method
IMP
2 references
retrieved
9 May 2019
stated in
FGF signalling and the mechanism of mesoderm spreading in Drosophila embryos
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
retrieved
9 May 2019
stated in
Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
vascular endothelial growth factor receptor signaling pathway
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
positive regulation of TORC1 signaling
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
epidermal growth factor receptor signaling pathway
determination method
IDA
IGI
IMP
4 references
retrieved
9 May 2019
stated in
Two distinct modes of guidance signalling during collective migration of border cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
retrieved
9 May 2019
stated in
The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IGI
retrieved
9 May 2019
stated in
Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IDA
retrieved
9 May 2019
stated in
A Drosophila shc gene product is implicated in signaling by the DER receptor tyrosine kinase
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IDA
border follicle cell migration
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Two distinct modes of guidance signalling during collective migration of border cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IMP
positive regulation of cell population proliferation
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IEA
stem cell differentiation
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V3C8
determination method
IEA
has part(s)
PTB/PI domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3C8
Phosphotyrosine interaction domain, Shc-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3C8
SH2 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3C8
SH2 adaptor protein C, SH2 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V3C8
Identifiers
RefSeq protein ID
NP_524683
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
44052
UniProt protein ID
Q9V3C8
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V3C8
Ensembl protein ID
FBpp0076186
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0076186
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