(Q30410617)

13 October 2017

Soyasaponins can blunt inflammation by inhibiting the reactive oxygen species-mediated activation of PI3K/Akt/NF-kB pathway (English)

1 reference

13 October 2017

0 references

reactive oxygen species

1 reference

Longying Zha

1

1 reference

13 October 2017

Jiading Chen

2

1 reference

13 October 2017

Suxia Sun

3

1 reference

13 October 2017

Limei Mao

4

1 reference

13 October 2017

Xinwei Chu

5

1 reference

13 October 2017

Hong Deng

6

1 reference

13 October 2017

Junwei Cai

7

1 reference

13 October 2017

Xuefeng Li

8

1 reference

13 October 2017

Zhenqi Liu

9

1 reference

13 October 2017

Wenhong Cao

10

1 reference

13 October 2017

language of work or name

English

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publication date

18 September 2014

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13 October 2017

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13 October 2017

9

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13 October 2017

9

1 reference

13 October 2017

e107655

1 reference

Creative Commons Attribution 4.0 International

13 October 2017

start time

18 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

20 June 2018

1 reference

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Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer

20 June 2018

1 reference

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Anti-inflammatory effect of soyasaponins through suppressing nitric oxide production in LPS-stimulated RAW 264.7 cells by attenuation of NF-κB-mediated nitric oxide synthase expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Excess exposure to insulin is the primary cause of insulin resistance and its associated atherosclerosis

20 June 2018

1 reference

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Regulation of autophagy by ROS: physiology and pathology

20 June 2018

1 reference

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Non-isoflavone phytochemicals in soy and their health effects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 signaling

20 June 2018

1 reference

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Functional food targeting the regulation of obesity-induced inflammatory responses and pathologies.

20 June 2018

1 reference

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Macrophages, inflammation, and insulin resistance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Chemical and biological characterization of oleanane triterpenoids from soy.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Management of cardiovascular disease risk in chronic inflammatory disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Effect of soyasapogenol A and soyasapogenol B concentrated extracts on HEP-G2 cell proliferation and apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Targeting the AKT protein kinase for cancer chemoprevention

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Asthma and insulin resistance in morbidly obese children and adolescents.

20 June 2018

1 reference

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Obesity in psoriasis: the metabolic, clinical and therapeutic implications. Report of an interdisciplinary conference and review

20 June 2018

1 reference

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Soyasaponins inhibit the proliferation of Hela cells by inducing apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism

20 June 2018

1 reference

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The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk

20 June 2018

1 reference

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The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's Disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Exploiting the PI3K/AKT pathway for cancer drug discovery

20 June 2018

1 reference

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Molecular targets of dietary polyphenols with anti-inflammatory properties

20 June 2018

1 reference

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IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy

20 June 2018

1 reference

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Inflammation-associated cancer: NF-kappaB is the lynchpin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Soy saponins and the anticancer effects of soybeans and soy-based foods

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Mode of action of endotoxin: role of free radicals and antioxidants

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Hepatoprotective constituents in plants. 14. Effects of soyasapogenol B, sophoradiol, and their glucuronides on the cytotoxicity of tert-butyl hydroperoxide to HepG2 cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Soybeans, Soy Foods, Isoflavones and Risk of Colorectal Cancer: a Review of Experimental and Epidemiological Data

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

20 June 2018

Inflammation and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Characterization and antimutagenic activity of soybean saponins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Legumes and soybeans: overview of their nutritional profiles and health effects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Inhibitory activity of soyasaponin II on virus replication in vitro

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Soy intake and cancer risk: a review of the in vitro and in vivo data

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Inhibitory effect of glycosides like saponin from soybean on the infectivity of HIV in vitro

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Could saponins be a useful treatment for hypercholesterolaemia?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Soy consumption, markers of inflammation, and endothelial function: a cross-over study in postmenopausal women with the metabolic syndrome.

20 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107655

Soy protein intake, cardiorenal indices, and C-reactive protein in type 2 diabetes with nephropathy: a longitudinal randomized clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107655

Protective effect of soybean saponins and major antioxidants against aflatoxin B1-induced mutagenicity and DNA-adduct formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107655

Soybean saponins suppress the release of proinflammatory mediators by LPS-stimulated peritoneal macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107655

Soyasaponin I attenuates TNBS-Induced colitis in mice by inhibiting NF-κB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107655

Lipopolysaccharide activates Akt in vascular smooth muscle cells resulting in induction of inducible nitric oxide synthase through nuclear factor-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107655

Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107655

Peripheral insulin and brain structure in early Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107655

Soyasaponins lowered plasma cholesterol and increased fecal bile acids in female golden Syrian hamsters

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169425

Soyfood intake and breast cancer survival: a followup of the Shanghai Breast Cancer Study

26 November 2018

1 reference

12 December 2020

[Links between osteoporosis and atherosclerosis; beyond insulin resistance]

1 reference

12 December 2020

Effects of soyasaponins on lipid peroxidation through the secretion of thyroid hormones

1 reference

12 December 2020

Structure-hepatoprotective relationships study of soyasaponins I-IV having soyasapogenol B as aglycone

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0107655

Identifiers

DOI

1 reference

13 October 2017

0 references

1 reference

13 October 2017

PubMed publication ID

25233217

1 reference