(Q30420056)

English

G-protein-coupled receptor kinase interactor-1 (GIT1) is a new endothelial nitric-oxide synthase (eNOS) interactor with functional effects on vascular homeostasis.

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scholarly article

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Europe PubMed Central

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21 January 2020

G-protein-coupled receptor kinase interactor-1 (GIT1) is a new endothelial nitric-oxide synthase (eNOS) interactor with functional effects on vascular homeostasis (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22294688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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G protein-coupled receptor

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Richard T Premont

2

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21 January 2020

author name string

Songling Liu

1

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21 January 2020

Don C Rockey

3

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21 January 2020

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publication date

31 January 2012

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21 January 2020

number of pages

12

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inferred from page(s)

Journal of Biological Chemistry

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21 January 2020

287

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21 January 2020

15

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Europe PubMed Central

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21 January 2020

12309-12320

1 reference

Europe PubMed Central

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21 January 2020

G protein coupled receptor kinase 2 interacting protein 1 (GIT1) is a novel regulator of mitochondrial biogenesis in heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Life history of eNOS: partners and pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Functions of G protein-coupled receptor kinase interacting protein 1 in human neuronal (NT2N) cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Identification of phosphorylation sites in GIT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

The multifunctional GIT family of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Regulation of neuroendocrine exocytosis by the ARF6 GTPase-activating protein GIT1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

The regulation and pharmacology of endothelial nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Akt1 contains a functional leucine-rich nuclear export sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

The GIT/PIX complex: an oligomeric assembly of GIT family ARF GTPase-activating proteins and PIX family Rac1/Cdc42 guanine nucleotide exchange factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Talin: an emerging focal point of adhesion dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

GIT1 functions as a scaffold for MEK1-extracellular signal-regulated kinase 1 and 2 activation by angiotensin II and epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

GIT1 Mediates Src-dependent Activation of Phospholipase Cγ by Angiotensin II and Epidermal Growth Factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Regulation of endothelial nitric oxide synthase: location, location, location

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in Golgi and plasma membrane defines the existence of two pools of active enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by beta-adrenergic receptor kinase 1. A role in receptor sequestration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

NOSIP, a novel modulator of endothelial nitric oxide synthase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Direct interaction between endothelial nitric-oxide synthase and dynamin-2. Implications for nitric-oxide synthase function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Dynamin mediates caveolar sequestration of muscarinic cholinergic receptors and alteration in NO signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

GIT proteins, A novel family of phosphatidylinositol 3,4, 5-trisphosphate-stimulated GTPase-activating proteins for ARF6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Estradiol induces the calcium-dependent translocation of endothelial nitric oxide synthase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Dynamic activation of endothelial nitric oxide synthase by Hsp90.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Endothelial Ca2+ waves preferentially originate at specific loci in caveolin-rich cell edges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Absence of endothelin receptors and receptor mRNA in mammalian fibroblasts transformed with SV40 or ras oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Acylation targets emdothelial nitric-oxide synthase to plasmalemmal caveolae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Endothelial nitric oxide synthase. N-terminal myristoylation determines subcellular localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Nitric oxide and its role in the cardiovascular system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320980

20 June 2018

Estrogen-induced vasoprotection is estrogen receptor dependent: evidence from the balloon-injured rat carotid artery model.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.320465

21 January 2018

Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.320465

21 January 2018

Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.320465

21 January 2018

Adenovirus-mediated gene transfer to nonparenchymal cells in normal and injured liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.320465

21 January 2018

Endothelial nitric oxide synthase and its negative regulator caveolin-1 localize to distinct perinuclear organelles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.320465

21 January 2018

ACh-induced endothelial NO synthase translocation, NO release and vasodilatation in the hamster microcirculation in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.320465

21 January 2018

eNOS translocation but not eNOS phosphorylation is dependent on intracellular Ca2+ in human atrial myocardium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.320465

21 January 2018

S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK, and paxillin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.320465

21 January 2018

Calcium-dependent nitric oxide synthesis in endothelial cytosol is mediated by calmodulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22294688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22294688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A chimeric transmembrane domain directs endothelial nitric-oxide synthase palmitoylation and targeting to plasmalemmal caveolae

1 reference

https://pubmed.ncbi.nlm.nih.gov/22294688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/22294688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/22294688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electron transfer and catalytic activity of nitric oxide synthases. Chimeric constructs of the neuronal, inducible, and endothelial isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/22294688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor-regulated translocation of endothelial nitric-oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22294688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of flow-dependent endothelial nitric-oxide synthase phosphorylation sites by mass spectrometry and regulation of phosphorylation and nitric oxide production by the phosphatidylinositol 3-kinase inhibitor LY294002

1 reference

https://pubmed.ncbi.nlm.nih.gov/22294688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.320465

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22294688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22294688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22294688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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