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Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.
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Europe PubMed Central
PMC publication ID
3386132
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
title
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
main subject
Parkinson's disease
1 reference
based on heuristic
inferred from title
neurodegeneration
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based on heuristic
inferred from title
author
Benjamin Dehay
series ordinal
1
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Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Alfredo Ramirez
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2
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Europe PubMed Central
PMC publication ID
3386132
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
Marta Martinez-vicente
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3
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Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
Marie-Hélène Canron
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5
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Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
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2 February 2020
Evelyne Doudnikoff
series ordinal
6
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Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Miquel Vila
series ordinal
8
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Europe PubMed Central
PMC publication ID
3386132
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Erwan Bezard
series ordinal
10
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Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Anne Vital
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7
object named as
Anne Vital
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Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Christine Klein
series ordinal
9
object named as
Christine Klein
1 reference
stated in
Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
author name string
Celine Perier
series ordinal
4
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Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
language of work or name
English
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publication date
30 May 2012
1 reference
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Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
volume
109
1 reference
stated in
Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
issue
24
1 reference
stated in
Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
page(s)
9611-9616
1 reference
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Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
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Mutant Atp13a2 proteins involved in parkinsonism are degraded by ER-associated degradation and sensitize cells to ER-stress induced cell death
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Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism
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Pathogenic lysosomal depletion in Parkinson's disease
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Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disorders
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Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo
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Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
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2 October 2017
Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species
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2 October 2017
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2 October 2017
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23 September 2018
Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.
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23 September 2018
In search of an "autophagomometer".
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386132
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23 September 2018
α-Synuclein Is Degraded by Both Autophagy and the Proteasome
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23 September 2018
Lysosomal membrane permeabilization in Parkinson disease
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22647602
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Etiology and pathogenesis of Parkinson's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22647602
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Defective acidification of intracellular organelles results in aberrant secretion of cathepsin D in cancer cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22647602
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.1112368109
1 reference
stated in
Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
ADS bibcode
2012PNAS..109.9611D
0 references
PMC publication ID
3386132
1 reference
stated in
Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
PubMed publication ID
22647602
1 reference
stated in
Europe PubMed Central
PMC publication ID
3386132
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22647602%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
ResearchGate publication ID
235615444
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