(Q29871434)

9 May 2017

A mammalian homolog of the zebrafish transmembrane protein 2 (TMEM2) is the long-sought-after cell-surface hyaluronidase (English)

1 reference

Cell migration inducing hyaluronidase 2

9 May 2017

transmembrane protein

0 references

1 reference

hyaluronan catabolic process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Hayato Yamamoto

1

1 reference

9 May 2017

Yuki Tobisawa

2

1 reference

9 May 2017

Toshihiro Inubushi

3

1 reference

9 May 2017

Fumitoshi Irie

4

1 reference

9 May 2017

Chikara Ohyama

5

1 reference

9 May 2017

Yu Yamaguchi

6

1 reference

9 May 2017

language of work or name

English

0 references

publication date

28 February 2017

1 reference

9 May 2017

10

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

9 May 2017

292

1 reference

9 May 2017

18

1 reference

9 May 2017

7304-7313

1 reference

HYAL2, a human gene expressed in many cells, encodes a lysosomal hyaluronidase with a novel type of specificity

9 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Mutations in HYAL1, a member of a tandemly distributed multigene family encoding disparate hyaluronidase activities, cause a newly described lysosomal disorder, mucopolysaccharidosis IX

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Identification of a hyaluronidase, Hyal5, involved in penetration of mouse sperm through cumulus mass

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

KIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerization

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migration

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

The crystal structure of pectate lyase Pel9A from Erwinia chrysanthemi

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

G8: a novel domain associated with polycystic kidney disease and non-syndromic hearing loss

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

GG: a domain involved in phage LTF apparatus and implicated in human MEB and non-syndromic hearing loss diseases

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

The structure of Bacillus subtilis pectate lyase in complex with calcium

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Mutations in the gene encoding KIAA1199 protein, an inner-ear protein expressed in Deiters’ cells and the fibrocytes, as the cause of nonsyndromic hearing loss

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

The Refined Three-Dimensional Structure of Pectate Lyase C from Erwinia chrysanthemi at 2.2 Angstrom Resolution (Implications for an Enzymatic Mechanism)

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Glycosyltransferases: structures, functions, and mechanisms

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Expression and cellular localization of human hyaluronidase-2 in articular chondrocytes and cultured cell lines

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation

10 May 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Structure of a plant cell wall fragment complexed to pectate lyase C

10 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Hyaluronan: A modulator of the tumor microenvironment

12 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

N-Terminal signal sequence is required for cellular trafficking and hyaluronan-depolymerization of KIAA1199.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

The novel transmembrane protein Tmem2 is essential for coordination of myocardial and endocardial morphogenesis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Involvement of hyaluronidases in colorectal cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Two novel functions of hyaluronidase-2 (Hyal2) are formation of the glycocalyx and control of CD44-ERM interactions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Clinicopathologic significance of KIAA1199 overexpression in human gastric cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

The many ways to cleave hyaluronan.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Hyaluronidases: their genomics, structures, and mechanisms of action

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Expression and characterization of a soluble, active form of the jaagsiekte sheep retrovirus receptor, Hyal2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Devising a pathway for hyaluronan catabolism: are we there yet?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

The dual functions of GPI-anchored PH-20: hyaluronidase and intracellular signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Purification and characterization of human serum hyaluronidase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Turnover and metabolism of hyaluronan

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418033

Expression of PH-20 in normal and neoplastic breast tissue.

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Transmembrane protein 2 (Tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Group-specific primer and probe sets to detect methanogenic communities using quantitative real-time polymerase chain reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.770149

Letter to the Editor: Hyal2, where are you?

21 January 2018

1 reference

12 December 2020

PH20: a novel tumor marker for laryngeal cancer

1 reference

12 December 2020

Versican/PG-M is essential for ventricular septal formation subsequent to cardiac atrioventricular cushion development

1 reference

12 December 2020

The Three-Dimensional Structure of Pectate Lyase E, a Plant Virulence Factor from Erwinia chrysanthemi

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M116.770149

1 reference

9 May 2017

0 references

1 reference