Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q29547424)
Watch
English
Parkinson's disease: mechanisms and models
scientific article (publication date: 11 September 2003)
In more languages
edit
Statements
instance of
scholarly article
0 references
review article
1 reference
stated in
Europe PubMed Central
title
Parkinson's disease: mechanisms and models
(English)
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12971891
retrieved
23 April 2017
main subject
Parkinson's disease
1 reference
based on heuristic
inferred from title
author
Serge Przedborski
series ordinal
2
object named as
Przedborski S
1 reference
stated in
PubMed
retrieved
23 April 2017
author name string
Dauer W
series ordinal
1
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12971891
retrieved
23 April 2017
language of work or name
English
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12971891
retrieved
23 April 2017
publication date
11 September 2003
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12971891
retrieved
23 April 2017
published in
Neuron
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12971891
retrieved
23 April 2017
volume
39
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12971891
retrieved
23 April 2017
page(s)
889-909
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12971891
retrieved
23 April 2017
issue
6
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12971891
retrieved
23 April 2017
cites work
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The free radical theory of aging matures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase inhibitors attenuate 1-methyl-4-phenylpyridinium toxicity in primary cultures of mesencephalic dopaminergic neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Residual structure and dynamics in Parkinson's disease-associated mutants of alpha-synuclein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Failure to find the alpha-synuclein gene missense mutation (G209A) in 100 patients with younger onset Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress, mitochondrial respiration, and Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selectivity of the parkinsonian neurotoxin MPTP: toxic metabolite MPP+ binds to neuromelanin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Energy thresholds in brain mitochondria. Potential involvement in neurodegeneration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic parkinsonism secondary to intravenous injection of meperidine analogues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mechanism of paraquat toxicity involving nitric oxide synthase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformational properties of alpha-synuclein in its free and lipid-associated states
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
alpha-synuclein gene haplotypes are associated with Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Drosophila model of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ageing and Parkinson's disease: substantia nigra regional selectivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuropathology of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Locus ceruleus lesions and eosinophilic inclusions in MPTP-treated monkeys.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional recovery in parkinsonian monkeys treated with GDNF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rat alpha-synuclein interacts with Tat binding protein 1, a component of the 26S proteasomal complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-synuclein and neurodegenerative diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complex I and Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subsets of midbrain dopaminergic neurons in monkeys are distinguished by different levels of mRNA for the dopamine transporter: comparison with the mRNA for the D2 receptor, tyrosine hydroxylase and calbindin immunoreactivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotoxicity of the meperidine analogue N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on brain catecholamine neurons in the mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased expression and redistribution of the antiapoptotic molecule Bcl-xL in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A dual effect of 1-methyl-4-phenylpyridinium (MPP+)-analogs on the respiratory chain of bovine heart mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evaluation of 50 probands with early-onset Parkinson's disease for Parkin mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partial lesions of the dopaminergic nigrostriatal system in rat brain: biochemical characterization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Sydney Multicentre Study of Parkinson's disease: a report on the first 3 years
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Does neuromelanin contribute to the vulnerability of catecholaminergic neurons in monkeys intoxicated with MPTP?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental cell death in dopaminergic neurons of the substantia nigra of mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specificity of dopaminergic neuronal degeneration induced by intracerebral injection of 6-hydroxydopamine in the nigrostriatal dopamine system.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds alpha-synuclein filaments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
6-Hydroxydopamine lesion of the rat substantia nigra: time course and morphology of cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenosine receptor antagonists potentiate dopamine receptor agonist-induced rotational behavior in 6-hydroxydopamine-lesioned rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accumulation of biological amines into chromaffin granules: a model for hormone and neurotransmitter transport
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemical neurotoxins as denervation tools in neurobiology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure/function of alpha-synuclein in health and disease: rational development of animal models for Parkinson's and related diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Redox cycling of MPP+: evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aggresomes, inclusion bodies and protein aggregation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ubiquitin pathway in Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No genetic association of the Ubiquitin Carboxy-terminal Hydrolase-L1 gene S18Y polymorphism with familial Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The association of incident dementia with mortality in PD.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age at onset in two common neurodegenerative diseases is genetically controlled
