(Q30319286)

17 June 2017

title

Actions of aldosterone in the cardiovascular system: the good, the bad, and the ugly? (English)

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17 June 2017

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Michael Gekle

1

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17 June 2017

Claudia Grossmann

series ordinal

2

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17 June 2017

publication date

19 November 2008

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17 June 2017

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17 June 2017

volume

458

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17 June 2017

issue

2

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17 June 2017

page(s)

231-246

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Plasma ouabain-like factor during acute and chronic changes in sodium balance in essential hypertension.

17 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0616-0

ET(A) receptor antagonist prevents blood pressure elevation and vascular remodeling in aldosterone-infused rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0616-0

Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0616-0

Aldosterone induces a vascular inflammatory phenotype in the rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0616-0

Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK1/2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0616-0

Aldosterone-induced inflammation in the rat heart : role of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0616-0

Aldosterone interaction with epidermal growth factor receptor signaling in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0616-0

Limitation of Excessive Extracellular Matrix Turnover May Contribute to Survival Benefit of Spironolactone Therapy in Patients With Congestive Heart Failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0616-0

Mineralocorticoids upregulate arterial contraction to epidermal growth factor

21 January 2018

1 reference

12 December 2020

Aldosterone-sensitive neurons in the rat central nervous system

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12 December 2020

Nongenomic actions of steroid hormones

1 reference

12 December 2020

Spironolactone reduces cerebral infarct size and EGF-receptor mRNA in stroke-prone rats

1 reference

12 December 2020

Rapid nongenomic effects of aldosterone on the renal vasculature in humans

1 reference

12 December 2020

Rapid actions of aldosterone in vascular health and disease--friend or foe?

1 reference

12 December 2020

50th anniversary of aldosterone

1 reference

12 December 2020

Myocardial production of aldosterone and corticosterone in the rat. Physiological regulation

1 reference

12 December 2020

Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure

1 reference

12 December 2020

Aldosterone Inhibits Inducible Nitric Oxide Synthase in Neonatal Rat Cardiomyocytes

1 reference

12 December 2020

Hypertension, kidney, and transgenics: a fresh perspective

1 reference

12 December 2020

Mineralocorticoid receptor antagonism prevents the electrical remodeling that precedes cellular hypertrophy after myocardial infarction.

1 reference

12 December 2020

Crystal structure of an ancient protein: evolution by conformational epistasis

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12 December 2020

EF domains are sufficient for nongenomic mineralocorticoid receptor actions

1 reference

12 December 2020

Effect of aldosterone blockade in patients with systolic left ventricular dysfunction: implications of the RALES and EPHESUS studies

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12 December 2020

11beta-hydroxysteroid dehydrogenase type 2 activity in hypothalamic paraventricular nucleus modulates sympathetic excitation

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12 December 2020

Isolation from the adrenals of a new crystalline hormone with especially high effectiveness on mineral metabolism

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12 December 2020

Aldosterone stimulates collagen gene expression and synthesis via activation of ERK1/2 in rat renal fibroblasts

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12 December 2020

Advances in genetic hypertension

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12 December 2020

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy

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12 December 2020

Regulation of renin: new evidence from cultured cells and genetically modified mice

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12 December 2020

A direct relationship between plasma aldosterone and cardiac L-type Ca2+ current in mice

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12 December 2020

Central infusion of aldosterone synthase inhibitor prevents sympathetic hyperactivity and hypertension by central Na+ in Wistar rats

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12 December 2020

Aldosterone increases T-type calcium channel expression and in vitro beating frequency in neonatal rat cardiomyocytes.

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12 December 2020

Aldosterone and the vasculature: mechanisms mediating resistant hypertension

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12 December 2020

Early nongenomic events in aldosterone action in renal collecting duct cells: PKCalpha activation, mineralocorticoid receptor phosphorylation, and cross-talk with the genomic response.

