(Q30415535)

22 August 2017

1 reference

title

T-type calcium channel blockers as neuroprotective agents (English)

1 reference

22 August 2017

Benjamin J Kopecky

1

1 reference

22 August 2017

Ruqiang Liang

series ordinal

2

1 reference

22 August 2017

Jianxin Bao

series ordinal

3

1 reference

22 August 2017

25 February 2014

1 reference

22 August 2017

1 reference

22 August 2017

466

1 reference

22 August 2017

4

1 reference

22 August 2017

757-765

1 reference

T-type Ca2+ channels in normal and abnormal brain functions

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Prophylactic and therapeutic functions of drug combinations against noise-induced hearing loss

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Retracted: Neurotoxicity Induced by Bupivacaine via T-Type Calcium Channels in SH-SY5Y Cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Mitochondrial Ca2+ uptake from plasma membrane Cav3.2 protein channels contributes to ischemic toxicity in PC12 cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

T-type Ca2+ channel blocker, KYS05047 induces G1 phase cell cycle arrest by decreasing intracellular Ca2+ levels in human lung adenocarcinoma A549 cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Modulation of low-voltage-activated T-type Ca²⁺ channels.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Zonisamide in the treatment of epilepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Signaling complexes of voltage-gated calcium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Neuronal T-type calcium channels: what's new? Iftinca: T-type channel regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Anti-epileptic drugs delay age-related loss of spiral ganglion neurons via T-type calcium channel

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Comparative trial of low- and high-dose zonisamide as monotherapy for childhood epilepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Verapamil block of T-type calcium channels.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

In vitro characterization of T-type calcium channel antagonist TTA-A2 and in vivo effects on arousal in mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

The antiepileptic drug zonisamide inhibits MAO-B and attenuates MPTP toxicity in mice: clinical relevance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Neuroprotective effects of blockers for T-type calcium channels.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Neurons that fire together also conspire together: is normal sleep circuitry hijacked to generate epilepsy?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Ebselen attenuates cisplatin-induced ROS generation through Nrf2 activation in auditory cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

T-type calcium channels regulate cortical plasticity in-vivo. [corrected]

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Zonisamide block of cloned human T-type voltage-gated calcium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Regulation of neuronal T-type calcium channels.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Mechanisms and functional significance of inhibition of neuronal T-type calcium channels by isoflurane

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Molecular pharmacology of human Cav3.2 T-type Ca2+ channels: block by antihypertensives, antiarrhythmics, and their analogs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Differential interactions of Na+ channel toxins with T-type Ca2+ channels.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Evidence that cisplatin-induced auditory damage is attenuated by downregulation of pro-inflammatory cytokines via Nrf2/HO-1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Upregulation of the T-type calcium current in small rat sensory neurons after chronic constrictive injury of the sciatic nerve

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Making the T-type even tinier: corticotropin-releasing factor-mediated inhibition of low-voltage-activated calcium channel activity.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Activation of corticotropin-releasing factor receptor 1 selectively inhibits CaV3.2 T-type calcium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Trazodone inhibits T-type calcium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Regulation of T-type calcium channels by Rho-associated kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Thalamic synchrony and dynamic regulation of global forebrain oscillations.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Prophylactic and therapeutic functions of T-type calcium blockers against noise-induced hearing loss

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Lead discovery and optimization of T-type calcium channel blockers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Ca(V)3 T-type calcium channel isoforms differentially distribute to somatic and dendritic compartments in rat central neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Subunit-specific modulation of T-type calcium channels by zinc.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Specific T-type calcium channel isoforms are associated with distinct burst phenotypes in deep cerebellar nuclear neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Zonisamide add-on for drug-resistant partial epilepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Voltage-dependent calcium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Protective effect of T-type calcium channel blocker flunarizine on cisplatin-induced death of auditory cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Inhibition of T-type calcium channels protects neurons from delayed ischemia-induced damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Voltage gated ion channels: targets for anticonvulsant drugs.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

