(Q30357869)

English

Infertility in Female Mice with a Gain-of-Function Mutation in the Luteinizing Hormone Receptor Is Due to Irregular Estrous Cyclicity, Anovulation, Hormonal Alterations, and Polycystic Ovaries.

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Infertility in Female Mice with a Gain-of-Function Mutation in the Luteinizing Hormone Receptor Is Due to Irregular Estrous Cyclicity, Anovulation, Hormonal Alterations, and Polycystic Ovaries. (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Lan Hai

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Stacey R McGee

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Amanda C Rabideau

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Marilène Paquet

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Prema Narayan

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

1 reference

Biology of Reproduction

publication date

3 June 2015

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Biology of Reproduction

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

93

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

16

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Precocious puberty and Leydig cell hyperplasia in male mice with a gain of function mutation in the LH receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Ovulation involves the luteinizing hormone-dependent activation of G(q/11) in granulosa cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Animal models of polycystic ovary syndrome: a focused review of rodent models in relationship to clinical phenotypes and cardiometabolic risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Rodent models for human polycystic ovary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Novel signaling mechanisms in the ovary during oocyte maturation and ovulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Mutation analysis of the LH receptor gene in Leydig cell adenoma and hyperplasia and functional and biochemical studies of activating mutations of the LH receptor gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

The ovary: basic biology and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Female mice expressing constitutively active mutants of FSH receptor present with a phenotype of premature follicle depletion and estrogen excess

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

A delayed gonadotropin-dependent and growth factor-mediated activation of the extracellular signal-regulated kinase 1/2 cascade negatively regulates aromatase expression in granulosa cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

An update of the pathophysiology of human gonadotrophin subunit and receptor gene mutations and polymorphisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Multiple sites of tumorigenesis in transgenic mice overproducing hCG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Quantitative magnetic resonance (QMR) method for bone and whole-body-composition analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Consequences of elevated luteinizing hormone on diverse physiological systems: use of the LHbetaCTP transgenic mouse as a model of ovarian hyperstimulation-induced pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Novel signaling pathways that control ovarian follicular development, ovulation, and luteinization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

The Lutropin/Choriogonadotropin Receptor, A 2002 Perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Mutations of follicle stimulating hormone-beta and its receptor in human and mouse: genotype/phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Luteinizing hormone induction of ovarian tumors: oligogenic differences between mouse strains dictates tumor disposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Elevated luteinizing hormone in prepubertal transgenic mice causes hyperandrogenemia, precocious puberty, and substantial ovarian pathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

The role of Asp578 in maintaining the inactive conformation of the human lutropin/choriogonadotropin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Molecular aspects of the ontogeny of the pituitary-gonadal axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Targeted overexpression of luteinizing hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

Hormonal control of gene expression in the ovary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

The ovarian androgen producing cells: a review of structure/function relationships

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

3 June 2018

The lutropin/choriogonadotropin receptor, a 2002 perspective

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.115.129072

21 January 2018

Reproductive and metabolic phenotype of a mouse model of PCOS.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.115.129072

21 January 2018

Formation of cystic ovarian follicles associated with elevated luteinizing hormone requires estrogen receptor-beta

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.115.129072

21 January 2018

Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice.

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.115.129072

21 January 2018

Reproductive disturbances, pituitary lactotrope adenomas, and mammary gland tumors in transgenic female mice producing high levels of human chorionic gonadotropin

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.115.129072

21 January 2018

Gonadal defects and hormonal alterations in transgenic mice expressing a single chain human chorionic gonadotropin-lutropin receptor complex

1 reference

https://api.crossref.org/works/10.1095%2FBIOLREPROD.115.129072

21 January 2018

Transgenic mice with chronically elevated luteinizing hormone are infertile due to anovulation, defects in uterine receptivity, and midgestation pregnancy failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706306

26 November 2018

Development of luteinizing hormone action in the perinatal rat ovary

1 reference

https://pubmed.ncbi.nlm.nih.gov/26040673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response to challenge with gonadotropin-releasing hormone agonist in a mother and her two sons with a constitutively activating mutation of the luteinizing hormone receptor--a clinical research center study

1 reference

https://pubmed.ncbi.nlm.nih.gov/26040673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic models to study gonadotropin function: the role of follicle-stimulating hormone in gonadal growth and tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26040673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substitution of M398T in the second transmembrane helix of the LH receptor in a patient with familial male-limited precocious puberty

1 reference

https://pubmed.ncbi.nlm.nih.gov/26040673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Study of the family of a patient with male-limited precocious puberty (MPP) due to T1193C transition in exon 11 of LH receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/26040673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desensitization of Gs-coupled receptor signaling by constitutively active mutants of the human lutropin/choriogonadotropin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/26040673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity in transgenic female mice with constitutively elevated luteinizing hormone secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/26040673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1095/BIOLREPROD.115.129072

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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