(Q30311966)

English

Obese Patients with Polycystic Ovary Syndrome: Evidence that Metformin Does Not Restore Sensitivity of the Gonadotropin-Releasing Hormone Pulse Generator to Inhibition by Ovarian Steroids

scientific article published on November 1, 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

Obese patients with polycystic ovary syndrome: evidence that metformin does not restore sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by ovarian steroids (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

Obese Patients with Polycystic Ovary Syndrome: Evidence that Metformin Does Not Restore Sensitivity of the Gonadotropin-Releasing Hormone Pulse Generator to Inhibition by Ovarian Steroids (English)

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

0 references

polycystic ovary syndrome

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

polycystic ovary

1 reference

based on heuristic

inferred from title

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

author name string

Kathy Hu

3

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

Christine A. Eagleson

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14602743

29 March 2024

Amy B. Bellows

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14602743

29 March 2024

Melissa B. Gingrich

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14602743

29 March 2024

John C. Marshall

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14602743

29 March 2024

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publication date

1 November 2003

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

full work available at URL

The Journal of Clinical Endocrinology and Metabolism

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Europe PubMed Central

PubMed publication ID

16 June 2017

88

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Europe PubMed Central

PubMed publication ID

16 June 2017

11

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Europe PubMed Central

PubMed publication ID

16 June 2017

5158-5162

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

The epidemiology of polycystic ovary syndrome. Prevalence and associated disease risks

3

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Polycystic ovary syndrome

4

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Insulin and the polycystic ovary syndrome

5

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10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Insulin action in the polycystic ovary syndrome

6

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Polycystic Ovary Syndrome as a Form of FunctionalOvarian Hyperandrogenism Due to Dysregulation ofAndrogen Secretion*

8

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Insulin stimulates androgen accumulation in incubations of ovarian stroma obtained from women with hyperandrogenism

11

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Suppression of serum insulin by diazoxide reduces serum testosterone levels in obese women with polycystic ovary syndrome

13

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy

14

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Effects of metformin on insulin resistance, risk factors for cardiovascular disease, and plasminogen activator inhibitor in NIDDM subjects. A study of two ethnic groups.

15

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects.

16

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Metformin treatment reduces ovarian cytochrome P-450c17alpha response to human chorionic gonadotrophin in women with insulin resistance-related polycystic ovary syndrome.

17

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: a randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation.

18

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Effects of metformin on gonadotropin-induced ovulation in women with polycystic ovary syndrome

19

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Metformin-induced resumption of normal menses in 39 of 43 (91%) previously amenorrheic women with the polycystic ovary syndrome.

20

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Effects of the insulin sensitizing drug metformin on ovarian function, follicular growth and ovulation rate in obese women with oligomenorrhoea.

21

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

The effects of metformin on insulin resistance and ovarian steroidogenesis in women with polycystic ovary syndrome

22

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Therapeutic effects of metformin on insulin resistance and hyperandrogenism in polycystic ovary syndrome

23

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Metformin therapy improves the menstrual pattern with minimal endocrine and metabolic effects in women with polycystic ovary syndrome.

24

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome

25

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Menstrual cyclicity after metformin therapy in polycystic ovary syndrome.

27

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome

28

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Polycystic ovary syndrome

30

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Resistance of gonadotropin releasing hormone drive to sex steroid-induced suppression in hyperandrogenic anovulation.

32

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Suitability for use in population studies

34

1 reference

10.1210/JC.2003-030167

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29 March 2024

The pituitary gland secretes in bursts: appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations

36

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection

37

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Hypothalamic regulation of cyclic ovulation: evidence that the increase in gonadotropin-releasing hormone pulse frequency during the follicular phase reflects the gradual loss of the restraining effects of progesterone

38

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

40

1 reference

10.1210/JC.2003-030167

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29 March 2024

Effects of Exogenous Testosterone on Ovarian Weight, Follicular Morphology and Intraovarian Progesterone Concentration in Estrogen-Primed Hypophysectomized Immature Female Rats

41

1 reference

10.1210/JC.2003-030167

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29 March 2024

Evidence for a Role of Androgens in Follicular Maturation

42

1 reference

10.1210/JC.2003-030167

https://api.crossref.org/works/10.1210/JC.2003-030167

29 March 2024

Identifiers

10.1210/JC.2003-030167

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2017

ResearchGate publication ID

0 references

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