5beta-reduced neuroactive steroids are novel voltage-dependent blockers of T-type Ca2+ channels in rat sensory neurons in vitro and potent peripheral analgesics in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Rescue of mesencephalic dopaminergic neurons in culture by low-level stimulation of voltage-gated sodium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Low-voltage-activated ("T-Type") calcium channels in review

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Actions of sipatrigine, 202W92 and lamotrigine on R-type and T-type Ca2+ channel currents

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Store-operated calcium channel regulates the chemotactic behavior of ascidian sperm

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Efonidipine hydrochloride: a dual blocker of L- and T-type ca(2+) channels.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Differential inhibition of T-type calcium channels by neuroleptics.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Neuroprotective actions in vivo and electrophysiological actions in vitro of 202W92.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Block of cloned human T-type calcium channels by succinimide antiepileptic drugs.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Structural determinants of fast inactivation of high voltage-activated Ca(2+) channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Pharmacological properties of T-type Ca2+ current in adult rat sensory neurons: effects of anticonvulsant and anesthetic agents

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Destabilization of ionized Ca2+ homeostasis in excitatory amino acid neurotoxicity: antagonism by glycosphingolipids.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Interaction of T-Type Calcium Channel CaV3.3 with the β-Subunit

20 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Common mechanisms of drug interactions with sodium and T-type calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

A critical role of NO/cGMP/PKG dependent pathway in hippocampal post-ischemic LTP: modulation by zonisamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Five different profiles of dihydropyridines in blocking T-type Ca(2+) channel subtypes (Ca(v)3.1 (alpha(1G)), Ca(v)3.2 (alpha(1H)), and Ca(v)3.3 (alpha(1I))) expressed in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Combined L-/T-type calcium channel blockers: ready for prime time.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Protective role of Nrf2 in age-related hearing loss and gentamicin ototoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Neuroprotection by lomerizine, a prophylactic drug for migraine, against hydrogen peroxide-induced hippocampal neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Efficacy and tolerability of adjunctive therapy with zonisamide in childhood intractable epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Glutamate increases toxicity of inorganic lead in GT1-7 neurons: partial protection induced by flunarizine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

ECNP Summit on the future of CNS drug research in Europe 2011: report prepared for ECNP by David Nutt and Guy Goodwin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Pyridyl amides as potent inhibitors of T-type calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Synthesis and anticonvulsant activity of aromatic tetramethylcyclopropanecarboxamide derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Role of the alpha1G T-type calcium channel in spontaneous absence seizures in mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

T-type calcium channels are inhibited by fluoxetine and its metabolite norfluoxetine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

L-type voltage-gated calcium channel is involved in the pathogenesis of acoustic injury in the cochlea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

The patterns of anticoagulation control and the risk of stroke, bleeding and mortality in patients with non-valvular atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Upregulation of T-type Ca2+ channels in primary sensory neurons in spinal nerve injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Zonisamide attenuates MPP+-induced oxidative toxicity through modulation of Ca2+ signaling and caspase-3 activity in neuronal PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-014-1454-X

Ca(v)3.2 channel is a molecular substrate for inhibition of T-type calcium currents in rat sensory neurons by nitrous oxide

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

Pharmacological properties of the T-type Ca2+ current of mouse spermatogenic cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4005039

The neuroprotective effects of intrathecal administration of the selective N-type calcium channel blocker ziconotide in a rat model of spinal ischemia

26 November 2018

1 reference

12 December 2020

Drug regulatory systems must foster innovation

1 reference

12 December 2020

Two structurally different T-type Ca 2+ channel inhibitors, mibefradil and pimozide, protect CA1 neurons from delayed death after global ischemia in rats

1 reference

12 December 2020

Thalamic ryanodine receptors are involved in controlling the tonic firing of thalamocortical neurons and inflammatory pain signal processing

1 reference

12 December 2020

Zonisamide up-regulated the mRNAs encoding astrocytic anti-oxidative and neurotrophic factors

1 reference

12 December 2020

10.1007/S00424-014-1454-X

Identifiers

DOI

1 reference

Dimensions Publication ID

22 August 2017

0 references

1 reference

22 August 2017

PubMed publication ID

24563219

1 reference