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(Q29812582)
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COP9 signalosome subunit 4 Dmel_CG8725
Protein found in Drosophila melanogaster
COP9 complex homolog subunit 4
CSN4
CG8725-PB
CG8725-PA
COP9 signalosome subunit 4
CG8725 gene product from transcript CG8725-RA
CSN4-PA
CSN4-PB
drosophila COP9 signalosome homolog 4
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V345
part of
Winged helix DNA-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V345
Winged helix-like DNA-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V345
COP9 signalosome complex subunit 4
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V345
Proteasome component (PCI) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V345
encoded by
CSN4
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V345
molecular function
protein binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
Protein competition switches the function of COP9 from self-renewal to differentiation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IPI
retrieved
8 April 2019
stated in
The COP9 signalosome is essential for development of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IPI
NEDD8-specific protease activity
determination method
IDA
1 reference
retrieved
27 March 2018
stated in
The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V345&geneProductId=UniProtKB:Q9V345
determination method
IDA
NEDD8-specific protease activity
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IBA
cell component
nucleus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V345
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IEA
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V345
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IEA
cytosol
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IBA
COP9 signalosome
determination method
IEA
IPI
NAS
TAS
5 references
retrieved
27 March 2018
stated in
Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V345&geneProductId=UniProtKB:Q9V345
determination method
TAS
retrieved
27 March 2018
stated in
The COP9 Signalosome
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V345&geneProductId=UniProtKB:Q9V345
determination method
NAS
retrieved
27 March 2018
stated in
The COP9 signalosome is essential for development of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V345&geneProductId=UniProtKB:Q9V345
determination method
IPI
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V345
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V345&geneProductId=UniProtKB:Q9V345
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V345&geneProductId=UniProtKB:Q9V345
determination method
IEA
COP9 signalosome
determination method
IBA
IEA
IPI
NAS
TAS
6 references
retrieved
8 April 2019
stated in
Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
TAS
retrieved
8 April 2019
stated in
The COP9 Signalosome
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
NAS
retrieved
8 April 2019
stated in
The COP9 signalosome is essential for development of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IPI
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V345
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IBA
biological process
protein deneddylation
determination method
IMP
2 references
retrieved
8 April 2019
stated in
The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis
GOA
curator
UniProt
UniProt protein ID
Q9V345
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IMP
retrieved
8 April 2019
stated in
The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IMP
compound eye photoreceptor cell differentiation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IMP
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V345
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IEA
germ cell development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
CSN maintains the germline cellular microenvironment and controls the level of stem cell genes via distinct CRLs in testes of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IMP
cell differentiation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V345
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IEA
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Retinoblastoma protein regulation by the COP9 signalosome.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IMP
female germ-line stem cell population maintenance
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Protein competition switches the function of COP9 from self-renewal to differentiation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IMP
male germ-line cyst encapsulation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
CSN maintains the germline cellular microenvironment and controls the level of stem cell genes via distinct CRLs in testes of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IMP
oogenesis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9V345
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IEA
protein stabilization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Retinoblastoma protein regulation by the COP9 signalosome.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V345
determination method
IMP
has part(s)
Proteasome component (PCI) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9V345
Identifiers
RefSeq protein ID
NP_001163080
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
35759
NP_477444
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
35759
UniProt protein ID
Q9V345
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9V345
Ensembl protein ID
FBpp0087935
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0087935
FBpp0290448
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0290448
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