Wikidata

(Q29820703)

English

Epidermal growth factor receptor Dmel_CG10079

Protein found in Drosophila melanogaster

  • ellipse
  • faint little ball
  • torpedo
  • Egfr
  • torpedo/DER
  • Egfr-PA
  • Egfr-PB
  • drosophila epidermal growth factor receptor homologue
  • CG10079 gene product from transcript CG10079-RA
  • CG10079-PA
  • drosophila epidermal growth factor receptor
  • epidermal growth factor receptor
  • ellipse torpedo
  • morphological defects 1
  • EGF-receptor
  • dEGFR
  • CG10079-PB
  • DER-Ellipse
  • Egf receptor
In more languages

Statements

part of
molecular function
protein binding
determination method
IPI
6 references
retrieved
8 April 2019
stated in
An extracellular interactome of immunoglobulin and LRR proteins reveals receptor-ligand networks.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IPI
retrieved
8 April 2019
stated in
Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IPI
retrieved
8 April 2019
stated in
D-Cbl binding to Drk leads to dose-dependent down-regulation of EGFR signaling and increases receptor-ligand endocytosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IPI
retrieved
8 April 2019
stated in
Echinoid is essential for regulation of Egfr signaling and R8 formation during Drosophila eye development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IPI
retrieved
8 April 2019
stated in
Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IPI
retrieved
8 April 2019
stated in
Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IPI
cell component
biological process
epidermal growth factor receptor signaling pathway
determination method
IDA
IGI
IMP
13 references
retrieved
8 April 2019
stated in
Role of the EGFR/Ras/Raf pathway in specification of photoreceptor cells in the Drosophila retina.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IMP
retrieved
8 April 2019
stated in
MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IMP
retrieved
8 April 2019
stated in
Sprouty, an intracellular inhibitor of Ras signaling.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IMP
retrieved
8 April 2019
stated in
Dissecting the roles of the Drosophila EGF receptor in eye development and MAP kinase activation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IMP
retrieved
8 April 2019
stated in
Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IMP
retrieved
8 April 2019
stated in
Differential activity of Ras1 during patterning of the Drosophila dorsoventral axis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IGI
retrieved
8 April 2019
stated in
The sevenless signalling cassette mediates Drosophila EGF receptor function during epidermal development.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IGI
retrieved
8 April 2019
stated in
EGF domain swap converts a drosophila EGF receptor activator into an inhibitor
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IDA
retrieved
8 April 2019
stated in
Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IDA
retrieved
8 April 2019
stated in
Argos transcription is induced by the Drosophila EGF receptor pathway to form an inhibitory feedback loop.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IDA
retrieved
8 April 2019
stated in
Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog Spitz
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IDA
retrieved
8 April 2019
stated in
Inhibition of Drosophila EGF receptor activation by the secreted protein Argos.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IDA
retrieved
8 April 2019
stated in
The interaction between the Drosophila secreted protein argos and the epidermal growth factor receptor inhibits dimerization of the receptor and binding of secreted spitz to the receptor
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412
determination method
IDA

Identifiers

 
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