(Q30387202)

21 June 2017

title

Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins (English)

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21 June 2017

author name string

Somasekhar Bondalapati

series ordinal

1

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21 June 2017

Muhammad Jbara

series ordinal

2

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21 June 2017

Ashraf Brik

series ordinal

3

1 reference

21 June 2017

publication date

1 April 2016

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21 June 2017

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21 June 2017

volume

8

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21 June 2017

issue

5

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21 June 2017

page(s)

407-418

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Rethinking amide bond synthesis

21 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemical synthesis of peptides and proteins

21 January 2018

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Synthesis of proteins by native chemical ligation

21 January 2018

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Chemoselective ligation and modification strategies for peptides and proteins.

21 January 2018

1 reference

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Chemical and semisynthesis of posttranslationally modified proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Racemic protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Semisynthesis of proteins by expressed protein ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Protein semi-synthesis: new proteins for functional and structural studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Kinetically controlled ligation for the convergent chemical synthesis of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

In Situ Neutralization in Boc-chemistry Solid Phase Peptide Synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Peptide and protein thioester synthesis via N-->S acyl transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Development of new thioester equivalents for protein chemical synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

An efficient Fmoc-SPPS approach for the generation of thioester peptide precursors for use in native chemical ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

A reversible protection strategy to improve Fmoc-SPPS of peptide thioesters by the N-Acylurea approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemical Protein Synthesis Using a Second-Generation N-Acylurea Linker for the Preparation of Peptide-Thioester Precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Convergent chemical synthesis of histone H2B protein for the site-specific ubiquitination at Lys34.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Synthesis and folding of a mirror-image enzyme reveals ambidextrous chaperone activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Towards biomolecular assembly employing extended native chemical ligation in combination with thioester synthesis using an N-->S acyl shift

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Sequential native peptide ligation strategies for total chemical protein synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemical synthesis of biologically active monoglycosylated GM2-activator protein analogue using N-sulfanylethylanilide peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Bis(2-sulfanylethyl)amino native peptide ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Peptidyl N,N-bis(2-mercaptoethyl)-amides as thioester precursors for native chemical ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Total synthesis of cytochrome b562 by native chemical ligation using a removable auxiliary

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Extending synthetic access to proteins with a removable acyl transfer auxiliary.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Free-radical-based, specific desulfurization of cysteine: a powerful advance in the synthesis of polypeptides and glycopolypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

One-pot total chemical synthesis of human α-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemistry as an expanding resource in protein science: fully synthetic and fully active human parathyroid hormone-related protein (1-141).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemical synthesis of the ATAD2 bromodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemical synthesis of homogeneous human glycosyl-interferon-β that exhibits potent antitumor activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

At last: erythropoietin as a single glycoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

The winding pathway to erythropoietin along the chemistry-biology frontier: a success at last.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Erythropoietin derived by chemical synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Highly efficient and chemoselective peptide ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemistry and biology of the ubiquitin signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Peptide o-aminoanilides as crypto-thioesters for protein chemical synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

A one-pot total synthesis of crambin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Convergent chemical synthesis and crystal structure of a 203 amino acid "covalent dimer" HIV-1 protease enzyme molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Protein conformational dynamics in the mechanism of HIV-1 protease catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Ionization state of the catalytic dyad Asp25/25' in the HIV-1 protease: NMR studies of site-specifically 13C labelled HIV-1 protease prepared by total chemical synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Convergent versus sequential protein synthesis: the case of ubiquitinated and glycosylated H2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemical synthesis and expression of the HIV-1 Rev protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Trifluoroethanethiol: an additive for efficient one-pot peptide ligation-desulfurization chemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Acceleration of thiol additive-free native chemical ligation by intramolecular S → S acyl transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Traceless purification and desulfurization of tau protein ligation products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemical Protein Synthesis by Solid Phase Ligation of Unprotected Peptide Segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Protein synthesis by solid-phase chemical ligation using a safety catch linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Towards the simplification of protein synthesis: iterative solid-supported ligations with concomitant purifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Solid phase chemical ligation employing a rink amide linker for the synthesis of histone H2B protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Self-assembled templates for polypeptide synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

