(Q30360537)

English

Mutations at the dimer, hexamer, and receptor-binding surfaces of insulin independently affect insulin-insulin and insulin-receptor interactions

scientific article published on February 18, 1992

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scholarly article

1 reference

Europe PubMed Central

20 June 2017

Mutations at the dimer, hexamer, and receptor-binding surfaces of insulin independently affect insulin-insulin and insulin-receptor interactions (English)

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

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based on heuristic

inferred from title

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

author name string

S. E. Shoelson

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1737029

12 November 2022

Z. X. Lu

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1737029

12 November 2022

L. Parlautan

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1737029

12 November 2022

C. S. Lynch

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1737029

12 November 2022

M. A. Weiss

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1737029

12 November 2022

language of work or name

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publication date

1 February 1992

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Europe PubMed Central

20 June 2017

18 February 1992

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1737029

12 November 2022

number of pages

11

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full work available at URL

https://pubs.acs.org/doi/pdf/10.1021/bi00121a025

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

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Europe PubMed Central

20 June 2017

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1757-1767

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Europe PubMed Central

20 June 2017

Structure of Rhombohedral 2 Zinc Insulin Crystals

1

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

[LeuB24]insulin and [AlaB24]insulin: altered structures and cellular processing of B24-substituted insulin analogs

2

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

The structure of 2Zn pig insulin crystals at 1.5 A resolution

3

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10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Zinc-free cubic pig insulin: crystallization and structure determination

4

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10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Atomic Positions in Rhombohedral 2-Zinc Insulin Crystals

6

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

1H n.m.r. studies of insulin. Assignment of resonances and properties of tyrosine residues

8

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Monomeric insulins obtained by protein engineering and their medical implications

9

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10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Monomeric insulins and their experimental and clinical implications

10

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10.1021/BI00121A025

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12 November 2022

Preparation and characterization of desoctapeptide-insulin

11

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10.1021/BI00121A025

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12 November 2022

Shortened insulin with enhanced in vitro potency

12

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Phenol stabilizes more helix in a new symmetrical zinc insulin hexamer

13

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue.

14

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cells

17

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

A shortened insulin with full in vitro potency

18

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Structure-function relationships of shortened [LeuB25]insulins, semisynthetic analogues of a mutant human insulin

19

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Insulin receptors: binding kinetics and structure-function relationship of insulin

20

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Zinc binding, circular dichroism, and equilibrium sedimentation studies on insulin (bovine) and several of its derivatives

21

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Familial hyperinsulinemia due to a structurally abnormal insulin. Definition of an emerging new clinical syndrome.

22

1 reference

10.1021/BI00121A025

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12 November 2022

Toward the solution structure of human insulin: sequential 2D 1H NMR assignment of a des-pentapeptide analogue and comparison with crystal structure

23

1 reference

10.1021/BI00121A025

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12 November 2022

Thermodynamic identification of stable folding intermediates in the B-subunit of cholera toxin

24

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

High resolution 1H-NMR studies of Des-(B26-B30)-insulin; assignment of resonances and properties of aromatic residues

25

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Receptor binding redefined by a structural switch in a mutant human insulin

26

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Semisynthesis and properties of some insulin analogs

29

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Semisynthesis and biological properties of the [B24-leucine]-, [B25-leucine[- and [B24-leucine, B25-leucine]-analogues of human insulin

30

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

An equilibrium ultracentrifuge study of the self-association of bovine insulin

32

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Self-association of des-(B26-B30)-insulin. The effect of Ca2+ and some other divalent cations

34

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Comparison of insulin analogue B9AspB27Glu and soluble human insulin in insulin-treated diabetes

35

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Comparison of subcutaneous soluble human insulin and insulin analogues (AspB9, GluB27; AspB10; AspB28) on meal-related plasma glucose excursions in type I diabetic subjects

36

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Subcutaneous Insulin Absorption Explained by Insulin's Physicochemical Properties: Evidence From Absorption Studies of Soluble Human Insulin and Insulin Analogues in Humans

37

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Complete sequence-specific 1H NMR assignments for human insulin

38

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Characterization of [LeuB-24]- and [LeuB-25]-insulin analogues. Receptor binding and biological activity

39

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Supernormal insulin: [D-PheB24]-insulin with increased affinity for insulin receptors

40

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Receptor binding and biological activity of [SerB24]-insulin, an abnormal mutant insulin

41

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Proton nuclear magnetic resonance study of the B9(Asp) mutant of human insulin. Sequential assignment and secondary structure.

42

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

International journal of peptide and protein research

43

27

514

author name string

Kubrick T.

publication date

1986

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Soluble, prolonged-acting insulin derivatives. III. Degree of protraction, crystallizability and chemical stability of insulins substituted in positions A21, B13, B23, B27 and B30

45

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Disposition of the phenylalanine B25 side chain during insulin-receptor and insulin-insulin interactions

47

1 reference

10.1021/BI00121A025

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12 November 2022

Conformation of proinsulin. A comparison of insulin and proinsulin self-association at neutral pH.

51

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Receptor-binding region of insulin

53

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

The semisynthesis of portions of hen's-egg lysozyme by fragment condensation

54

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

A superactive insulin: [B10-aspartic acid]insulin(human).

56

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

A highly potent insulin: des-(B26-B30)-[AspB10,TyrB25-NH2]insulin(human).

57

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Identification of a mutant human insulin predicted to contain a serine-for-phenylalanine substitution

59

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Three mutant insulins in man

60

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model

61

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Binding kinetics of mutated insulin receptors in transfected cells grown in suspension culture: application to the Tyr----Phe 960 insulin receptor mutant

63

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Structural stability in the 4-zinc human insulin hexamer

64

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Near-ultraviolet tyrosyl circular dichroism of pig insulin monomers, dimers, and hexamers. Dipole-dipole coupling calculations in the monopole approximation

66

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

A structurally abnormal insulin causing human diabetes

67

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Semisynthesis and biological activity of porcine [LeuB24]insulin and [LeuB25]insulin

68

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Two-dimensional NMR and photo-CIDNP studies of the insulin monomer: assignment of aromatic resonances with application to protein folding, structure, and dynamics

69

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Heteronuclear 2D NMR studies of an engineered insulin monomer: assignment and characterization of the receptor-binding surface by selective 2H and 13C labeling with application to protein design

70

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Two mutant forms of human insulin. Structural consequences of the substitution of invariant B24- or B25-phenylalanine by leucine

72

1 reference

10.1021/BI00121A025

https://api.crossref.org/works/10.1021/BI00121A025

12 November 2022

Identifiers

10.1021/BI00121A025

1 reference

Europe PubMed Central

20 June 2017

1 reference

Europe PubMed Central

20 June 2017

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