(Q39401687)

11 September 2017

title

p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism (English)

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11 September 2017

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10

Mark P Mattson

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11 September 2017

Wenzhen Duan

1

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Xiaoxiang Zhu

2

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11 September 2017

Bruce Ladenheim

3

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11 September 2017

Qian-sheng Yu

4

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11 September 2017

Zhihong Guo

5

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Jon Oyler

6

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Roy G Cutler

7

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11 September 2017

Jean Lud Cadet

8

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Nigel H Greig

9

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11 September 2017

publication date

1 November 2002

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11 September 2017

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11 September 2017

volume

52

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11 September 2017

issue

5

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11 September 2017

page(s)

597-606

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

11 September 2017

cites work

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

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Alpha-synuclein and Parkinson's disease

21 January 2018

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Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

21 January 2018

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

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Selective loss of subpopulations of ventral mesencephalic dopaminergic neurons in the monkey following exposure to MPTP.

21 January 2018

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Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

21 January 2018

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Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors

21 January 2018

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Apoptosis in neurodegenerative disorders

21 January 2018

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Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

21 January 2018

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Role of p53 family members in apoptosis

21 January 2018

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Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease

21 January 2018

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p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PC12 cells.

21 January 2018

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The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury

21 January 2018

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Induction of tumor suppressor p53 and DNA fragmentation in organotypic hippocampal cultures following excitotoxin treatment

21 January 2018

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Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity

21 January 2018

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

21 January 2018

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A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

21 January 2018

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Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease

21 January 2018

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Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice

21 January 2018

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Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

21 January 2018

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An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease

21 January 2018

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Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

21 January 2018

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Regulation of the G2/M transition by p53.

21 January 2018

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The role of p53 in tumour suppression: lessons from mouse models

21 January 2018

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Induction of neuronal death by α-synuclein

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ANA.10350

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11 September 2017

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