(Q58905388)

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Toxin-induced and genetic animal models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The pathways of mitophagy for quality control and clearance of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Autoregulation of Parkin activity through its ubiquitin-like domain

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Loss of locus coeruleus neurons and reduced startle in parkin null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The PINK1/Parkin pathway regulates mitochondrial morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin interacts with Ambra1 to induce mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

p32 regulates mitochondrial morphology and dynamics through parkin.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Atg32 is a mitochondrial protein that confers selectivity during mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

BNIP3 subfamily BH3-only proteins: mitochondrial stress sensors in normal and pathological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Essential role for Nix in autophagic maturation of erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Nix is a selective autophagy receptor for mitochondrial clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

NIX is required for programmed mitochondrial clearance during reticulocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Possible existence of lysosome-like organella within mitochondria and its role in mitochondrial quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin mono-ubiquitinates Bcl-2 and regulates autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

PINK1 cleavage at position A103 by the mitochondrial protease PARL.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The kinase domain of mitochondrial PINK1 faces the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Cell type-specific upregulation of Parkin in response to ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin attenuates manganese-induced dopaminergic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Induction of parkin expression in the presence of oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Characterization of FRA6E and its potential role in autosomal recessive juvenile parkinsonism and ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Alterations in the common fragile site gene Parkin in ovarian and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin gene alterations in ovarian carcinoma from northern Indian population

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Abnormal methylation of the common PARK2 and PACRG promoter is associated with downregulation of gene expression in acute lymphoblastic leukemia and chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Attenuation of proteolysis-mediated cyclin E regulation by alternatively spliced Parkin in human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Alterations of the tumor suppressor gene Parkin in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin as a tumor suppressor gene for hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin gene alterations in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

A protein interaction map of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

DJ-1 has a role in antioxidative stress to prevent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Sequencing analysis of OMI/HTRA2 shows previously reported pathogenic mutations in neurologically normal controls

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The serine protease HtrA2/Omi cleaves Parkin and irreversibly inactivates its E3 ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Neurodegeneration in mnd2 mutant mice is not prevented by parkin transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Genetic mouse models for Parkinson's disease display severe pathology in glial cell mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Genetic Screening of the Mitochondrial Rho GTPases MIRO1 and MIRO2 in Parkinson's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

MFN2 mutation distribution and genotype/phenotype correlation in Charcot-Marie-Tooth type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio).

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Reduction of protein translation and activation of autophagy protect against PINK1 pathogenesis in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial defect and PGC-1α dysfunction in parkin-associated familial Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The MAPK1/3 pathway is essential for the deregulation of autophagy observed in G2019S LRRK2 mutant fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

LRRK2 as a modulator of lysosomal calcium homeostasis with downstream effects on autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Deficiency of ATP13A2 leads to lysosomal dysfunction, α-synuclein accumulation, and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Loss of nuclear activity of the FBXO7 protein in patients with parkinsonian-pyramidal syndrome (PARK15)

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Alpha-synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Cellular co-localization of phosphorylated tau- and NACP/alpha-synuclein-epitopes in lewy bodies in sporadic Parkinson's disease and in dementia with Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Alpha-Synuclein contributes to GSK-3beta-catalyzed Tau phosphorylation in Parkinson's disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Genome-wide association study reveals genetic risk underlying Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160

Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.5402%2F2012%2F926160