(Q28596604)

1 February 2017

title

Evidence Against a Role for the Parkinsonism-associated Protein DJ-1 in Methylglyoxal Detoxification (English)

1 reference

Parkinsonism associated deglycase

1 February 2017

main subject

1 reference

protein deglycation, methylglyoxal removal

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Dj-1beta Dmel_CG1349

1 reference

GOA release 2020-03-11

2 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27903648%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

3

Peter Nawroth

2 references

1 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27903648%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Thomas Fleming

series ordinal

2

2 references

1 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27903648%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Daniel H Pfaff

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27903648%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

language of work or name

English

0 references

publication date

13 January 2017

1 reference

Journal of Biological Chemistry

1 February 2017

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

2 references

1 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27903648%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

292

2 references

1 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27903648%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

2

2 references

1 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27903648%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

685-690

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27903648%20AND%20SRC:MED&resulttype=core&format=json

The Role of Oxidative Stress in Neurodegenerative Diseases

6 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

Cross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for Cancer

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

Human DJ-1 and its homologs are novel glyoxalases

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation

17 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

17 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems--role in ageing and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

Methylglyoxal comes of AGE.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5241742

Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds.

29 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.743823

Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.743823

Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.743823

Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.743823

Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.743823

The DJ-1 superfamily member Hsp31 repairs proteins from glycation by methylglyoxal and glyoxal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.743823

Oral administration of methylglyoxal leads to kidney collagen accumulation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.743823

Mitochondrial Regulation by PINK1-Parkin Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.743823

21 January 2018

Identifiers

DOI

10.1074/JBC.M116.743823

2 references

1 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27903648%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27903648%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

2 references

1 February 2017