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Dj-1beta Dmel_CG1349
Protein found in Drosophila melanogaster
CG1349 gene product from transcript CG1349-RB
DJ-1B
dj-1beta
CG1349-PB
dj-1beta-PB
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VA37
part of
Protein/nucleic acid deglycase DJ-1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VA37
Class I glutamine amidotransferase-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VA37
DJ-1/PfpI domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VA37
encoded by
dj-1beta
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VA37
molecular function
protein deglycase activity
determination method
ISS
1 reference
retrieved
27 March 2018
stated in
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VA37&geneProductId=UniProtKB:Q9VA37
determination method
ISS
protein deglycase activity
determination method
IBA
ISS
2 references
retrieved
8 April 2019
stated in
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
ISS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IBA
oxidoreductase activity, acting on peroxide as acceptor
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
ISS
cell component
mitochondrion
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VA37&geneProductId=UniProtKB:Q9VA37
determination method
IEA
nucleus
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IBA
cytosol
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IBA
biological process
protein deglycosylation
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Evidence Against a Role for the Parkinsonism-associated Protein DJ-1 in Methylglyoxal Detoxification
GOA
curator
UniProt
UniProt protein ID
Q9VA37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IDA
response to oxidative stress
determination method
IDA
IMP
6 references
retrieved
8 April 2019
stated in
Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
retrieved
8 April 2019
stated in
Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
retrieved
8 April 2019
stated in
Drosophila DJ-1 decreases neural sensitivity to stress by negatively regulating Daxx-like protein through dFOXO.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
retrieved
8 April 2019
stated in
Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
retrieved
8 April 2019
stated in
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
retrieved
8 April 2019
stated in
Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IDA
adult locomotory behavior
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
methylglyoxal metabolic process
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Evidence Against a Role for the Parkinsonism-associated Protein DJ-1 in Methylglyoxal Detoxification
GOA
curator
UniProt
UniProt protein ID
Q9VA37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IDA
protein deglycation, methylglyoxal removal
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Evidence Against a Role for the Parkinsonism-associated Protein DJ-1 in Methylglyoxal Detoxification
GOA
curator
UniProt
UniProt protein ID
Q9VA37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IDA
negative regulation of developmental growth
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
dj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
regulation of hydrogen peroxide metabolic process
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
dj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
regulation of mitochondrial ATP synthesis coupled electron transport
determination method
IGI
1 reference
retrieved
8 April 2019
stated in
DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IGI
protein deglycation
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VA37&geneProductId=UniProtKB:Q9VA37
determination method
IEA
protein deglycation, glyoxal removal
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IBA
guanine deglycation, glyoxal removal
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IBA
larval locomotory behavior
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Reactive oxygen species regulate activity-dependent neuronal plasticity in
GOA
curator
UniProt
UniProt protein ID
Q9VA37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
phosphatidylinositol 3-kinase signaling
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Reactive oxygen species regulate activity-dependent neuronal plasticity in
GOA
curator
UniProt
UniProt protein ID
Q9VA37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
cellular response to reactive oxygen species
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Reactive oxygen species regulate activity-dependent neuronal plasticity in
GOA
curator
UniProt
UniProt protein ID
Q9VA37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
regulation of synaptic plasticity
determination method
IGI
IMP
2 references
retrieved
8 April 2019
stated in
Reactive oxygen species regulate activity-dependent neuronal plasticity in
GOA
curator
UniProt
UniProt protein ID
Q9VA37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
retrieved
8 April 2019
stated in
Reactive oxygen species regulate activity-dependent neuronal plasticity in
GOA
curator
UniProt
UniProt protein ID
Q9VA37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IGI
regulation of neuromuscular synaptic transmission
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Reactive oxygen species regulate activity-dependent neuronal plasticity in
GOA
curator
UniProt
UniProt protein ID
Q9VA37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VA37
determination method
IMP
has part(s)
DJ-1/PfpI
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VA37
Identifiers
RefSeq protein ID
NP_651825
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
43652
UniProt protein ID
Q9VA37
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VA37
Ensembl protein ID
FBpp0401456
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0401456
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