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Double-mutant cycles: a powerful tool for analyzing protein structure and function
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9080186
retrieved
21 June 2017
title
Double-mutant cycles: a powerful tool for analyzing protein structure and function
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9080186
retrieved
21 June 2017
main subject
protein structure
0 references
author name string
Horovitz A
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9080186
retrieved
21 June 2017
publication date
1 January 1996
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stated in
Europe PubMed Central
PubMed ID
9080186
retrieved
21 June 2017
published in
Folding & design
1 reference
stated in
Europe PubMed Central
PubMed ID
9080186
retrieved
21 June 2017
volume
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9080186
retrieved
21 June 2017
page(s)
R121-6
1 reference
stated in
Europe PubMed Central
PubMed ID
9080186
retrieved
21 June 2017
issue
6
1 reference
stated in
Europe PubMed Central
PubMed ID
9080186
retrieved
21 June 2017
cites work
The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)
1 reference
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Additivity of mutational effects in proteins
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Quantitative interpretations of double mutations of enzymes
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Long-range, small magnitude nonadditivity of mutational effects in proteins
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
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inferred from DOI database lookup
Non-additivity in protein-protein interactions
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reference URL
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7 January 2021
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The Effect of Structure upon the Reactions of Organic Compounds. Benzene Derivatives
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7 January 2021
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Estimating the contribution of engineered surface electrostatic interactions to protein stability by using double-mutant cycles
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7 January 2021
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On the choice of reference mutant states in the application of the double-mutant cycle method
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reference URL
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7 January 2021
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Surface electrostatic interactions contribute little of stability of barnase
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reference URL
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7 January 2021
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Aromatic-aromatic interactions and protein stability. Investigation by double-mutant cycles
1 reference
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reference URL
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7 January 2021
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Strength and co-operativity of contributions of surface salt bridges to protein stability
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
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Are buried salt bridges important for protein stability and conformational specificity?
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7 January 2021
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Contributions of a hydrogen bond/salt bridge network to the stability of secondary and tertiary structure in lambda repressor
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7 January 2021
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Importance of two buried salt bridges in the stability and folding pathway of barnase.
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Histidine-aromatic interactions in barnase. Elevation of histidine pKa and contribution to protein stability
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Decomposition of the Free Energy of a System in Terms of Specific Interactions
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The meaning of component analysis: decomposition of the free energy in terms of specific interactions.
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7 January 2021
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Decomposition of interaction free energies in proteins and other complex systems.
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7 January 2021
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Strategy for analysing the co-operativity of intramolecular interactions in peptides and proteins
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7 January 2021
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Co-operative interactions during protein folding.
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Subsite interactions of ribonuclease T1: Asn36 and Asn98 accelerate GpN transesterification through interactions with the leaving nucleoside N.
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Investigation of the functional interplay between the primary site and the subsite of RNase T1: Kinetic analysis of single and multiple mutants for modified substrates
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The net energetic contribution of interhelical electrostatic attractions to coiled-coil stability
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7 January 2021
based on heuristic
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Protein destabilization by electrostatic repulsions in the two-stranded alpha-helical coiled-coil/leucine zipper
1 reference
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7 January 2021
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Thermodynamic characterization of the coupled folding and association of heterodimeric coiled coils (leucine zippers).
1 reference
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7 January 2021
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Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper
1 reference
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7 January 2021
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Response: how much solar radiation do clouds absorb?
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7 January 2021
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Energetics of protein-protein interactions: analysis of the barnase-barstar interface by single mutations and double mutant cycles.
1 reference
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7 January 2021
based on heuristic
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Rapid, electrostatically assisted association of proteins
1 reference
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7 January 2021
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Revealing the architecture of a K+ channel pore through mutant cycles with a peptide inhibitor.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Spatial localization of the K+ channel selectivity filter by mutant cycle-based structure analysis.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prediction of an inter-residue interaction in the chaperonin GroEL from multiple sequence alignment is confirmed by double-mutant cycle analysis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
based on heuristic
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COSMIC analysis of the major alpha-helix of barnase during folding.
1 reference
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7 January 2021
based on heuristic
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The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding
1 reference
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7 January 2021
based on heuristic
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The development of tertiary interactions during the folding of a large protein
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
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The folding of an enzyme. I. Theory of protein engineering analysis of stability and pathway of protein folding
1 reference
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7 January 2021
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The folding of an enzyme. III. Structure of the transition state for unfolding of barnase analysed by a protein engineering procedure
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
based on heuristic
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Molecular basis for nonadditive mutational effects in Escherichia coli dihydrofolate reductase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the role of the KMSKS loop in the catalytic mechanism of the tyrosyl-tRNA synthetase using multimutant cycles
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Thermodynamics and kinetics of single residue replacements in avian ovomucoid third domains: effect on inhibitor interactions with serine proteinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
based on heuristic
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Protein-protein interactions: additivity of the free energies of association of amino acid residues.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
based on heuristic
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Additivity of mutant effects assessed by binomial mutagenesis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
based on heuristic
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Potential use of additivity of mutational effects in simplifying protein engineering
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
based on heuristic
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Contribution of long-range electrostatic interactions to the stabilization of the catalytic transition state of the serine protease subtilisin BPN'
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
based on heuristic
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Long-range surface charge-charge interactions in proteins. Comparison of experimental results with calculations from a theoretical method.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-0278%2896%2900056-9
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7 January 2021
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Identifiers
DOI
10.1016/S1359-0278(96)00056-9
1 reference
stated in
Europe PubMed Central
PubMed ID
9080186
retrieved
21 June 2017
PubMed ID
9080186
1 reference
stated in
Europe PubMed Central
PubMed ID
9080186
retrieved
21 June 2017
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