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12 December 2020

Aldosterone--a hormone of cardiovascular adaptation and maladaptation

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12 December 2020

Aldosterone induces angiotensin converting enzyme gene expression via a JAK2-dependent pathway in rat endothelial cells

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12 December 2020

Mineralocorticoid Receptor Blockade But Not Steroid Withdrawal Reverses Renal Fibrosis in Deoxycorticosterone/Salt Rats

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12 December 2020

Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias

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12 December 2020

Aldosterone nongenomically worsens ischemia via protein kinase C-dependent pathways in hypoperfused canine hearts

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12 December 2020

Aldosterone-induced changes in the cardiac L-type Ca(2+) current can be prevented by antioxidants in vitro and are absent in rats on low salt diet

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12 December 2020

Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage

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12 December 2020

RETARDATION OF SODIUM EXCHANGE IN DOG ERYTHROCYTES BY PHYSIOLOGICAL CONCENTRATIONS OF ALDOSTERONE, IN VITRO.

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12 December 2020

Paradoxical mineralocorticoid receptor activation and left ventricular diastolic dysfunction under high oxidative stress conditions.

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12 December 2020

Interaction of rapid nongenomic cardiovascular aldosterone effects with the adrenergic system

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12 December 2020

Increased expression of mineralocorticoid effector mechanisms in kidney biopsies of patients with heavy proteinuria

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12 December 2020

Origin and physiological roles of inflammation

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12 December 2020

Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction

1 reference

12 December 2020

Mineralocorticoid excess, dietary sodium, and myocardial fibrosis

1 reference

12 December 2020

Eplerenone blocks nongenomic effects of aldosterone on the Na+/H+ exchanger, intracellular Ca2+ levels, and vasoconstriction in mesenteric resistance vessels

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12 December 2020

Aldosterone modulates I(f) current through gene expression in cultured neonatal rat ventricular myocytes

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12 December 2020

DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor-mediated transcription in hippocampal cells--toward a basis for the opposite actions elicited by two nuclear receptors?

1 reference

12 December 2020

Myocardial fibrosis: role of angiotensin II and aldosterone

1 reference

12 December 2020

Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart

1 reference

12 December 2020

Regulation of the human Na/K-ATPase beta1 gene promoter by mineralocorticoid and glucocorticoid receptors

1 reference

12 December 2020

Human epidermal growth factor receptor-1 expression renders Chinese hamster ovary cells sensitive to alternative aldosterone signaling

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12 December 2020

Cardioprotective mechanisms of spironolactone associated with the angiotensin-converting enzyme/epidermal growth factor receptor/extracellular signal-regulated kinases, NAD(P)H oxidase/lectin-like oxidized low-density lipoprotein receptor-1, and Rho

1 reference

12 December 2020

Aldosterone, through novel signaling proteins, is a fundamental molecular bridge between the genetic defect and the cardiac phenotype of hypertrophic cardiomyopathy

1 reference

12 December 2020

Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor

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12 December 2020

Effects of adrenomedullin on cardiac oxidative stress and collagen accumulation in aldosterone-dependent malignant hypertensive rats

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12 December 2020

Angiotensin II-induced growth of vascular smooth muscle cells requires an Src-dependent activation of the epidermal growth factor receptor

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12 December 2020

Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker

1 reference

12 December 2020

Plasma marinobufagenin-like and ouabain-like immunoreactivity during saline volume expansion in anesthetized dogs

1 reference

12 December 2020

Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload

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12 December 2020

Vascular ENaC proteins are required for renal myogenic constriction

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12 December 2020

Plasminogen activator inhibitor-1 deficiency protects against aldosterone-induced glomerular injury

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12 December 2020

c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats

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12 December 2020

Mechanisms for aldosterone and spironolactone-induced positive inotropic actions in the rat heart

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12 December 2020

Human mineralocorticoid receptor expression renders cells responsive for nongenotropic aldosterone actions

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12 December 2020

Mineralocorticoid receptor blockade attenuates chronic overexpression of the renin-angiotensin-aldosterone system stimulation of reduced nicotinamide adenine dinucleotide phosphate oxidase and cardiac remodeling.

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12 December 2020

Rapid inhibition of vasoconstriction in renal afferent arterioles by aldosterone.

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12 December 2020

Direct and indirect effects of aldosterone on cyclooxygenase-2 and interleukin-6 expression in rat cardiac cells in culture and after myocardial infarction.

