(Q29819624)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

ubiquitin conjugating enzyme binding

IEA

1 reference

27 February 2018

Drosophila melanogaster Parkin ubiquitinates peanut and septin1 as an E3 ubiquitin-protein ligase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

ubiquitin protein ligase activity

IEA

1 reference

27 February 2018

Drosophila melanogaster Parkin ubiquitinates peanut and septin1 as an E3 ubiquitin-protein ligase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7

protein homodimerization activity

1 reference

8 April 2019

Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

3 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7

27 February 2018

PINK1 controls mitochondrial localization of Parkin through direct phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7

27 February 2018

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7

3 references

8 April 2019

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

Diminution of eIF4E activity suppresses parkin mutant phenotypes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

PINK1 controls mitochondrial localization of Parkin through direct phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

endoplasmic reticulum

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

protein polyubiquitination

biological process

1 reference

27 February 2018

Drosophila melanogaster Parkin ubiquitinates peanut and septin1 as an E3 ubiquitin-protein ligase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7

The PINK1/Parkin pathway regulates mitochondrial morphology

mitochondrial fission

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

mitochondrion organization

IGI

8 references

8 April 2019

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

The PINK1/Parkin pathway regulates mitochondrial morphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

The Drosophila parkin homologue is required for normal mitochondrial dynamics during spermiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

larval locomotory behavior

1 reference

8 April 2019

Optimization of wrMTrck to monitor Drosophila larval locomotor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

negative regulation of mitochondrial fusion

1 reference

8 April 2019

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

regulation of mitochondrion organization

1 reference

27 February 2018

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin

protein ubiquitination

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

Drosophila melanogaster Parkin ubiquitinates peanut and septin1 as an E3 ubiquitin-protein ligase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

sperm mitochondrion organization

1 reference

8 April 2019

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

positive regulation of compound eye pigmentation

1 reference

8 April 2019

Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

protein autoubiquitination

1 reference

8 April 2019

Drosophila melanogaster Parkin ubiquitinates peanut and septin1 as an E3 ubiquitin-protein ligase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

1 reference

8 April 2019

Zinc supplement greatly improves the condition of parkin mutant Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

neuron cellular homeostasis

1 reference

8 April 2019

Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

positive regulation of mitochondrial fission

1 reference

8 April 2019

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

regulation of cellular response to oxidative stress

1 reference

27 February 2018

Extended lifespan of Drosophila parkin mutants through sequestration of redox-active metals and enhancement of anti-oxidative pathways

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7

ubiquitin-dependent protein catabolic process

1 reference

27 February 2018

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7

autophagy of mitochondrion

3 references

8 April 2019

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

Mitochondrial contagion induced by Parkin deficiency in Drosophila hearts and its containment by suppressing mitofusin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

negative regulation of protein phosphorylation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

regulation of apoptotic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

positive regulation of locomotor rhythm

1 reference

8 April 2019

Drosophila PINK1 and parkin loss-of-function mutants display a range of non-motor Parkinson's disease phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

positive regulation of neuronal action potential

1 reference

8 April 2019

Drosophila PINK1 and parkin loss-of-function mutants display a range of non-motor Parkinson's disease phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

protein monoubiquitination

1 reference

8 April 2019

Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7KTX7

IBR domain

1 reference

stated in

InterPro Release 71.0