(Q46131495)

19 December 2017

title

Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response (English)

1 reference

19 December 2017

author

Valentina Fedele

3

1 reference

19 December 2017

Alan Renton

6

1 reference

19 December 2017

Nicholas W. Wood

12

1 reference

19 December 2017

Julian Downward

13

1 reference

19 December 2017

author name string

N Moisoi

1

1 reference

19 December 2017

K Klupsch

2

1 reference

19 December 2017

P East

4

1 reference

19 December 2017

S Sharma

5

1 reference

19 December 2017

H Plun-Favreau

7

1 reference

19 December 2017

R E Edwards

8

1 reference

19 December 2017

P Teismann

9

1 reference

19 December 2017

M D Esposti

10

1 reference

19 December 2017

A D Morrison

11

1 reference

19 December 2017

L M Martins

14

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19 December 2017

publication date

21 November 2008

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19 December 2017

Cell Death & Differentiation

published in

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19 December 2017

volume

16

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19 December 2017

issue

3

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19 December 2017

page(s)

449-464

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19 December 2017

https://scigraph.springernature.com/pub.10.1038/cdd.2008.166

exact match

0 references

cites work

Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

The mitochondrial death squad: hardened killers or innocent bystanders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

OMP peptide signals initiate the envelope-stress response by activating DegS protease via relief of inhibition mediated by its PDZ domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

A mitochondrial specific stress response in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Staging of brain pathology related to sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Membrane lipids and cell death: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: a mechanism for hypoxia-dependent effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Oxidative stress-triggered unfolded protein response is upstream of intrinsic cell death evoked by parkinsonian mimetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Sensing external stress: watchdogs of the Escherichia coli cell envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Lipid peroxidation as cause of nigral cell death in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Genes associated with pro-apoptotic and protective mechanisms are affected differently on exposure of neuronal cell cultures to arsenite. No indication for endoplasmic reticulum stress despite activation of grp78 and gadd153 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

IRE1 signaling affects cell fate during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Cardiolipin and its metabolites move from mitochondria to other cellular membranes during death receptor-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Tumor necrosis factor-related apoptosis-inducing ligand alters mitochondrial membrane lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Summaries of Affymetrix GeneChip probe level data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Bioconductor: open software development for computational biology and bioinformatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

inferred from DOI database lookup

7 January 2021

based on heuristic

Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.166

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/CDD.2008.166

1 reference

19 December 2017

Dimensions Publication ID

0 references

1 reference

19 December 2017