(Q29819298)

Metallopeptidase, catalytic domain superfamily

1 reference

Peptidase M10A

1 reference

PGBD-like superfamily

1 reference

Peptidase M10A, catalytic domain, protein family

1 reference

Hemopexin-like domain, protein family

1 reference

Peptidase, metallopeptidase family

1 reference

Peptidase M10, metallopeptidase family

1 reference

Peptidoglycan binding-like, protein family

1 reference

Hemopexin-like repeats, protein family

1 reference

A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

endopeptidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

metalloendopeptidase activity

IEA

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

8 April 2019

Structural and enzymatic characterization of Drosophila Dm2-MMP, a membrane-bound matrix metalloproteinase with tissue-specific expression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

external side of plasma membrane

cell component

1 reference

8 April 2019

A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

integral component of membrane

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

activation of innate immune response

biological process

1 reference

8 April 2019

Cleavage of PGRP-LC receptor in the Drosophila IMD pathway in response to live bacterial infection in S2 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

embryonic heart tube formation

IDA

1 reference

8 April 2019

Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

cardioblast migration to the midline involved in heart rudiment formation

1 reference

8 April 2019

Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

2 references

substrate-dependent cell migration

1 reference

8 April 2019

Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

Glia ECM interactions are required to shape the Drosophila nervous system.

ventral cord development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

open tracheal system development

1 reference

8 April 2019

Spatial restriction of FGF signaling by a matrix metalloprotease controls branching morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

tracheal outgrowth, open tracheal system

1 reference

8 April 2019

Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

adult fat body development

1 reference

8 April 2019

Mmp1 and Mmp2 cooperatively induce Drosophila fat body cell dissociation with distinct roles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion.

imaginal disc eversion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

motor neuron axon guidance

1 reference

8 April 2019

Matrix metalloproteinases promote motor axon fasciculation in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

Active JNK-dependent secretion of Drosophila Tyrosyl-tRNA synthetase by loser cells recruits haemocytes during cell competition.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

Matrix metalloproteinase 2 is required for ovulation and corpus luteum formation in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

basement membrane disassembly

1 reference

8 April 2019

Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

tracheal pit formation in open tracheal system

1 reference

8 April 2019

Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

negative regulation of fibroblast growth factor receptor signaling pathway

1 reference

8 April 2019

Spatial restriction of FGF signaling by a matrix metalloprotease controls branching morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

A secreted MMP is required for reepithelialization during wound healing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

cell-cell junction organization

1 reference

8 April 2019

Mmp1 and Mmp2 cooperatively induce Drosophila fat body cell dissociation with distinct roles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

1 reference

8 April 2019

Spatial restriction of FGF signaling by a matrix metalloprotease controls branching morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

imaginal disc fusion, thorax closure

1 reference

8 April 2019

JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

basement membrane organization

1 reference

8 April 2019

Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

negative regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

fasciculation of motor neuron axon

IGI

1 reference

8 April 2019

Matrix metalloproteinases promote motor axon fasciculation in the Drosophila embryo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

negative regulation of extracellular matrix assembly

1 reference

8 April 2019

Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

negative regulation of stem cell proliferation

1 reference

8 April 2019

A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

extracellular matrix organization

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

collagen catabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

Peptidase M10A, catalytic domain

has part(s)

1 reference

Peptidase, metallopeptidase

1 reference

Hemopexin-like domain

1 reference

Peptidase M10, metallopeptidase

1 reference

Hemopexin-like repeats

1 reference

Peptidoglycan binding-like

1 reference