(Q30426593)

21 June 2017

title

P16 deletion and mutation analysis in human brain tumors (English)

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21 June 2017

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Barker FG

1

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21 June 2017

Chen P

2

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21 June 2017

Furman F

3

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21 June 2017

Aldape KD

4

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21 June 2017

Edwards MS

5

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21 June 2017

Israel MA

6

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21 June 2017

publication date

1 January 1997

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Journal of Neuro-Oncology

21 June 2017

published in

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21 June 2017

volume

31

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21 June 2017

issue

1-2

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21 June 2017

page(s)

17-23

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MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p

21 June 2017

cites work

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12 December 2020

The retinoblastoma gene is involved in malignant progression of astrocytomas

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12 December 2020

CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas.

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12 December 2020

Mutational analysis of CDKN2 (MTS1/p16ink4) in human breast carcinomas

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12 December 2020

Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas.

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12 December 2020

Loss in expression of the retinoblastoma gene product in human gliomas is associated with advanced disease

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12 December 2020

Localization of chromosome 9p homozygous deletions in glioma cell lines with markers constituting a continuous linkage group

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12 December 2020

Distinct deletions of chromosome 9p associated with melanoma versus glioma, lung cancer, and leukemia.

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12 December 2020

Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB

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12 December 2020

Retinoblastoma gene deletions in human glioblastomas

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12 December 2020

Differential inactivation of CDKN2 and Rb protein in non-small-cell and small-cell lung cancer cell lines.

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12 December 2020

Aberrations of p16Ink4 and retinoblastoma tumour-suppressor genes occur in distinct sub-sets of human cancer cell lines

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12 December 2020

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

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12 December 2020

Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma

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12 December 2020

Rates of p16 (MTS1) mutations in primary tumors with 9p loss

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12 December 2020

Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds

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12 December 2020

Constitutional p53 mutations associated with brain tumors in young adults

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12 December 2020

Germline p16 mutations in familial melanoma

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12 December 2020

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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12 December 2020

The multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 gene in human central nervous system primitive neuroectodermal tumor.

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12 December 2020

Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines.

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12 December 2020

Cell-cycle regulators and cancer

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12 December 2020

Molecular and cytogenetic analysis of chromosome 9 deletions in 75 malignant gliomas

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12 December 2020

Replacement of the p16/CDKN2 gene suppresses human glioma cell growth

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12 December 2020

Loss of P16INK4 expression is frequent in high grade gliomas.

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12 December 2020

CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines

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12 December 2020

Mutation rate of the CDKN2 gene in malignant gliomas.

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12 December 2020

MTS1/p16/CDKN2 lesions in primary glioblastoma multiforme.

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12 December 2020

Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck.

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12 December 2020

Deletion of p16 and p15 genes in brain tumors

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12 December 2020

A cell cycle regulator potentially involved in genesis of many tumor types

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12 December 2020

Identifiers

DOI

10.1023/A:1005768910871

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Dimensions Publication ID

21 June 2017

1001292746

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