(Q30420719)

21 June 2017

1 reference

title

Regulatory mechanisms in the activation of nitrogenous compounds by mammalian cytochrome P-450 isozymes (English)

1 reference

21 June 2017

Hlavica P

1

1 reference

PubMed ID

8082573

21 June 2017

language of work or name

English

0 references

publication date

1 January 1994

1 reference

21 June 2017

Drug Metabolism Reviews

1 reference

21 June 2017

26

1 reference

21 June 2017

1-2

1 reference

21 June 2017

325-348

1 reference

Binding of nitrogen containing compounds to microsomal cytochromes

21 June 2017

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Substrate interaction with cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Comparative Studies on theN-Oxidation of Aniline andN,N-Dimethylaniline by Rabbit Liver Microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Quantitative analysis of the spin equilibrium of cytochrome P-450 LM-2 fraction from rabbit liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

The demonstration of both type I and type II components in the difference spectra produced by aniline and N-ethylaniline with cytochrome P-450

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

The role of hydrophobicity and electronic factors in regulating alcohol inhibition of cytochrome P-450-mediated aniline hydroxylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

A role for phospholipids in the binding and metabolism of drugs by hepatic microsomes. Use of the fluorescent hydrophobic probe 1-anilinonaphthalene-8-sulphonate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Evidence for lipid involvement in the high-affinity interaction between cimetidine and rat liver cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Effect of phenobarbital and 3-methylcholanthrene administration in vivo and isooctane extraction in vitro on metyrapone binding to reduced cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Effects of storage on hepatic microsomal cytochromes and substrate-induced difference spectra

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Effect of phenobarbital and 3,4-benzpyrene treatment of rats on the microsomal binding and hydroxylation of nortriptyline and desmethyl-imipramine: evidence for qualitative changes in cytochrome P-450-ligand interaction following phenobarbital pretr

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Effect of phenobarbital and 3-methylcholanthrene administration on the in vitro enhancement of microsomal aromatic hydroxylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

A three-dimensional molecular template for substrates of human cytochrome P450 involved in debrisoquine 4-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Active site model of cytochrome P-450 LM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Substrate access channel geometry of soluble and membrane-bound cytochromes P450 as studied by interactions with type II substrate analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Topological mapping of the active sites of cytochromes P4502B1 and P4502B2 by in situ rearrangement of aryl-iron complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Effect of mutations at Lys250, Arg251, and Lys253 of cytochrome P450 1A2 on the catalytic activities and the bindings of bifunctional axial ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Purification to homogeneity and enzymological characterization of a functional covalent complex composed of cytochromes P-450 isozyme 2 and b5 from rabbit liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Differences in the spectral interactions between NADPH-cytochrome P-450 reductase and a series of cytochrome P-450 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

The role of the stimulation of ANDPH-cytochrome P-450 reductase activity in hepatic, microsomal mixed function oxidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Kinetics of hepatic cytochrome P-450 reduction: correlation with spin state of the ferric heme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Reduction kinetics of purified rat liver cytochrome P-450. Evidence for a sequential reaction mechanism dependent on the hemoprotein spin state.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Spin state control of cytochrome P-450 reduction and catalytic activity in a reconstituted P-450 LM2 system as induced by a series of benzphetamine analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Spin state control of the hepatic cytochrome P450 redox potential

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

NADH-synergism of NADPH-dependent O-dealkylation of type II compounds, p-anisidine and p-phenetidine, in rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Nadh synergism of microsomal aniline metabolism in the presence of enhancing agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Electron transfer in the membranes of endoplasmic reticulum. Participation of cytochrome b5 in the NADPH oxidation reaction. The evidence for two cytochromes b5 in liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Influences of substrates of different microsomal electron transfer pathways on the oxidation-reduction kinetics of microsomal cytochrome b5

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent formation and breakdown of hydrogen peroxide during mixed function oxidation reactions in liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

The roles of cytochrome b5 in a reconstituted N-demethylase system containing cytochrome P-450

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Spectral intermediates in the reaction of oxygen with purified liver microsomal cytochrome P-450

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Cytochrome P-450 spin state and leakiness of the monooxygenase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Oxygen activation by cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Differentiation of various types of biological oxidation of nitrogen in organic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

The metabolism of amphetamine in vitro by rabbit liver preparations: a comparison of R(-) and S(+) enantiomers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Contributions of human liver cytochrome P450 enzymes to the N-oxidation of 4,4′-methylene-bis(2-chloroaniline)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Metabolic activation of mutagenic heterocyclic aromatic amines from protein pyrolysates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Metabolic processing of 2-acetylaminofluorene by microsomes and six highly purified cytochrome P-450 forms from rabbit liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Metabolism of 2-acetylaminofluorene by eight different forms of cytochrome P-450 isolated from rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Metabolism of hydrazine anti-cancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

The cytochromes P-448--a unique family of enzymes involved in chemical toxicity and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Comparative studies on the cumene hydroperoxide- and NADPH-supported N-oxidation of 4-chloroaniline by cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

N-hydroxylation of 4,4'-diaminodiphenylsulphone (Dapsone) by liver microsomes, and in dogs and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Matabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytochrome P450IIB1 in a reconstituted system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Induction of the alcohol-inducible form of cytochrome P-450 by nitrogen-containing heterocycles: effects on pyridine N-oxide production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Metabolism of cocaine and norcocaine to N-hydroxynorcocaine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Participation of cytochrome P-450 isozymes in N-demethylation, N-hydroxylation and aromatic hydroxylation of methamphetamine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Role of cytochrome P450IIIA4 in the metabolism of the pyrrolizidine alkaloid senecionine in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

N-oxygenation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent: the role of flavin-containing monooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Peroxidative N-oxidation and N-dealkylation reactions of pargyline

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Hydrogen peroxide-dependent liver microsomal N-demethylation and N-oxygenation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Cytochrome P-455 nm complex formation in the metabolism of phenylalkylamines. XI. Peroxygenase versus monooxygenase function of cytochrome P-450 in rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Studies on the cytochrome P-450 product complexes formed during the metabolism of N,N-dimethylaniline.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Interaction of ligands with cytochrome P-450. On the 442 nm spectral species generated during the oxidative metabolism of pyridine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

In vivo effects of erythromycin, oleandomycin and erythralosamine derivatives on hepatic cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Formation of Complexes between Microsomal Cytochrome P-450-Fe(II) and Nitrosoarenes Obtained by Oxidation of Arylhydroxylamines or Reduction of Nitroarenes in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

Evidence for the involvement of cytochrome P-450 in tiaramide N-oxide reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029801

10.3109/03602539409029801

21 January 2018

Identifiers

DOI

1 reference

21 June 2017

1 reference

PubMed ID

8082573