(Q41634669)

5 October 2017

1 reference

title

Isoquinoline neurotoxins in the brain and Parkinson's disease (English)

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5 October 2017

Nagatsu T

1

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5 October 2017

publication date

1 October 1997

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5 October 2017

published in

Neuroscience Research

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5 October 2017

volume

29

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5 October 2017

issue

2

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5 October 2017

page(s)

99-111

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Selective 7-0-methylation of salsolinol in rat brain and heart in vivo

5 October 2017

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7 January 2021

Assay for the (R)- and (S)-enantiomers of salsolinols in biological samples and foods with ion-pair high-performance liquid chromatography using beta-cyclodextrin as a chiral mobile phase additive.

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7 January 2021

Enantiomeric composition of urinary salsolinol in parkinsonian patients after Madopar

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7 January 2021

Gas chromatographic/mass spectrometric methodology for simultaneous assay of salsolinol, dopamine, norepinephrine, dihydroxyphenylacetic acid and dihydroxyphenylethanol

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7 January 2021

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Inhibition of tyrosine hydroxylation in tissue slices of the rat striatum by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

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Early and late effects of systemically administered 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on tyrosine hydroxylase activity in vitro and on tyrosine hydroxylation in tissue slices of mouse striatum

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7 January 2021

The effects of pyridinium salts, structurally related compounds of 1-methyl-4-phenylpyridinium ion (MPP+), on tyrosine hydroxylation in rat striatal tissue slices

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7 January 2021

High-performance liquid chromatographic determination of 1,2,3,4-tetrahydroisoquinoline in rat brain with fluorescence detection

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7 January 2021

Presence of N-methyldopamine in parkinsonian and normal human brains

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7 January 2021

Endogenous synthesis of N-methylnorsalsolinol in rat brain during in vivo microdialysis with epinine

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7 January 2021

Detection of 1-phenyl-N-methyl-1,2,3,4-tetrahydroisoquinoline and 1-phenyl-1,2,3,4-tetrahydroisoquinoline in human brain by gas chromatography—tandem mass spectrometry

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7 January 2021

Effect of the 1-methyl-4-phenylpyridinium ion on phosphorylation of tyrosine hydroxylase in rat pheochromocytoma PC12h cells.

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7 January 2021

Tetrahydroisoquinoline and 1-methyl-tetrahydroisoquinoline as novel endogenous amines in rat brain

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7 January 2021

1‐Benzyl‐1,2,3,4‐Tetrahydroisoquinoline as a Parkinsonism‐Inducing Agent: A Novel Endogenous Amine in Mouse Brain and Parkinsonian CSF

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7 January 2021

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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7 January 2021

Accumulation of a Tetrahydroisoquinoline in Phenylketonuria

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7 January 2021

1,2,3,4-Tetrahydro-2-methyl-4,6,7-isoquinolinetriol inhibits tyrosine hydroxylase activity in rat striatal synaptosomes

1 reference

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7 January 2021

Presence of tetrahydroisoquinoline and 1-methyl-tetrahydro-isoquinoline in foods: Compounds related to Parkinson's disease

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7 January 2021

Confirmation of the enantiomers of 1-methyl-1,2,3,4-tetrahydroisoquinoline in the mouse brain and foods applying gas chromatography/mass spectrometry with negative ion chemical ionization

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

N-methylation of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (R)-salsolinol, in rat brains: in vivo microdialysis study.

1 reference

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7 January 2021

N-methyl(r)salsolinol produces hydroxyl radicals: Involvement to neurotoxicity

1 reference

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7 January 2021

A dopaminergic neurotoxin, (R)-N-methylsalsolinol, increases in parkinsonian cerebrospinal fluid

1 reference

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7 January 2021

A systematic regional study of brain salsolinol levels during and immediately following chronic ethanol ingestion in rats

1 reference

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7 January 2021

Inhibition of tyrosine hydroxylase by R and S enantiomers of salsolinol, 1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Inhibition of type A and B monoamine oxidase by 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines and their N-methylated derivatives

1 reference

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7 January 2021

Effects of repeated systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal tyrosine hydroxylase activity in vitro and tyrosine hydroxylase content

1 reference

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7 January 2021

Presence of methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines, derivatives of the neurotoxin isoquinoline, in parkinsonian lumbar CSF.