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkin-proven disease: common founders but divergent phenotypes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Environmental risk factors and Parkinson's disease: a case-control study in Taiwan
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene transfer of a reserpine-sensitive mechanism of resistance to N-methyl-4-phenylpyridinium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between early-onset Parkinson's disease and mutations in the parkin gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective lesion of central dopamine or noradrenaline neuron systems in the neonatal rat: motor behavior and monoamine alterations at adult stage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in substantia nigra following developmental striatal excitotoxic injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage in brain mitochondria caused by aging and MPTP treatment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Case-control study of the ubiquitin carboxy-terminal hydrolase L1 gene in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transport
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rate of cell death in parkinsonism indicates active neuropathological process
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dopamine transporters and neuronal injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkin and Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkinson disease survival: a population-based study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Catecholamine release and uptake in the mouse prefrontal cortex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Spanish familial Parkinson's disease and screening for the Ala53Thr mutation of the α-synuclein gene in early onset patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differences in nigral neuron number and sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57/bl and CD-1 mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isoquinoline neurotoxins in the brain and Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MPTP, MPP+ and mitochondrial function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased susceptibility to MPTP toxicity in middle-aged rhesus monkeys
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synucleins are a novel class of substrates for G protein-coupled receptor kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Programmed cell death and the control of cell survival: lessons from the nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Axonal self-destruction and neurodegeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subcellular compartmentalization of 1-methyl-4-phenylpyridinium with catecholamines in adrenal medullary chromaffin vesicles may explain the lack of toxicity to adrenal chromaffin cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of common marmosets.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CYP2D6 allelic frequencies in young-onset Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A polymorphic variation of serine to tyrosine at codon 18 in the ubiquitin C-terminal hydrolase-L1 gene is associated with a reduced risk of sporadic Parkinson's disease in a Japanese population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial complex I deficiency in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dose-dependent destruction of the coeruleus-cortical and nigral-striatal projections by MPTP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Carrier-mediated processes in blood--brain barrier penetration and neural uptake of paraquat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular localization of tyrosine hydroxylase mRNA and cholecystokinin mRNA-containing cells in the ventral mesencephalon of the common marmoset: effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The neurotoxin 1-methyl-4-phenylpyridinium is sequestered within neurons that contain the vesicular monoamine transporter.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An alternative, nonapoptotic form of programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical and pathological features of a parkinsonian syndrome in a family with an Ala53Thr ?-synuclein mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Origin and functional consequences of the complex I defect in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo labeling of mitochondrial complex I (NADH:ubiquinone oxidoreductase) in rat brain using [(3)H]dihydrorotenone.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epidemiology of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkinson disease in twins: an etiologic study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinson's disease?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkinson's disease: loss of neurons from the ventral tegmental area contralateral to therapeutic surgical lesions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dopamine transporter messenger RNA in Parkinson's disease and control substantia nigra neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
6-hydroxy-dopamine induced degeneration of central monoamine neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stereotaxic mapping of the monoamine pathways in the rat brain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuropathology in mice expressing human alpha-synuclein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic MPTP treatment reproduces in baboons the differential vulnerability of mesencephalic dopaminergic neurons observed in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting programmed cell death in neurodegenerative diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP) on monoamine neurotransmitters in mouse brain & heart
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of age on the passage of paraquat through the blood-brain barrier in rats: a distribution and pathological examination.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No changes in behaviour, nigro-striatal system neurochemistry or neuronal cell death following toxic multiple oral paraquat administration to rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age at onset of Parkinson disease and apolipoprotein E genotypes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900568-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0896-6273(03)00568-3
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
335924
OpenCitations bibliographic resource ID
335924
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
335924
PubMed ID
12971891
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12971891
retrieved
23 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
335924
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
