(Q30175876)

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The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling

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Europe PubMed Central

PubMed publication ID

9 June 2017

The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 June 2017

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author name string

Denny MF

1

1 reference

Europe PubMed Central

PubMed publication ID

9 June 2017

Kaufman HC

2

1 reference

Europe PubMed Central

PubMed publication ID

9 June 2017

Chan AC

3

1 reference

Europe PubMed Central

PubMed publication ID

9 June 2017

Straus DB

4

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Europe PubMed Central

PubMed publication ID

9 June 2017

language of work or name

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publication date

1 February 1999

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Europe PubMed Central

PubMed publication ID

9 June 2017

number of pages

7

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

9 June 2017

274

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Europe PubMed Central

PubMed publication ID

9 June 2017

8

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Europe PubMed Central

PubMed publication ID

9 June 2017

5146-5152

1 reference

Europe PubMed Central

PubMed publication ID

9 June 2017

Signal transduction by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

T cell antigen receptor signal transduction pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Complex complexes: signaling at the TCR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Sequence requirements for induction of cytolysis by the T cell antigen/Fc receptor zeta chain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Role of protein kinase C in T-cell antigen receptor regulation of p21ras: evidence that two p21ras regulatory pathways coexist in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Activation of phosphatidylinositol-3-kinase in Jurkat T cells depends on the presence of the p56lck tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Effects of p56lck deficiency on the growth and cytolytic effector function of an interleukin-2-dependent cytotoxic T-cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Essential role for ZAP-70 in both positive and negative selection of thymocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Activating and Inhibitory Mutations in Adjacent Tyrosines in the Kinase Domain of ZAP-70

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Identification of a ten-amino acid proline-rich SH3 binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Rapid T-cell receptor-mediated tyrosine phosphorylation of p120, an Fyn/Lck Src homology 3 domain-binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, Hck

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Structure of the regulatory domains of the Src-family tyrosine kinase Lck

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Role of the Lck Src homology 2 and 3 domains in protein tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Physical and functional interactions between SH2 and SH3 domains of the Src family protein tyrosine kinase p59fyn

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Similarity of sli-1 , a Regulator of Vulval Development in C. elegans , to the Mammalian Proto-Oncogene c- cbl

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Tyrosyl Phosphorylation and Activation of MAP Kinases by p56lck

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Binding of human immunodeficiency virus type 1 to CD4 induces association of Lck and Raf-1 and activates Raf-1 by a Ras-independent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Association between mitogen-activated protein kinase and the zeta chain of the T cell receptor (TcR) with the SH2,3 domain of p56lck. Differential regulation by TcR cross-linking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Crystal structure of the Src family tyrosine kinase Hck

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Three-dimensional structure of the tyrosine kinase c-Src

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

SH3 domains specifically regulate kinase activity of expressed Src family proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Selective requirement for MAP kinase activation in thymocyte differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Involvement of p21ras activation in T cell CD69 expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5146

21 January 2018

Identifiers

10.1074/JBC.274.8.5146

1 reference

Europe PubMed Central

PubMed publication ID

9 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 June 2017

ResearchGate publication ID

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