1 reference

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7 January 2021

Gas chromatographic-mass spectrometric screening procedure for the identification of formaldehyde-derived tetrahydroisoquinolines in human urine

1 reference

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7 January 2021

Alcohol Drinking: Abnormal Intake Caused by Tetrahydropapaveroline in Brain

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7 January 2021

Inhibition of the tyrosine hydroxylase system by MPTP, 1-methyl-4-phenylpyridinium ion (MPP+) and the structurally related compounds in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

An endogenous substance of the brain, tetrahydroisoquinoline, produces parkinsonism in primates with decreased dopamine, tyrosine hydroxylase and biopterin in the nigrostriatal regions

1 reference

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7 January 2021

Inhibition of monoamine oxidase by N-methylisoquinolinium ion

1 reference

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7 January 2021

Inhibition of type A monoamine oxidase by methylquinolines and structurally related compounds

1 reference

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7 January 2021

A N-methyltransferase in human brain catalyses N-methylation of 1,2,3,4-tetrahydroisoquinoline into N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of a dopaminergic neurotoxin, N-methylisoquinolinium ion

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Oxidation of N-methyl-1,2,3,4-tetrahydroisoquinoline into the N-methyl-isoquinolinium ion by monoamine oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Binding of 1,2(N)-dimethyl-6,7-dihydroxy-isoquinolinium ion to melanin: effects of ferrous and ferric ion on the binding

1 reference

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7 January 2021

Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

A novel enzyme enantio-selectively synthesizes (R)salsolinol, a precursor of a dopaminergic neurotoxin, N-methyl(R)salsolinol.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Catecholamine receptors and cyclic and formation in the central nervous system: Effects of tetrahydroisoquinoline derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Presence of tetrahydroisoquinoline and 2-methyl-tetrahydroquinoline in parkinsonian and normal human brains

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Migration of tetrahydroisoquinoline, a possible parkinsonian neurotoxin, into monkey brain from blood as proved by gas chromatography-mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Detection of tetrahydroisoquinoline in parkinsonian brain as an endogenous amine by use of gas chromatography-mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Presence of tetrahydroisoquinoline, a parkinsonism-related compound, in foods

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Presence of 2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline and 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, novel endogenous amines, in parkinsonian and normal human brains.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Endogenous synthesis of N-methylsalsolinol, an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, in rat brain during in vivo microdialysis with salsolinol, as demonstrated by gas chromatography-mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Metabolism and brain accumulation of tetrahydroisoquinoline (TIQ) a possible parkinsonism inducing substance, in an animal model of a poor debrisoquine metabolizer

1 reference

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7 January 2021

Confirmation of an unexpected brain O-methylation pattern for the dopamine-derived tetrahydroisoquinoline, salsolinol

1 reference

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7 January 2021

Determination of tetrahydroisoquinoline alkaloids in biological materials with high performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Effect of long-term administration of 1,2,3,4-tetrahydroisoquinoline (TIQ) on striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) content in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Tetrahydroisoquinoline alkaloids: in vivo metabolites of L-dopa in man.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Analysis of salsolinol in human brain using high-performance liquid chromatography with electrochemical detection

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Analysis of salsolinol and salsoline in biological samples using deuterium-labelled internal standards and gas chromatography--mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Increased salsolinol levels in rat striatum and limbic forebrain following chronic ethanol treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Identification and quantification of 1-carboxysalsolinol and salsolinol in biological samples by gas chromatography--mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Interaction of 1,2,3,4-Tetrahydroisoquinoline with Some Components of Cigarette Smoke: Potential Implications for Parkinson's Disease

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7 January 2021

Possible New Metabolites mediating Actions of L-Dopa

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Ratio of the R and S enantiomers of salsolinol in food and human urine

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Selective inhibition of complex I by N-methylisoquinolinium ion and N-methyl-1,2,3,4-tetrahydroisoquinoline in isolated mitochondria prepared from mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Cytotoxicity of endogenous isoquinolines to human dopaminergic neuroblastoma SH-SY5Y cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

1-Methyl-1,2,3,4-tetrahydroisoquinoline, decreasing in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mouse, prevents parkinsonism-like behavior abnormalities.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Tetrahydroisoquinolines derived from catecholamines or dopa: Effects on brain tyrosine hydroxylase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Neurotoxins: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, 1,2,3,4-tetrahydroisoquinoline and 1-methyl-6,7-dihydroxy-tetrahydroisoquinoline as substrates for FAD-containing monooxygenase of porcine liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Parkinsonism in monkeys produced by chronic administration of an endogenous substance of the brain, tetrahydroisoquinoline: the behavioral and biochemical changes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

Tetrahydroisoquinolines: a review

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https://api.crossref.org/works/10.1016%2FS0168-0102%2897%2900083-7

7 January 2021

10.1016/S0168-0102(97)00083-7

Identifiers

DOI

1 reference

5 October 2017

1 reference