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(Q29814362)
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English
Arrow Dmel_CG5912
Protein found in Drosophila melanogaster
arrow
LRP5/6/Arrow
Dm arrow
arr
CG5912-PA
LDL-related protein 6
arr-PA
LDLR-like
CG5912 gene product from transcript CG5912-RA
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A1Z9D7
part of
Low density lipoprotein receptor-related protein 5/6
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A1Z9D7
LDL receptor-like superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A1Z9D7
Six-bladed beta-propeller, TolB-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A1Z9D7
EGF-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Low-density lipoprotein (LDL) receptor class A, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
Low-density lipoprotein (LDL) receptor class A repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
LDLR class B repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A1Z9D7
encoded by
arr
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A1Z9D7
molecular function
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Wnt pathway activation by ADP-ribosylation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IPI
coreceptor activity
determination method
IGI
1 reference
retrieved
8 April 2019
stated in
Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IGI
Wnt-protein binding
determination method
IEA
IPI
3 references
retrieved
16 July 2018
stated in
Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IPI
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
A1Z9D7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IEA
Wnt-activated receptor activity
determination method
IDA
IEA
2 references
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IEA
retrieved
16 July 2018
stated in
Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IDA
coreceptor activity involved in Wnt signaling pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A1Z9D7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IEA
Wnt-protein binding
determination method
IBA
IEA
IPI
4 references
retrieved
8 April 2019
stated in
Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IPI
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A1Z9D7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IBA
Wnt-activated receptor activity
determination method
IBA
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IEA
retrieved
8 April 2019
stated in
Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IBA
cell component
early endosome
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IDA
late endosome
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IDA
plasma membrane
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A1Z9D7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IEA
retrieved
8 April 2019
stated in
Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A1Z9D7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IEA
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A1Z9D7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IEA
biological process
compound eye morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Patterning the peripheral retina of the fly: decoding a gradient
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A1Z9D7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IEA
segment polarity determination
determination method
IMP
2 references
retrieved
8 April 2019
stated in
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
retrieved
8 April 2019
stated in
Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
nervous system development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
RNA interference screen to identify genes required for Drosophila embryonic nervous system development.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
long-term memory
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Wnt signaling is required for long-term memory formation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
imaginal disc-derived wing margin morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
Wnt signaling pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A1Z9D7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IEA
leg disc pattern formation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
regulation of compound eye pigmentation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Organization of the peripheral fly eye: the roles of Snail family transcription factors in peripheral retinal apoptosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
canonical Wnt signaling pathway
determination method
IEA
IGI
IMP
7 references
retrieved
16 July 2018
stated in
Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IMP
retrieved
16 July 2018
stated in
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IMP
retrieved
16 July 2018
stated in
The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IMP
retrieved
16 July 2018
stated in
Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IGI
retrieved
16 July 2018
stated in
Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IGI
retrieved
16 July 2018
stated in
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IGI
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9D7&geneProductId=UniProtKB:A1Z9D7
determination method
IEA
cell elongation involved in imaginal disc-derived wing morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Wingless signaling and the control of cell shape in Drosophila wing imaginal discs
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
canonical Wnt signaling pathway
determination method
IBA
IEA
IGI
IMP
8 references
retrieved
8 April 2019
stated in
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
retrieved
8 April 2019
stated in
The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
retrieved
8 April 2019
stated in
Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IMP
retrieved
8 April 2019
stated in
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IGI
retrieved
8 April 2019
stated in
Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IGI
retrieved
8 April 2019
stated in
Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IGI
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9D7
determination method
IBA
has part(s)
Low-density lipoprotein (LDL) receptor class A, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A1Z9D7
EGF-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A1Z9D7
LDLR class B repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A1Z9D7
low-density lipoprotein (LDL) receptor class A repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A1Z9D7
Identifiers
RefSeq protein ID
NP_524737
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
44279
UniProt protein ID
A1Z9D7
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A1Z9D7
Ensembl protein ID
FBpp0086821
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0086821
Sitelinks
Wikipedia
(0 entries)
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Wikibooks
(0 entries)
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Wikinews
(0 entries)
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Wikiquote
(0 entries)
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
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Wiktionary
(0 entries)
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Multilingual sites
(0 entries)
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