(Q34142252)

31 July 2017

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title

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases (English)

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31 July 2017

1 reference

Sherman MY

1

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PubMed ID

11182078

31 July 2017

Goldberg AL

series ordinal

2

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PubMed ID

11182078

31 July 2017

language of work or name

English

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publication date

1 January 2001

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31 July 2017

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31 July 2017

29

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31 July 2017

15-32

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31 July 2017

1

1 reference

Abnormal proteins serve as eukaryotic stress signals and trigger the activation of heat shock genes

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Intracellular localization of proteasomal degradation of a viral antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

CAG expansion affects the expression of mutant Huntingtin in the Huntington's disease brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Denatured hemoglobin in sickle erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Evidence for a role of Hsp70 in the regulation of the heat shock response in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Transgenic mice in the study of polyglutamine repeat expansion diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

PAN, the proteasome-activating nucleotidase from archaebacteria, is a protein-unfolding molecular chaperone

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Degradation of alpha-synuclein by proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Ubiquitin-dependent degradation of certain protein substrates in vitro requires the molecular chaperone Hsc70

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

The base of the proteasome regulatory particle exhibits chaperone-like activity

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

The Hsp70 and Hsp60 chaperone machines

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Role of oxidants in ischemic brain damage

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Intracellular signaling from the endoplasmic reticulum to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Cellular adaptation in metal toxicology and metallothionein

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Free Radical and Oxidative Damage in Human Blood Cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

From Charcot to SOD1: mechanisms of selective motor neuron death in ALS.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

HLA-DR beta chains enter into an aggregated complex containing GRP-78/BiP prior to their degradation by the pre-Golgi degradative pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Structure and functions of the 20S and 26S proteasomes

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

A receptor for the selective uptake and degradation of proteins by lysosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Lysosomes, a meeting point of proteins, chaperones, and proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Progress in pathogenesis studies of spinocerebellar ataxia type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Size-dependent disaggregation of stable protein aggregates by the DnaK chaperone machinery.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Cellular and molecular mechanisms of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Activity and regulation of the centrosome-associated proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Identification of genes that modify ataxin-1-induced neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Mechanisms of kidney cell injury from metals

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

ICE, neuronal apoptosis and neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Principles of chaperone-assisted protein folding: differences between in vitro and in vivo mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

MEKK1/JNK signaling stabilizes and activates p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Induction of heat-shock protein synthesis and thermotolerance in EL-4 ascites tumor cells by transient ATP depletion after ischemic stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Role of Hsp70 in regulation of stress-kinase JNK: implications in apoptosis and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Production of abnormal proteins in E. coli stimulates transcription of lon and other heat shock genes

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Protein aggregation and inclusion body formation in Escherichia coli rpoH mutant defective in heat shock protein induction.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Degradation of oxidized proteins in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Huntingtin: a single bait hooks many species

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Roles of molecular chaperones in protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

1 reference

7 January 2021

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

1 reference

7 January 2021

Dual roles of proteasome in the metabolism of presenilin 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Protein folding in vivo: unraveling complex pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Aggresomes: a cellular response to misfolded proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Peptides containing glutamine repeats as substrates for transglutaminase-catalyzed cross-linking: relevance to diseases of the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Thermal protein denaturation and protein aggregation in cells made thermotolerant by various chemicals: role of heat shock proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Skein-like inclusions in the neostriatum from a case of amyotrophic lateral sclerosis with dementia.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Genetic suppression of polyglutamine toxicity in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Caspase-3 cleaves the expanded androgen receptor protein of spinal and bulbar muscular atrophy in a polyglutamine repeat length-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Biosynthesis and degradation of CFTR.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Molecular cloning and functional expression of a human peptide methionine sulfoxide reductase (hMsrA)

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Proteasome inhibitors cause induction of heat shock proteins and trehalose, which together confer thermotolerance in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Involvement of the molecular chaperone Ydj1 in the ubiquitin-dependent degradation of short-lived and abnormal proteins in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

The ubiquitin pathway in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Induction of thermotolerance and enhanced heat shock protein synthesis in Chinese hamster fibroblasts by sodium arsenite and by ethanol

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

The DnaK chaperone modulates the heat shock response of Escherichia coli by binding to the sigma 32 transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Expression of polyglutamine-expanded Huntingtin activates the SEK1-JNK pathway and induces apoptosis in a hippocampal neuronal cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Diminished heat shock response in the aged myocardium

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Endosome-lysosomes, ubiquitin and neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Alpha synuclein in neurodegenerative disorders: murderer or accomplice?

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Expression of extended polyglutamine sequentially activates initiator and effector caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Chromosomal localization of the mammalian peptide-methionine sulfoxide reductase gene and its differential expression in various tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Overexpression of peptide-methionine sulfoxide reductase in Saccharomyces cerevisiae and human T cells provides them with high resistance to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Induced thermotolerance to apoptosis in a human T lymphocyte cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Antagonistic interactions between yeast chaperones Hsp104 and Hsp70 in prion curing

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Modulation of intracellular protein degradation by SSB1-SIS1 chaperon system in yeast S. cerevisiae.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

The maintenance of the accuracy of protein synthesis and its relevance to ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Protein disaggregation mediated by heat-shock protein Hsp104.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Support for the prion hypothesis for inheritance of a phenotypic trait in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Glutamine repeats and neurodegenerative diseases: molecular aspects

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Altered cellular responsiveness during ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Overexpression of bacterial hemoglobin causes incorporation of pre-beta-lactamase into cytoplasmic inclusion bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Negative regulation of the Apaf-1 apoptosome by Hsp70

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Heat shock proteins: regulators of stress response and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

The ubiquitin-proteasome pathway and pathogenesis of human diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Molecular chaperones as HSF1-specific transcriptional repressors

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Advanced glycation endproducts are deposited in neuronal hyaline inclusions: a study on familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Genetic analysis of ubiquitin-dependent protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Recognition of misfolding proteins by PA700, the regulatory subcomplex of the 26 S proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Puromycin induces apoptosis of developing chick sympathetic neurons in a similar manner to NGF-deprivation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Ca2+-free calmodulin and calmodulin damaged by in vitro aging are selectively degraded by 26 S proteasomes without ubiquitination.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Scrapie prions selectively modify the stress response in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and sperm.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Maintenance and inheritance of yeast prions.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Heat shock causes protein aggregation and reduced protein solubility at the centrosome and other cytoplasmic locations

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Caspase activation during apoptotic cell death induced by expanded polyglutamine in N2a cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

UBI4, the polyubiquitin gene of Saccharomyces cerevisiae, is a heat shock gene that is also subject to catabolite derepression control

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Toward understanding the molecular pathology of Huntington's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Dynamic association of proteasomal machinery with the centrosome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Evidence that endoplasmic reticulum (ER)-associated degradation of cystic fibrosis transmembrane conductance regulator is linked to retrograde translocation from the ER membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

The function of HSP72 in suppression of c-Jun N-terminal kinase activation can be dissociated from its role in prevention of protein damage

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Triggering of neuronal cell death by accumulation of activated SEK1 on nuclear polyglutamine aggregations in PML bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900177-5

7 January 2021

10.1016/S0896-6273(01)00177-5

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11182078