(Q29820880)

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

MAP kinase kinase activity

1 reference

24 April 2018

p38 MAPK signalling cascades: ancient roles and new functions

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977

protein serine/threonine/tyrosine kinase activity

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

protein tyrosine kinase activity

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

MAP-kinase scaffold activity

1 reference

8 April 2019

Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

2 references

JUN kinase kinase activity

3 references

24 April 2018

Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977

24 April 2018

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977

24 April 2018

hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

JUN kinase kinase activity

IPI

4 references

8 April 2019

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

p38 MAPK signalling cascades: ancient roles and new functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

establishment of planar polarity

NAS

1 reference

8 April 2019

Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

multicellular organism development

NAS

protein phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

border follicle cell migration

1 reference

24 April 2018

A sensitized PiggyBac-based screen for regulators of border cell migration in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977

regulation of mitotic cell cycle

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977

4 references

8 April 2019

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

The Drosophila serine protease homologue Scarface regulates JNK signalling in a negative-feedback loop during epithelial morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

Planar polarity and actin dynamics in the epidermis of Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

JNK signalling influences intracellular trafficking during Drosophila morphogenesis through regulation of the novel target gene Rab30.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

dorsal closure, spreading of leading edge cells

1 reference

8 April 2019

hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

Axon injury and regeneration in the adult Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

determination of adult lifespan

IDA

1 reference

8 April 2019

JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

positive regulation of autophagy

1 reference

8 April 2019

JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

positive regulation of lamellipodium assembly

1 reference

8 April 2019

Planar polarity and actin dynamics in the epidermis of Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

positive regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

chorion-containing eggshell pattern formation

1 reference

8 April 2019

The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

positive regulation of actin filament bundle assembly

1 reference

8 April 2019

Planar polarity and actin dynamics in the epidermis of Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

Control of metabolic homeostasis by stress signaling is mediated by the lipocalin NLaz.

carbohydrate homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

basement membrane disassembly

1 reference

8 April 2019

Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

melanization defense response

1 reference

8 April 2019

Crystal cell rupture after injury in Drosophila requires the JNK pathway, small GTPases and the TNF homolog Eiger

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

intestinal stem cell homeostasis

1 reference

8 April 2019

Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

JNK signaling pathway required for wound healing in regenerating Drosophila wing imaginal discs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

regulation of apoptotic process

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977

positive regulation of JUN kinase activity

1 reference

8 April 2019

Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

engulfment of apoptotic cell

1 reference

8 April 2019

Draper acts through the JNK pathway to control synchronous engulfment of dying germline cells by follicular epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

regulation of hemocyte differentiation

1 reference

10 September 2018

A directed screen for genes involved in Drosophila blood cell activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

positive regulation of JNK cascade

1 reference

8 April 2019

D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

Invasive cell behavior during Drosophila imaginal disc eversion is mediated by the JNK signaling cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

dorsal appendage formation

1 reference

8 April 2019

The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

chorion micropyle formation

1 reference

8 April 2019

The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

A signaling network for patterning of neuronal connectivity in the Drosophila brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

imaginal disc-derived male genitalia morphogenesis

1 reference

8 April 2019

The Drosophila serine protease homologue Scarface regulates JNK signalling in a negative-feedback loop during epithelial morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

positive regulation of filopodium assembly

1 reference

8 April 2019

Planar polarity and actin dynamics in the epidermis of Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

Control of metabolic homeostasis by stress signaling is mediated by the lipocalin NLaz.

triglyceride homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

cellular response to arsenic-containing substance

1 reference

8 April 2019

D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

cellular response to cadmium ion

1 reference

8 April 2019

D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

4 references

8 April 2019

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

imaginal disc fusion, thorax closure

4 references

8 April 2019

PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

JNK signalling influences intracellular trafficking during Drosophila morphogenesis through regulation of the novel target gene Rab30.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

The PP2C Alphabet is a negative regulator of stress-activated protein kinase signaling in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

8 April 2019

JNK signalling influences intracellular trafficking during Drosophila morphogenesis through regulation of the novel target gene Rab30.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

stress-activated protein kinase signaling cascade

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

activation of protein kinase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

positive regulation of border follicle cell migration

1 reference

8 April 2019

A sensitized PiggyBac-based screen for regulators of border cell migration in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

vascular endothelial growth factor receptor signaling pathway

1 reference

8 April 2019

PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977

serine/threonine-protein kinase, active site

has part(s)

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference