(Q30434669)

English

Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI). (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

acute lung injury

1 reference

based on heuristic

inferred from title

Alexander Zarbock

1

0 references

Sibylle von Vietinghoff

7

0 references

author name string

Matthew R Distasi

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Emily Smith

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

John M Sanders

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Gerhard Kronke

5

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Brian L Harry

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Konrad Buscher

8

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Jerry L Nadler

9

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Klaus Ley

10

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

language of work or name

0 references

publication date

14 September 2009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Journal of Immunology

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

183

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

4715-4722

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels

1 reference

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14 July 2018

Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators

1 reference

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14 July 2018

A2B adenosine receptor dampens hypoxia-induced vascular leak

1 reference

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14 July 2018

Novel therapies for microvascular permeability in sepsis

1 reference

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14 July 2018

Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation

1 reference

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14 July 2018

The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo

1 reference

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14 July 2018

Treatment of acute lung injury: historical perspective and potential future therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung

1 reference

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14 July 2018

Incidence and outcomes of acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Activation of the 12-lipoxygenase and signal transducer and activator of transcription pathway during neointima formation in a model of the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

The role of CXCR2/CXCR2 ligands in acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

5-Lipoxygenase deficiency prevents respiratory failure during ventilator-induced lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Impaired arachidonic acid-mediated dilation of small mesenteric arteries in Zucker diabetic fatty rats

1 reference

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14 July 2018

In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights

1 reference

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14 July 2018

Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Increased Production of 12/15 Lipoxygenase Eicosanoids Accelerates Monocyte/Endothelial Interactions in Diabetic db/db Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Key role of P38 mitogen-activated protein kinase and the lipoxygenase pathway in angiotensin II actions in H295R adrenocortical cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Lipoxygenase genes and their targeted disruption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Arachidonate 12-lipoxygenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

12/15-lipoxygenase, oxidative modification of LDL and atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Mechanisms regulating endothelial cell barrier function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Evidence that 12-lipoxygenase product 12-hydroxyeicosatetraenoic acid activates p21-activated kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

The acute respiratory distress syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

The arachidonate 12/15 lipoxygenases. A review of tissue expression and biologic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Control of cAMP in lung endothelial cell phenotypes. Implications for control of barrier function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Microvascular permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

12-Lipoxygenase: classification, possible therapeutic benefits from inhibition, and inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

15-Lipoxygenase and its inhibition: a novel therapeutic target for vascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

The role of 15-lipoxygenase in atherogenesis: pro- and antiatherogenic actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Lipoxins and novel aspirin-triggered 15-epi-lipoxins (ATL): a jungle of cell-cell interactions or a therapeutic opportunity?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

The stress-activated c-Jun protein kinase (JNK) is stimulated by lipoxygenase pathway product 12-HETE in RIN m5F cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

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Remodeling of neutrophil phospholipids with 15(S)-hydroxyeicosatetraenoic acid inhibits leukotriene B4-induced neutrophil migration across endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

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Pulmonary dysfunction caused by diffuse lung inflammation. Roles of metabolites of arachidonic acid

1 reference

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Selective incorporation of (15S)-hydroxyeicosatetraenoic acid in phosphatidylinositol of human neutrophils: agonist-induced deacylation and transformation of stored hydroxyeicosanoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Substitution of 15-hydroxyeicosatetraenoic acid in the phosphoinositide signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

14 July 2018

Role of 15-hydroxyeicosatetraenoic acid in phosphorylation of ERK1/2 and caldesmon in pulmonary arterial smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

26 November 2018

15-hydroxyeicosatetraenoic acid depressed endothelial nitric oxide synthase activity in pulmonary artery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

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Leukotrienes in acute lung injury: a potential therapeutic target?

1 reference

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T cells modulate neutrophil-dependent acute renal failure during endotoxemia: critical role for CD28.

1 reference

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12/15-lipoxygenase inhibitors in diabetic nephropathy in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753988

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Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries

1 reference

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12-hydroxyeicosatetrenoate (12-HETE) attenuates AMPA receptor-mediated neurotoxicity: evidence for a G-protein-coupled HETE receptor.

1 reference

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12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice

1 reference

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26 November 2018

The rabbit 15-lipoxygenase preferentially oxygenates LDL cholesterol esters, and this reaction does not require vitamin E.

1 reference

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26 November 2018

Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities.

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19752233

12 December 2020

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Capillary leak. Pathogenesis and treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

12(R)-hydroxy-5,8,10,14-eicosatetraenoic acid is a chemoattractant for human polymorphonuclear leucocytes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection and Significance of Intraoperative and Postoperative Myocardial Ischemic in Peripheral Vascular Surgery

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752233

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based on heuristic

inferred from PubMed ID database lookup

The lipoxygenase metabolite, 12(S)-HETE, induces a protein kinase C-dependent cytoskeletal rearrangement and retraction of microvascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of the oxygenation of phospholipids by the porcine leukocyte and human platelet arachidonate 12-lipoxygenases

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.0802592

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

0 references

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