A "traceless" Staudinger ligation for the chemoselective synthesis of amide bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Staudinger ligation: a peptide from a thioester and azide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Critical evaluation and rate constants of chemoselective ligation reactions for stoichiometric conjugations in water

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Protein chemical synthesis by serine and threonine ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Traceless preparation of C-terminal α-ketoacids for chemical protein synthesis by α-ketoacid-hydroxylamine ligation: synthesis of SUMO2/3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Targeting deubiquitinases enabled by chemical synthesis of proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Reconstitution of the catalytic core of F-ATPase (αβ)3γ from Escherichia coli using chemically synthesized subunit γ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Rapid flow-based peptide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chromatin modifications and their function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Traceless ligation of cysteine peptides using selective deselenization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Oxidative Deselenization of Selenocysteine: Applications for Programmed Ligation at Serine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Expedient total synthesis of small to medium-sized membrane proteins via Fmoc chemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Modular total chemical synthesis of a human immunodeficiency virus type 1 protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemical Synthesis of O-Glycosylated Human Interleukin-2 by the Reverse Polarity Protection Strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Delivery of mirror image polypeptides into cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Chemical tagging and customizing of cellular chromatin states using ultrafast trans-splicing inteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

Convergent chemical synthesis of proteins by ligation of peptide hydrazides

21 January 2018

1 reference

12 December 2020

Preformed selenoesters enable rapid native chemical ligation at intractable sites

1 reference

12 December 2020

Total chemical synthesis of a 304 amino acid K48-linked tetraubiquitin protein

1 reference

12 December 2020

Chemical synthesis of an erythropoietin glycoform containing a complex-type disialyloligosaccharide

1 reference

12 December 2020

Chemical synthesis of phosphorylated ubiquitin and diubiquitin exposes positional sensitivities of e1-e2 enzymes and deubiquitinases

1 reference

12 December 2020

Rapid additive-free selenocystine-selenoester peptide ligation

1 reference

12 December 2020

Rapid ligations with equimolar reactants in water with the potassium acyltrifluoroborate (KAT) amide formation

1 reference

12 December 2020

Chemical synthesis of ubiquitinated peptides with varying lengths and types of ubiquitin chains to explore the activity of deubiquitinases

1 reference

12 December 2020

Insights into the mechanism and catalysis of the native chemical ligation reaction

1 reference

12 December 2020

N-->S acyl-transfer-mediated synthesis of peptide thioesters using anilide derivatives

1 reference

12 December 2020

Protein chemical synthesis by ligation of peptide hydrazides

1 reference

12 December 2020

Polymerization behavior of a bifunctional ubiquitin monomer as a function of the nucleophile site and folding conditions

1 reference

12 December 2020

Antifreeze glycoproteins: elucidation of the structural motifs that are essential for antifreeze activity

1 reference

12 December 2020

Chemoselective amide ligations by decarboxylative condensations of N-alkylhydroxylamines and alpha-ketoacids

1 reference

12 December 2020

Total chemical synthesis of an integral membrane enzyme: diacylglycerol kinase from Escherichia coli

1 reference

12 December 2020

Total synthesis of homogeneous antifreeze glycopeptides and glycoproteins

1 reference

12 December 2020

An oxazetidine amino acid for chemical protein synthesis by rapid, serine-forming ligations

1 reference

12 December 2020

Synthesis of thiazolidine thioester peptides and acceleration of native chemical ligation

1 reference

12 December 2020

In situ neutralization in Boc-chemistry solid phase peptide synthesis. Rapid, high yield assembly of difficult sequences

1 reference

12 December 2020

Nonenzymatic polyubiquitination of expressed proteins

1 reference

12 December 2020

Insights into the deselenization of selenocysteine into alanine and serine

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.2476

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCHEM.2476

1 reference

Dimensions Publication ID

21 June 2017

1000986871

0 references

1 reference