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(Q29815983)
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Septin interacting protein 3 Dmel_CG1937
Protein found in Drosophila melanogaster
CG1937 gene product from transcript CG1937-RB
CG1937-PB
septin interacting protein 3
septin-interacting protein 3
synoviolin
sip3-PA
sip3-PB
sip3
CG1937-PA
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q95SP2
part of
E3 ubiquitin-protein ligase synoviolin/Hrd1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q95SP2
Zinc finger, RING/FYVE/PHD-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q95SP2
Zinc finger, RING-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q95SP2
encoded by
sip3
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q95SP2
molecular function
p53 binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IPI
ubiquitin-protein transferase activity
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
ISS
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'
GOA
curator
UniProt
UniProt protein ID
Q95SP2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IPI
zinc ion binding
determination method
ISM
1 reference
retrieved
8 April 2019
stated in
Comprehensively surveying structure and function of RING domains from Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
ISM
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q95SP2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q95SP2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
unfolded protein binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IBA
ubiquitin protein ligase activity
determination method
IDA
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q95SP2&geneProductId=UniProtKB:Q95SP2
determination method
IEA
retrieved
27 March 2018
stated in
Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q95SP2&geneProductId=UniProtKB:Q95SP2
determination method
IDA
ubiquitin-specific protease binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IBA
ubiquitin protein ligase activity
determination method
IBA
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
retrieved
8 April 2019
stated in
Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IBA
cell component
Hrd1p ubiquitin ligase complex
determination method
IBA
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q95SP2&geneProductId=UniProtKB:Q95SP2
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q95SP2&geneProductId=UniProtKB:Q95SP2
determination method
IBA
endoplasmic reticulum
determination method
IEA
ISS
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q95SP2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q95SP2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
endoplasmic reticulum membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q95SP2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q95SP2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
integral component of membrane
determination method
IEA
ISM
2 references
retrieved
8 April 2019
stated in
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
ISM
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q95SP2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
Derlin-1 retrotranslocation complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IBA
endoplasmic reticulum quality control compartment
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q95SP2&geneProductId=UniProtKB:Q95SP2
determination method
IBA
Hrd1p ubiquitin ligase complex
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
biological process
protein polyubiquitination
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q95SP2&geneProductId=UniProtKB:Q95SP2
determination method
IBA
protein ubiquitination
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q95SP2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
retrieved
8 April 2019
stated in
Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IDA
ubiquitin-dependent ERAD pathway
determination method
IBA
IEA
ISS
4 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q95SP2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
ISS
retrieved
8 April 2019
stated in
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IBA
endoplasmic reticulum unfolded protein response
determination method
IGI
1 reference
retrieved
27 March 2018
stated in
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q95SP2&geneProductId=UniProtKB:Q95SP2
determination method
IGI
response to endoplasmic reticulum stress
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IMP
intestinal stem cell homeostasis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IMP
regulation of translation in response to endoplasmic reticulum stress
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IMP
ubiquitin-dependent protein catabolic process
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IBA
endoplasmic reticulum unfolded protein response
determination method
IBA
IGI
2 references
retrieved
8 April 2019
stated in
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IGI
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IBA
retrograde protein transport, ER to cytosol
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IBA
protein K48-linked ubiquitination
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q95SP2
determination method
IBA
has part(s)
Zinc finger, RING-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q95SP2
Identifiers
RefSeq protein ID
NP_001263152
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
43747
NP_651894
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
43747
UniProt protein ID
Q95SP2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q95SP2
Ensembl protein ID
FBpp0085201
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0085201
FBpp0303146
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0303146
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