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12 December 2020

Differential regulation of 11beta-hydroxysteroid dehydrogenase type-1 and -2 gene transcription by proinflammatory cytokines in vascular smooth muscle cells

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12 December 2020

Effects of adrenomedullin on aldosterone-induced cell proliferation in rat cardiac fibroblasts

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12 December 2020

Arterial epidermal growth factor receptor expression in deoxycorticosterone acetate-salt hypertension

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12 December 2020

How does salt retention raise blood pressure?

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12 December 2020

Rapid natriuretic action of aldosterone in the rat.

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12 December 2020

Epidermal growth factor receptor trans-activation mediates the tonic and fibrogenic effects of endothelin in the aortic wall of transgenic mice

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12 December 2020

Central role for the cardiotonic steroid marinobufagenin in the pathogenesis of experimental uremic cardiomyopathy

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12 December 2020

Eplerenone, but not steroid withdrawal, reverses cardiac fibrosis in deoxycorticosterone/salt-treated rats

1 reference

12 December 2020

Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1.

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12 December 2020

Glucocorticoid-related signaling effects in vascular smooth muscle cells

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12 December 2020

Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells

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12 December 2020

Rapid nongenomic effects of aldosterone on human forearm vasculature

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12 December 2020

Aldosterone induces mesangial cell apoptosis both in vivo and in vitro

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12 December 2020

Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases

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12 December 2020

Aldosterone-induced EGFR expression: interaction between the human mineralocorticoid receptor and the human EGFR promoter

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12 December 2020

Rapid activation of Na+/H+-exchange in MDCK cells by aldosterone involves MAP-kinase ERK1/2.

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12 December 2020

Effect of spironolactone on cytosolic free sodium concentration in platelets from hypertensive patients with primary aldosteronism

1 reference

12 December 2020

Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation

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12 December 2020

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12 December 2020

Clinical experimental studies on the influence of aldosterone on hemodynamics and blod coagulation

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12 December 2020

Adenoviral-directed expression of the type 1A angiotensin receptor promotes cardiomyocyte hypertrophy via transactivation of the epidermal growth factor receptor

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12 December 2020

Does aldosterone upregulate the brain renin-angiotensin system in rats with heart failure?

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12 December 2020

Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats

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12 December 2020

Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways.

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12 December 2020

Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells

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12 December 2020

Aldosterone and D-glucose stimulate the proliferation of human cardiac myofibroblasts in vitro

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12 December 2020

The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators

1 reference

12 December 2020

Aldosterone upregulates Ca(2+) current in adult rat cardiomyocytes

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12 December 2020

Effects of aldosterone on transient outward K+ current density in rat ventricular myocytes

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12 December 2020

Renal damage in primary aldosteronism: results of the PAPY Study

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12 December 2020

Spironolactone improves angiotensin-induced vascular changes and oxidative stress

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12 December 2020

Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.

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12 December 2020

Direct effects of aldosterone on cardiomyocytes in the presence of normal and elevated extracellular sodium

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12 December 2020

Ca2+ but not H2O2 modulates GRE-element activation by the human mineralocorticoid receptor in HEK cells.

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12 December 2020

An angiotensin II type 1 receptor mutant lacking epidermal growth factor receptor transactivation does not induce angiotensin II-mediated cardiac hypertrophy

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12 December 2020

Targeted expression of a dominant-negative EGF-R in the kidney reduces tubulo-interstitial lesions after renal injury

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12 December 2020

Rapid activation of Na+/H+ exchange by aldosterone in renal epithelial cells requires Ca2+ and stimulation of a plasma membrane proton conductance

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12 December 2020

Aldosterone induces contraction of the resistance arteries in man.

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12 December 2020

Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats

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12 December 2020

Identification of a mineralocorticoid/glucocorticoid response element in the human Na/K ATPase alpha1 gene promoter

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12 December 2020

Marinobufagenin interferes with the function of the mineralocorticoid receptor

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12 December 2020

Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling

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12 December 2020

Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes.

