(Q36555889)

14 August 2017

A mechanism of paraquat toxicity involving nitric oxide synthase (English)

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14 August 2017

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B J Day

1

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14 August 2017

M Patel

2

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14 August 2017

L Calavetta

3

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14 August 2017

L Y Chang

4

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14 August 2017

J S Stamler

5

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14 August 2017

language of work or name

English

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publication date

1 October 1999

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14 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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14 August 2017

96

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14 August 2017

12760-12765

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14 August 2017

22

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Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Nitric oxide as a mediator of oxidant lung injury due to paraquat

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Neuronal NADPH diaphorase is a nitric oxide synthase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Nitric oxide as a secretory product of mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Nitric oxide, a novel neuronal messenger

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Nitric oxide regulation of superoxide-dependent lung injury: oxidant-protective actions of endogenously produced and exogenously administered nitric oxide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

NO wonder paraquat is toxic

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Young Scientists Award lecture 1981: The identification of an accumulation system for diamines and polyamines into the lung and its relevance to paraquat toxicity.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Ultrastructure of lung lesions produced by ingested chemicals. I. Effect of the herbicide paraquat on mouse lung

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Protection of Chinese hamster ovary cells from paraquat-mediated cytotoxicity by a low molecular weight mimic of superoxide dismutase (DF-Mn).

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Superoxide mediates the toxicity of paraquat for cultured mammalian cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Synergistic interactions between NADPH-cytochrome P-450 reductase, paraquat, and iron in the generation of active oxygen radicals

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Overproduction of human Mn-superoxide dismutase modulates paraquat-mediated toxicity in mammalian cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

NADH-dependent generation of reactive oxygen species by microsomes in the presence of iron and redox cycling agents

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Generation of superoxide by purified brain nitric oxide synthase

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Requirement for superoxide in excitotoxic cell death.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Nitric oxide mediates oxidant tissue injury caused by paraquat and xanthine oxidase

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Paraquat diaphorases in Escherichia coli.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Involvement of the reductase domain of neuronal nitric oxide synthase in superoxide anion production

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23088

Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide

21 October 2018

1 reference

12 December 2020

Purification of the inducible murine macrophage nitric oxide synthase. Identification as a flavoprotein

1 reference

12 December 2020

Antagonism by paraquat of the relaxing effects of acetylcholine and A23187 in rat thoracic aorta

1 reference

12 December 2020

Reduction of intrapulmonary shunt by low-dose inhaled nitric oxide in a patient with late-stage respiratory distress associated with paraquat poisoning

1 reference

12 December 2020

A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced lung injury in vivo

1 reference

12 December 2020

Lung epithelial cell-released nitric oxide protects against PMN-mediated cell injury

1 reference

12 December 2020

Superoxide anion formation from lucigenin: an electron spin resonance spin-trapping study

1 reference

12 December 2020

Mitochondrial NADH-quinone oxidoreductase of the outer membrane is responsible for paraquat cytotoxicity in rat livers

1 reference

12 December 2020

Nitric oxide inhalation for paraquat-induced lung injury

1 reference

12 December 2020

Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization

1 reference

12 December 2020

Inhaled nitric oxide in advanced paraquat intoxication

1 reference

12 December 2020

Differential paraquat uptake and redox kinetics of rat granular pneumocytes and alveolar macrophages

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12 December 2020

Potentiation of paraquat lethality in mice by bacterial lipopolysaccharide pretreatment

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12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.96.22.12760

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14 August 2017

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14 August 2017

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