(Q48379973)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9763461%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2 (English)

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5 December 2019

1 reference

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6

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5 December 2019

9

M F Beal

1 reference

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5 December 2019

author name string

L Yang

1

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5 December 2019

R T Matthews

2

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5 December 2019

J B Schulz

3

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5 December 2019

T Klockgether

4

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5 December 2019

A W Liao

5

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5 December 2019

J B Penney

7

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5 December 2019

B T Hyman

8

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5 December 2019

language of work or name

English

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publication date

1 October 1998

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5 December 2019

published in

Journal of Neuroscience

1 reference

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5 December 2019

volume

18

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5 December 2019

page(s)

8145-8152

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5 December 2019

issue

20

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Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

5 December 2019

cites work

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12 December 2020

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

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12 December 2020

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

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12 December 2020

Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds

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12 December 2020

Quantitative Autoradiography of [ 3 H]Muscimol Binding in Rat Brain

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12 December 2020

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

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12 December 2020

Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice.

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12 December 2020

Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity

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12 December 2020

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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12 December 2020

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

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12 December 2020

On the question of apoptosis in the parkinsonian substantia nigra

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12 December 2020

Bcl-2 promotes regeneration of severed axons in mammalian CNS

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12 December 2020

Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

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12 December 2020

Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement

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12 December 2020

Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest

1 reference

12 December 2020

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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12 December 2020

Inhibition of Bax channel-forming activity by Bcl-2

1 reference

12 December 2020

The MPTP model: versatile contributions to the treatment of idiopathic Parkinson's disease

1 reference

12 December 2020

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

1 reference

12 December 2020

Shift of the cellular oxidation-reduction potential in neural cells expressing Bcl-2.

1 reference

12 December 2020

Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease

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12 December 2020

Mitochondrial control of nuclear apoptosis.

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12 December 2020

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

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12 December 2020

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

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12 December 2020

Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux

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12 December 2020

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

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12 December 2020

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

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12 December 2020

Bcl-2 expression causes redistribution of glutathione to the nucleus

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12 December 2020

Changes in [3H]muscimol binding in substantia nigra, entopeduncular nucleus, globus pallidus, and thalamus after striatal lesions as demonstrated by quantitative receptor autoradiography

1 reference

12 December 2020

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

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12 December 2020

Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases

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12 December 2020

Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes

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12 December 2020

Movement disorder following excitotoxin lesions in primates

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12 December 2020

Bcl-2 targets the protein kinase Raf-1 to mitochondria

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12 December 2020

BCL-2 expression and mitochondrial activity in leukemic cells with different sensitivity to glucocorticoid-induced apoptosis.

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12 December 2020

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

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12 December 2020

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12 December 2020

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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12 December 2020

Channel formation by antiapoptotic protein Bcl-2.

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12 December 2020

bcl-2 protein is increased in the brain from parkinsonian patients

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12 December 2020

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.

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12 December 2020

Bcl-2 expression in neural cells blocks activation of ICE/CED-3 family proteases during apoptosis.

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12 December 2020

Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease.

1 reference

12 December 2020

Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells

1 reference

12 December 2020

Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons.

1 reference

12 December 2020

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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12 December 2020

Histochemical detection of apoptosis in Parkinson's disease.

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12 December 2020

[3H]mazindol binding associated with neuronal dopamine uptake sites in corpus striatum membranes.

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12 December 2020

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis

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12 December 2020

Expression of BCL-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity

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12 December 2020

Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis

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12 December 2020

Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production

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12 December 2020

Direct evidence for antioxidant effect of Bcl-2 in PC12 rat pheochromocytoma cells

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12 December 2020

A Bcl-2 antisense oligonucleotide increases alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) toxicity in cortical cultures.

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12 December 2020

Bcl-2 protects neural cells from cyanide/aglycemia-induced lipid oxidation, mitochondrial injury, and loss of viability

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12 December 2020

bcl-2 is expressed in neurons that survive focal ischemia in the rat.

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12 December 2020

Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo

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12 December 2020

Expression of bcl-2 inhibits necrotic neural cell death.

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12 December 2020

Homocysteic acid lesions in rat striatum spare somatostatin—;Neuropeptide Y (NADPH-diaphorase) neurons

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12 December 2020

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

1 reference

12 December 2020

10.1523/JNEUROSCI.18-20-08145.1998

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9763461%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

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5 December 2019

1 reference