(Q30426495)

21 June 2017

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title

Antisense approaches to the gene therapy of cancer--'Recnac'. (English)

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21 June 2017

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Gibson I

1

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21 June 2017

publication date

1 September 1996

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Cancer and Metastasis Reviews

21 June 2017

published in

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21 June 2017

volume

15

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21 June 2017

issue

3

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21 June 2017

page(s)

287-299

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Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy

21 June 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF00046343

The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemia

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF00046343

Inhibition of gene expression by triple helix-directed DNA cross-linking at specific sites.

21 January 2018

1 reference

12 December 2020

Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide

1 reference

12 December 2020

The uptake kinetics of chimeric oligodeoxynucleotide analogues in human leukaemia MOLT-4 cells

1 reference

12 December 2020

Acute- and chronic-phase chronic myelogenous leukemia colony-forming units are highly sensitive to the growth inhibitory effects of c-myb antisense oligodeoxynucleotides

1 reference

12 December 2020

A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence

1 reference

12 December 2020

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

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12 December 2020

Introduction of antisense oligonucleotides into cells by permeabilization with streptolysin O

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12 December 2020

Pharmacokinetics, biodistribution, and stability of capped oligodeoxynucleotide phosphorothioates in mice

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12 December 2020

Intracellular distribution of microinjected antisense oligonucleotides

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12 December 2020

Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

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12 December 2020

Nuclease-resistant ribozymes decrease stromelysin mRNA levels in rabbit synovium following exogenous delivery to the knee joint

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12 December 2020

Antisense BCR-ABL oligonucleotides induce apoptosis in the Philadelphia chromosome-positive cell line BV173.

1 reference

12 December 2020

Antisense BCR-ABL oligomers cause non-specific inhibition of chronic myeloid leukemia cell lines

1 reference

12 December 2020

Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide

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12 December 2020

Problems in interpretation of data derived from in vitro and in vivo use of antisense oligodeoxynucleotides

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12 December 2020

Mechanism of oligonucleotide uptake by cells: involvement of specific receptors?

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12 December 2020

Characteristics of oligonucleotide uptake in human keratinocyte cultures

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12 December 2020

Ribozyme-mediated cleavage of the bcr/abl transcript expressed in chronic myeloid leukemia

1 reference

12 December 2020

Effects of sequence of thioated oligonucleotides on cultured human mammary epithelial cells.

1 reference

12 December 2020

Oligonucleotide clamps arrest DNA synthesis on a single-stranded DNA target

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12 December 2020

Optimization of antisense oligodeoxynucleotide structure for targeting bcr-abl mRNA

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12 December 2020

Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides

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12 December 2020

Renal disposition characteristics of oligonucleotides modified at terminal linkages in the perfused rat kidney.

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12 December 2020

Characterization of oligonucleotide transport into living cells

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12 December 2020

In vivostability and kinetics of absorption and disposition of 3' phosphopropyl amine oligonucleotides

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12 December 2020

Stability and Pharmacokinetic Characteristics of Oligonucleotides Modified at Terminal Linkages in Mice

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12 December 2020

Generating loss-of-function phenotypes of the fushi tarazu gene with a targeted ribozyme in Drosophila.

1 reference

12 December 2020

Transient Expression Assay for Antisense RNAs Using Episomal Replication of Plasmids: Effective Reduction of Retinoblastoma Gene (Rb-1) Product by Its Antisense RNA Complementary to 3′-Untranslated Region

1 reference

12 December 2020

Ribozyme-mediated cleavage of the BCRABL oncogene transcript: in vitro cleavage of RNA and in vivo loss of P210 protein-kinase activity

1 reference

12 December 2020

Antisense inhibition of oncogene expression

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12 December 2020

Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: initial results of a phase I trial

1 reference

12 December 2020

The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism

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12 December 2020

Chimeric oligodeoxynucleotide analogues: enhanced cell uptake of structures which direct ribonuclease H with high specificity

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12 December 2020

Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity

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12 December 2020

In vitro and in vivo effects of synthetic ribozymes targeted against BCR/ABL mRNA

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12 December 2020

Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides.

1 reference

12 December 2020

Inhibition of protein-tyrosine kinase activity in intact cells by the aptameric action of oligodeoxynucleotides

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12 December 2020

To cleave or not to cleave: ribozymes and antisense.

1 reference

12 December 2020

Specific antiviral activity of a poly(L-lysine)-conjugated oligodeoxyribonucleotide sequence complementary to vesicular stomatitis virus N protein mRNA initiation site

1 reference

12 December 2020

Antisense oligonucleotides as therapeutic agents--is the bullet really magical?

1 reference

12 December 2020

Attenuation of white gene expression in transgenic Drosophila melanogaster: possible role of a catalytic antisense RNA.

1 reference

12 December 2020

Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences

1 reference

12 December 2020

Multi-unit ribozyme-mediated cleavage of bcr-abl mRNA in myeloid leukemias.

1 reference

12 December 2020

Phosphorothioate oligonucleotides reduce melanoma growth in a SCID-hu mouse model by a nonantisense mechanism

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12 December 2020

Mechanism of cellular uptake of modified oligodeoxynucleotides containing methylphosphonate linkages

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12 December 2020

Selective Inhibition of Leukemia Cell Proliferation by BCR-ABL Antisense Oligodeoxynucleotides

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12 December 2020

Short modified antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation

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12 December 2020

Inhibition of HIV-1 replication in cultured cells with antisense oligonucleotides encapsulated in immunoliposomes.

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12 December 2020

Oligonucleotide therapeutics: coming 'round the clubhouse turn

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12 December 2020

Antisense RNA-mediated inhibition of mouse hepatitis virus replication in L2 cells.

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12 December 2020

Tissue-specific expression of an anti-ras ribozyme inhibits proliferation of human malignant melanoma cells

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12 December 2020

Reversible covalent attachment of cholesterol to oligodeoxyribonucleotides for studies of the mechanisms of their penetration into eucaryotic cells.

1 reference

12 December 2020

Capping of bcr-abl antisense oligonucleotides enhances antiproliferative activity against chronic myeloid leukemia cell lines

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12 December 2020

Synthesis of phosphorothioate analogues of oligodeoxyribonucleotides and their antiviral activity against human immunodeficiency virus (HIV).

1 reference

12 December 2020

Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells

1 reference

12 December 2020

Influence of Chromosomal Position and Copy Number of awhite-Directed Ribozyme Gene on the Suppression of Eye Pigmentation inDrosophila melanogaster

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12 December 2020

Electroporation enhances c-myc antisense oligodeoxynucleotide efficacy

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12 December 2020

Ribozyme-mediated inhibition of bcr-abl gene expression in a Philadelphia chromosome-positive cell line.

1 reference

12 December 2020

Current concepts in antisense drug design

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12 December 2020

Liposomal delivery of methylphosphonate antisense oligodeoxynucleotides in chronic myelogenous leukemia

1 reference

12 December 2020

Aptameric inhibition of p210bcr-abl tyrosine kinase autophosphorylation by oligodeoxynucleotides of defined sequence and backbone structure

1 reference

12 December 2020

Simple RNA enzymes with new and highly specific endoribonuclease activities

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12 December 2020

Identifiers

DOI

10.1007/BF00046343

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Dimensions Publication ID

21 June 2017

1032052837

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