(Q30333364)

18 June 2017

title

Key substrate recognition residues in the active site of a plant cytochrome P450, CYP73A1. Homology guided site-directed mutagenesis. (English)

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18 June 2017

Guillaume A Schoch

1

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18 June 2017

Roger Attias

series ordinal

2

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18 June 2017

Monique Le Ret

series ordinal

3

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18 June 2017

Danièle Werck-Reichhart

series ordinal

4

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18 June 2017

language of work or name

English

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publication date

1 September 2003

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18 June 2017

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18 June 2017

volume

270

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18 June 2017

issue

18

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18 June 2017

page(s)

3684-3695

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Phenylpropanoid biosynthesis and its regulation

18 June 2017

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Novel characteristics and regulation of a divergent cinnamate 4-hydroxylase (CYP73A15) from French bean: engineering expression in yeast.

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Role of unusual amino acid residues in the proximal and distal heme regions of a plant P450, CYP73A1.

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Purification and characterization of the NADPH-cytochrome P-450 (cytochrome c) reductase from higher-plant microsomal fraction

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Two cytochrome P-450 isoforms catalysing O-de-ethylation of ethoxycoumarin and ethoxyresorufin in higher plants

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Backbone-dependent rotamer library for proteins. Application to side-chain prediction

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A single amino acid substitution (F363I) converts the regiochemistry of the spearmint (-)-limonene hydroxylase from a C6- to a C3-hydroxylase

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Elucidation of amino acid residues critical for unique activities of rabbit cytochrome P450 2B5 using hybrid enzymes and reciprocal site-directed mutagenesis with rabbit cytochrome P450 2B4.

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Identification of three key residues in substrate recognition site 5 of human cytochrome P450 3A4 by cassette and site-directed mutagenesis.

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21 January 2018

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Crystal structure and refinement of cytochrome P450terp at 2.3 A resolution

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Design of fluorescent substrates and potent inhibitors of CYP73As, P450s that catalyze 4-hydroxylation of cinnamic acid in higher plants

21 January 2018

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Piperonylic acid, a selective, mechanism-based inactivator of the trans-cinnamate 4-hydroxylase: A new tool to control the flux of metabolites in the phenylpropanoid pathway

21 January 2018

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21 January 2018

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21 January 2018

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Interaction of aflatoxin B1 with cytochrome P450 2A5 and its mutants: correlation with metabolic activation and toxicity

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Rational re-design of the substrate binding site of flavocytochrome P450 BM3

21 January 2018

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10.1046/J.1432-1033.2003.03739.X

21 January 2018

Identifiers

DOI

1 reference

18 June 2017

1 reference