(Q30009968)

21 May 2017

title

Direct regulation of nephrin tyrosine phosphorylation by Nck adaptor proteins (English)

1 reference

21 May 2017

1 reference

Laura A New

1

1 reference

21 May 2017

Ava Keyvani Chahi

series ordinal

2

1 reference

21 May 2017

Nina Jones

series ordinal

3

1 reference

21 May 2017

language of work or name

English

0 references

publication date

27 November 2012

1 reference

Journal of Biological Chemistry

21 May 2017

published in

1 reference

21 May 2017

volume

288

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21 May 2017

issue

3

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21 May 2017

page(s)

1500-1510

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Cooperative interactions at the SLP-76 complex are critical for actin polymerization

21 May 2017

cites work

1 reference

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Specificity determinants of a novel Nck interaction with the juxtamembrane domain of the epidermal growth factor receptor

22 May 2017

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Regulation of FynT function by dual domain docking on PAG/Cbp

22 May 2017

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Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization

22 May 2017

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Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF

22 May 2017

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Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

22 May 2017

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Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility

22 May 2017

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Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling

22 May 2017

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Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin

22 May 2017

1 reference

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SAP couples Fyn to SLAM immune receptors

22 May 2017

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Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor

22 May 2017

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Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways

22 May 2017

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Cofilin-1 in the podocyte: a molecular switch for actin dynamics

22 May 2017

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3 June 2018

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c-mip impairs podocyte proximal signaling and induces heavy proteinuria

3 June 2018

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Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture

3 June 2018

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Nephrin-signature molecule of the glomerular podocyte?

3 June 2018

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The cofilin activity cycle in lamellipodia and invadopodia

3 June 2018

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Nck proteins maintain the adult glomerular filtration barrier

3 June 2018

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Nck adapter proteins: functional versatility in T cells

3 June 2018

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Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.

3 June 2018

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The XLP syndrome protein SAP interacts with SH3 proteins to regulate T cell signaling and proliferation

3 June 2018

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Neph1, a component of the kidney slit diaphragm, is tyrosine-phosphorylated by the Src family tyrosine kinase and modulates intracellular signaling by binding to Grb2.

3 June 2018

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Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548463

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity

3 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548463

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

3 June 2018

1 reference

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Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548463

SAP increases FynT kinase activity and is required for phosphorylation of SLAM and Ly9.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548463

Cell biology of the glomerular podocyte

3 June 2018

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3 June 2018

1 reference

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Activation of the Abl tyrosine kinase in vivo by Src homology 3 domains from the Src homology 2/Src homology 3 adaptor Nck.

3 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548463

The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.

3 June 2018

1 reference

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Stability and leakiness: opposing challenges to the glomerulus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548463

Physical and functional interactions between SH2 and SH3 domains of the Src family protein tyrosine kinase p59fyn

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548463

Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes.

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.439463

SRC-family kinase Fyn phosphorylates the cytoplasmic domain of nephrin and modulates its interaction with podocin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M112.439463

Decreased tyrosine phosphorylation of nephrin in rat and human nephrosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M112.439463

Glomerular proteins related to slit diaphragm and matrix adhesion in the foot processes are highly tyrosine phosphorylated in the normal rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.439463

Rat nephrin modulates cell morphology via the adaptor protein Nck

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23188823