1 reference

12 December 2020

Renal ischemia-reperfusion injury is prevented by the mineralocorticoid receptor blocker spironolactone

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12 December 2020

Antisense to epidermal growth factor receptor prevents the development of left ventricular hypertrophy

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12 December 2020

Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system

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12 December 2020

Aldosterone stimulates matrix metalloproteinases and reactive oxygen species in adult rat ventricular cardiomyocytes

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12 December 2020

Molecular mechanisms of myocardial remodeling. The role of aldosterone

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12 December 2020

Activation of cardiac aldosterone production in rat myocardial infarction: effect of angiotensin II receptor blockade and role in cardiac fibrosis

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12 December 2020

Cardioprotective mechanisms of eplerenone on cardiac performance and remodeling in failing rat hearts

1 reference

12 December 2020

Aldosterone blunts human baroreflex sensitivity by a nongenomic mechanism

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12 December 2020

Rapid aldosterone-induced cell volume increase of endothelial cells measured by the atomic force microscope

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12 December 2020

Rapid cardiovascular action of aldosterone in man.

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12 December 2020

Cardiac specific increase in aldosterone production induces coronary dysfunction in aldosterone synthase-transgenic mice.

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12 December 2020

Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase

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12 December 2020

Marinobufagenin stimulates fibroblast collagen production and causes fibrosis in experimental uremic cardiomyopathy

1 reference

12 December 2020

The mineralocorticoid receptor: a journey exploring its diversity and specificity of action

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12 December 2020

Aldosterone and angiotensin II synergistically induce mitogenic response in vascular smooth muscle cells

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12 December 2020

Rate of change in sodium and potassium excretion after injection of aldosterone into the aorta and renal artery of the dog

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12 December 2020

Aldosterone regulates vascular reactivity: short-term effects mediated by phosphatidylinositol 3-kinase-dependent nitric oxide synthase activation

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12 December 2020

Aldosterone induces elastin production in cardiac fibroblasts through activation of insulin-like growth factor-I receptors in a mineralocorticoid receptor-independent manner

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12 December 2020

Aldosterone and amiloride alter ENaC abundance in vascular endothelium

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12 December 2020

Corticosteroids and redox potential modulate spontaneous contractions in isolated rat ventricular cardiomyocytes

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12 December 2020

Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth

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12 December 2020

Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress

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12 December 2020

Angiotensin II-induced cardiac hypertrophy and hypertension are attenuated by epidermal growth factor receptor antisense.

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12 December 2020

Non-genomic action of the mineralocorticoid aldosterone on cytosolic sodium in cultured kidney cells

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12 December 2020

Direct action of aldosterone on transmembrane 22Na efflux from arterial smooth muscle. Rapid and delayed effects

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12 December 2020

Centrally mediated effects of sodium and angiotensin II on arterial blood pressure and fluid balance.

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12 December 2020

The nongenomic actions of aldosterone

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12 December 2020

Influence of aldosterone on collagen synthesis and proliferation of rat cardiac fibroblasts

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12 December 2020

Aldosterone stimulates epidermal growth factor receptor expression

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12 December 2020

Evidence for epidermal growth factor receptor as negative-feedback control in aldosterone-induced Na+ reabsorption

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12 December 2020

Altered collagen homeostasis in human aortic smooth muscle cells (HAoSMCs) induced by aldosterone.

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12 December 2020

Sodium transport parameters in erythrocytes of patients with primary aldosteronism

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12 December 2020

Non-classical actions of the mineralocorticoid receptor: misuse of EGF receptors?

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12 December 2020

Conditional glucocorticoid receptor expression in the heart induces atrio-ventricular block

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12 December 2020

Plasma sodium stiffens vascular endothelium and reduces nitric oxide release.

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12 December 2020

Critical role of CNS effects of aldosterone in cardiac remodeling post-myocardial infarction in rats

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12 December 2020

Involvement of oxidative stress in the profibrotic action of aldosterone. Interaction wtih the renin-angiotension system

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12 December 2020

Collagen metabolism in cultured adult rat cardiac fibroblasts: response to angiotensin II and aldosterone

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12 December 2020

10.1007/S00424-008-0616-0

Identifiers

DOI

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Dimensions Publication ID

17 June 2017

1026256952

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