(Q28258706)

Nucleotide dependent motion and mechanism of action of p97/VCP

21 April 2017

1 reference

UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

21 April 2017

1 reference

p47 is a cofactor for p97-mediated membrane fusion

21 April 2017

1 reference

A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways

21 April 2017

1 reference

VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments

21 April 2017

1 reference

Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation

21 April 2017

1 reference

Ubx2 links the Cdc48 complex to ER-associated protein degradation

21 April 2017

1 reference

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

21 April 2017

1 reference

Hierarchical binding of cofactors to the AAA ATPase p97

21 April 2017

1 reference

Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.

21 April 2017

1 reference

Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

21 April 2017

1 reference

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

21 April 2017

1 reference

Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation

21 April 2017

1 reference

Cdc48/p97 mediates UV-dependent turnover of RNA Pol II.

21 April 2017

1 reference

A ubiquitin-selective AAA-ATPase mediates transcriptional switching by remodelling a repressor-promoter DNA complex

21 April 2017

1 reference

The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover

21 April 2017

1 reference

A stress-responsive system for mitochondrial protein degradation

21 April 2017

1 reference

Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro

21 April 2017

1 reference

Inhibition of p97-dependent protein degradation by Eeyarestatin I

21 April 2017

1 reference

The role of a novel p97/valosin-containing protein-interacting motif of gp78 in endoplasmic reticulum-associated degradation

21 April 2017

1 reference

The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

21 April 2017

1 reference

Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone

21 April 2017

1 reference

Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3

21 April 2017

1 reference

The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER

21 April 2017

1 reference

Defining the human deubiquitinating enzyme interaction landscape

21 April 2017

1 reference

ERAD: the long road to destruction

21 April 2017

1 reference

An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis

21 April 2017

1 reference

VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

21 April 2017

1 reference

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

21 April 2017

1 reference

Cdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagy

21 April 2017

1 reference

Cdc48/p97 and Shp1/p47 regulate autophagosome biogenesis in concert with ubiquitin-like Atg8

21 April 2017

1 reference

Valosin-containing protein, VCP, is a ubiquitous clathrin-binding protein

21 April 2017

1 reference

DOA1/UFD3 plays a role in sorting ubiquitinated membrane proteins into multivesicular bodies

21 April 2017

1 reference

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

21 April 2017

1 reference

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

21 April 2017

1 reference

The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis

21 April 2017

1 reference

The AAA-ATPase Cdc48 and cofactor Shp1 promote chromosome bi-orientation by balancing Aurora B activity

21 April 2017

1 reference

Chromosome alignment and segregation regulated by ubiquitination of survivin

21 April 2017

1 reference

VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells

21 April 2017

1 reference

Exome sequencing reveals VCP mutations as a cause of familial ALS

21 April 2017

1 reference

A novel ATP-dependent conformation in p97 N–D1 fragment revealed by crystal structures of disease-related mutants

21 April 2017

1 reference

Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation

21 April 2017

1 reference

Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation

21 April 2017

1 reference

Imbalances in p97 co-factor interactions in human proteinopathy

21 April 2017

1 reference

Autophagosome formation: core machinery and adaptations

21 April 2017

1 reference

Evolutionary relationships and structural mechanisms of AAA+ proteins

21 April 2017

1 reference

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

21 April 2017

1 reference

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

21 April 2017

1 reference

Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation

21 April 2017

1 reference

12 December 2020

Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion

1 reference

12 December 2020

Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations

1 reference

12 December 2020

VCP associated inclusion body myopathy and paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease

1 reference

12 December 2020

Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone

1 reference

12 December 2020

Going through the motions: The ATPase cycle of p97

1 reference

12 December 2020

Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate

1 reference

12 December 2020

Valosin-containing protein phosphorylation at Ser784 in response to DNA damage

1 reference

12 December 2020

Ubiquitin-proteasome system and mitochondria - reciprocity

1 reference

12 December 2020

Mitochondria get a Parkin' ticket

1 reference

12 December 2020

p97 ATPase, an ATPase involved in membrane fusion, interacts with DNA unwinding factor (DUF) that functions in DNA replication

1 reference

12 December 2020

VCP disease associated with myopathy, Paget disease of bone and frontotemporal dementia: review of a unique disorder

1 reference

12 December 2020

A conserved unfoldase activity for the p97 AAA-ATPase in proteasomal degradation

1 reference

12 December 2020

Cdc48/p97-Ufd1-Npl4 antagonizes Aurora B during chromosome segregation in HeLa cells.

1 reference

12 December 2020

Golgi reassembly after mitosis: the AAA family meets the ubiquitin family

1 reference

12 December 2020

Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?

1 reference

12 December 2020

The p97 ATPase associates with EEA1 to regulate the size of early endosomes

1 reference

12 December 2020

Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates.

1 reference

12 December 2020

Cdc48p is required for the cell cycle commitment point at Start via degradation of the G1-CDK inhibitor Far1p

1 reference

12 December 2020

Degradation-linked ubiquitin signal and proteasome are integral components of DNA double strand break repair: New perspectives for anti-cancer therapy.

1 reference

12 December 2020

Bod1, a novel kinetochore protein required for chromosome biorientation

1 reference

12 December 2020

Insights into adaptor binding to the AAA protein p97.

1 reference

12 December 2020

How do ESCRT proteins control autophagy?

1 reference

12 December 2020

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

1 reference

12 December 2020

Caenorhabditis elegans p97/CDC-48 is crucial for progression of meiosis I.

1 reference

12 December 2020

Enhanced ATPase activities as a primary defect of mutant valosin-containing proteins that cause inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia

1 reference

12 December 2020

Capturing VCP: another molecular piece in the ALS jigsaw puzzle

1 reference

12 December 2020

p97/VCP at the intersection of the autophagy and the ubiquitin proteasome system

1 reference

12 December 2020

E3 ubiquitin ligases and mitosis: embracing the complexity.

1 reference

12 December 2020

p97-containing complexes in proliferation control and cancer: emerging culprits or guilt by association?

1 reference

12 December 2020

A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction.

1 reference

12 December 2020

Delivery of ubiquitinated substrates to protein-unfolding machines

1 reference

12 December 2020

CDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication

1 reference

12 December 2020

An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF.

1 reference

12 December 2020

Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin

1 reference

12 December 2020

The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis

1 reference

12 December 2020

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

1 reference

12 December 2020

VCIP135 deubiquitinase and its binding protein, WAC, in p97ATPase-mediated membrane fusion

1 reference

12 December 2020

Characterization of the aggregation-prevention activity of p97/valosin-containing protein

1 reference

12 December 2020

Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly.

1 reference

12 December 2020

Cdc48: a power machine in protein degradation

1 reference

12 December 2020

The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy

1 reference

12 December 2020

The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism

1 reference

12 December 2020

Cell cycle progression requires the CDC-48UFD-1/NPL-4 complex for efficient DNA replication

1 reference

12 December 2020

The complexities of p97 function in health and disease

1 reference

12 December 2020

Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1.

1 reference

12 December 2020

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

1 reference

12 December 2020

p97 Homologs from Caenorhabditis elegans, CDC-48.1 and CDC-48.2, suppress the aggregate formation of huntingtin exon1 containing expanded polyQ repeat

1 reference

12 December 2020

The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks.

1 reference

12 December 2020

Caenorhabditis elegans p97 controls germline-specific sex determination by controlling the TRA-1 level in a CUL-2-dependent manner.

1 reference

12 December 2020

Cdc48p(Npl4p/Ufd1p) binds and segregates membrane-anchored/tethered complexes via a polyubiquitin signal present on the anchors

1 reference

12 December 2020