(Q34126334)

31 July 2017

MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila (English)

1 reference

Phosphatidylinositol 3-kinase 92E Dmel_CG4141

31 July 2017

0 references

1 reference

Insulin-like receptor Dmel_CG18402

1 reference

Kinase suppressor of ras Dmel_CG2899

1 reference

Epidermal growth factor receptor Dmel_CG10079

1 reference

Raf oncogene Dmel_CG2845

1 reference

Akt1 Dmel_CG4006

1 reference

Forkhead box, sub-group O Dmel_CG3143

1 reference

Downstream of raf1 Dmel_CG15793

1 reference

Pointed Dmel_CG17077

1 reference

Ribosomal protein S6 kinase Dmel_CG10539

1 reference

Ras GTPase activating protein 1 Dmel_CG6721

1 reference

1 reference

Barry J Thompson

2

0 references

author name string

Wei Zhang

series ordinal

1

1 reference

PubMed ID

22242005

31 July 2017

Ville Hietakangas

series ordinal

3

1 reference

PubMed ID

22242005

31 July 2017

Stephen M Cohen

series ordinal

4

1 reference

31 July 2017

29 December 2011

1 reference

31 July 2017

1 reference

31 July 2017

7

1 reference

31 July 2017

e1002429

1 reference

31 July 2017

12

1 reference

Creative Commons Attribution 4.0 International

31 July 2017

start time

29 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3248469/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Kibra is a regulator of the Salvador/Warts/Hippo signaling network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Molecular mechanisms of metabolic regulation by insulin in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Regulation of tissue growth through nutrient sensing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

A microRNA imparts robustness against environmental fluctuation during development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

c-Jun N-terminal kinase pathways in diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Dynamic FoxO transcription factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

AKT/PKB signaling: navigating downstream

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Network motifs: theory and experimental approaches

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

The MEK/ERK cascade: from signaling specificity to diverse functions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

TOR signaling in growth and metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Transcriptional feedback control of insulin receptor by dFOXO/FOXO1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Role of protein kinase B in insulin-regulated glucose uptake.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Akt regulates growth by directly phosphorylating Tsc2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

KSR is a scaffold required for activation of the ERK/MAPK module

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Critical contribution of linker proteins to Raf kinase activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

The regulation of trehalose metabolism in insects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

Phosphatidylinositol-3-OH kinase as a direct target of Ras

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

The ETS domain protein pointed-P2 is a target of MAP kinase in the sevenless signal transduction pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248469

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002429

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002429

Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002429

Pointed regulates an eye-specific transcriptional enhancer in the Drosophila hedgehog gene, which is required for the movement of the morphogenetic furrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002429

Input from Ras is required for maximal PI(3)K signalling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002429

21 January 2018

The metabolic syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22242005

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1002429

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

PubMed ID

22242005