(Q29819518)

Moesin tail domain superfamily

1 reference

FERM/acyl-CoA-binding protein superfamily

1 reference

PH-like domain superfamily

1 reference

FERM superfamily, second domain

1 reference

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

8.A.25.1.3

retrieved

2 October 2019

hierarchical database ID heuristic

Band 4.1 domain, protein family

1 reference

FERM central domain, protein family

1 reference

FERM, C-terminal PH-like domain, protein family

1 reference

FERM, N-terminal domain, protein family

1 reference

FERM domain, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

5 references

8 April 2019

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

alpha-spectrin is required for germline cell division and differentiation in the Drosophila ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Structural analysis of Drosophila merlin reveals functional domains important for growth control and subcellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

2 references

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

1 reference

27 February 2018

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24564&geneProductId=UniProtKB:Q24564

1 reference

8 April 2019

alpha-spectrin is required for germline cell division and differentiation in the Drosophila ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

1 reference

8 April 2019

Kibra and Merlin Activate the Hippo Pathway Spatially Distinct from and Independent of Expanded.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

1 reference

8 April 2019

Kibra and Merlin Activate the Hippo Pathway Spatially Distinct from and Independent of Expanded.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

cytoplasmic side of apical plasma membrane

1 reference

8 April 2019

Kibra is a regulator of the Salvador/Warts/Hippo signaling network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

regulation of cell growth

biological process

2 references

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

compound eye morphogenesis

IEP

1 reference

8 April 2019

The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

compound eye photoreceptor cell differentiation

1 reference

8 April 2019

The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

positive regulation of protein phosphorylation

1 reference

8 April 2019

Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24564&geneProductId=UniProtKB:Q24564

regulation of transcription, DNA-templated

IEA

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24564&geneProductId=UniProtKB:Q24564

3 references

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

IEA

male meiosis cytokinesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

2 references

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

sperm individualization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

negative regulation of cell population proliferation

6 references

8 April 2019

The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

1 reference

8 April 2019

Merlin, the Drosophila homologue of neurofibromatosis-2, is specifically required in posterior follicle cells for axis formation in the oocyte

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

regulation of signal transduction

1 reference

8 April 2019

The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

pole plasm mRNA localization

1 reference

8 April 2019

mRNA localization and ER-based protein sorting mechanisms dictate the use of transitional endoplasmic reticulum-golgi units involved in gurken transport in Drosophila oocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

1 reference

8 April 2019

The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

regulation of hippo signaling

1 reference

27 February 2018

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24564&geneProductId=UniProtKB:Q24564

regulation of cell population proliferation

1 reference

8 April 2019

Structural analysis of Drosophila merlin reveals functional domains important for growth control and subcellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

positive regulation of phosphorylation

1 reference

27 February 2018

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24564&geneProductId=UniProtKB:Q24564

regulation of apoptotic process

1 reference

27 February 2018

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24564&geneProductId=UniProtKB:Q24564

regulation of cell differentiation

1 reference

8 April 2019

The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

regulation of compound eye retinal cell programmed cell death

1 reference

8 April 2019

The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

meiotic chromosome separation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

negative regulation of glial cell proliferation

1 reference

8 April 2019

Regulation of Drosophila glial cell proliferation by Merlin-Hippo signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

protein localization to plasma membrane

1 reference

8 April 2019

Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

positive regulation of hippo signaling

6 references

8 April 2019

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

The WW domain protein Kibra acts upstream of Hippo in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

In vivo regulation of Yorkie phosphorylation and localization.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

8 April 2019

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

positive regulation of apoptotic process

1 reference

8 April 2019

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564

FERM, C-terminal PH-like domain

has part(s)

1 reference

FERM central domain

1 reference

Band 4.1 domain

1 reference

FERM domain

1 reference

FERM, N-terminal

1 reference

Transporter Classification Database ID

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

8.A.25.1.3

2 references

Transporter Classification database

retrieved

13 March 2020